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Daniel Sinsimer
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Journal Articles

Neutrophil and platelet increases with luspatercept in lower-risk MDS: secondary endpoints from the MEDALIST trial

Clinical Trials & Observations
Guillermo Garcia-Manero, Ghulam J. Mufti, Pierre Fenaux, Rena Buckstein, Valeria Santini, María Díez-Campelo, Carlo Finelli, Osman Ilhan, Mikkael A. Sekeres, Amer M. Zeidan, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Jay T. Backstrom, Uwe Platzbecker, Rami S. Komrokji
Journal: Blood
Blood (2022) 139 (4): 624–629.
https://doi.org/10.1182/blood.2021012589
Published: 2022
Journal Articles

Efficacy and Safety of Luspatercept Treatment in Patients with Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis (MDS/MPN-RS-T): A Retrospective Analysis from the Medalist Study

Rami S. Komrokji, MD, Uwe Platzbecker, Pierre Fenaux, MD PhD, Guillermo Garcia-Manero, MD, Ghulam J. Mufti, Professor, Valeria Santini, Maria Diez-Campelo, PhDMD, Carlo Finelli, Joseph G. Jurcic, MD, Peter L. Greenberg, Mikkael A. Sekeres, Amer M. Zeidan, MBBS, MHS, Amy E. DeZern, MD, Michael R. Savona, MD, Jeevan K. Shetty, Rodrigo Ito, George Zhang, Xianwei Ha, Daniel Sinsimer, Jay T. Backstrom, Amit Verma, MBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–15.
https://doi.org/10.1182/blood-2020-137232
Published: 2020
Journal Articles

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Vip Viprakasit, Ali Taher, Olivier Hermine, John Porter, Antonio Piga, Kevin H. M. Kuo, MDMSc,FRCPC, Thomas Coates, MD, Ersi Voskaridou, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Abderrahmane Laadem, Jeevan K. Shetty, Wen-Ling Kuo, Dimana Miteva, Tatiana Zinger, Daniel Sinsimer, Peter G. Linde, Maria Domenica Cappellini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3545.
https://doi.org/10.1182/blood-2019-122685
Published: 2019
Journal Articles

Hematologic Improvement-Neutrophil and -Platelet in the MEDALIST Trial: Multilineage Data from a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept to Treat Anemia in Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions

Guillermo Garcia-Manero, MD, Ghulam J. Mufti, Pierre Fenaux, MD PhD, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Carlo Finelli, Mario Cazzola, MD, Osman Ilhan, Mikkael A. Sekeres, MD MS, Alan F. List, MD, Abderrahmane Laadem, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Peter G. Linde, Uwe Platzbecker, MD, Rami Komrokji
Journal: Blood
Blood (2019) 134 (Supplement_1): 4243.
https://doi.org/10.1182/blood-2019-123048
Published: 2019
Journal Articles

Effects of Luspatercept on Iron Overload and Impact on Responders to Luspatercept: Results from the BELIEVE Trial

John Porter, Maria Domenica Cappellini, MD, Thomas Coates, MD, Olivier Hermine, Vip Viprakasit, MD DPhil, Ersi Voskaridou, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Abderrahmane Laadem, Jeevan K. Shetty, Wen-Ling Kuo, Dimana Miteva, Tatiana Zinger, Peter G. Linde, Daniel Sinsimer, Ali Taher
Journal: Blood
Blood (2019) 134 (Supplement_1): 2245.
https://doi.org/10.1182/blood-2019-122561
Published: 2019
Journal Articles

Assessment of Longer-Term Efficacy and Safety in the Phase 3, Randomized, Double-Blind, Placebo-Controlled MEDALIST Trial of Luspatercept to Treat Anemia in Patients (Pts) with Revised International Prognostic Scoring System (IPSS-R) Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions

Pierre Fenaux, MD PhD, Ghulam J. Mufti, Rena Buckstein, MD FRCPC, Valeria Santini, MD, María Díez-Campelo, MD PhD, Carlo Finelli, Mario Cazzola, MD, Osman Ilhan, MD, Mikkael A. Sekeres, MD MS, Rami S. Komrokji, MD, Alan F. List, MD, Amer M. Zeidan, MBBS, MHS, Amit Verma, MBBS, Abderrahmane Laadem, Rodrigo Ito, Jennie Zhang, Anita Rampersad, Daniel Sinsimer, Peter G. Linde, Guillermo Garcia-Manero, MD, Uwe Platzbecker, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 841.
https://doi.org/10.1182/blood-2019-123064
Published: 2019