1-11 of 11
David Žihala
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Mara John, Moutaz Helal, Johannes Duell, Greta Mattavelli, Emilia Stanojkovska, Nazia Afrin, Alexander M. Leipold, Maximilian J. Steinhardt, Xiang Zhou, David Žihala, Anjana Anilkumar Sithara, Julia Mersi, Johannes M. Waldschmidt, Christine Riedhammer, Sofie-Katrin Kadel, Marietta Truger, Rudolf A. Werner, Claudia Haferlach, Hermann Einsele, Kai Kretzschmar, Tomáš Jelínek, Andreas Rosenwald, K. Martin Kortüm, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2024) 144 (20): 2121–2135.
https://doi.org/10.1182/blood.2024024590
Published: 2024
Includes: Supplemental data
Journal Articles

Insights into Biological Mechanisms Responsible for Egression of Circulating Tumor Plasma Cells (CTCs) in Multiple Myeloma

Tomas Jelinek, Serafim Nenarokov, Tereza Sevcikova, Eva Radova, Ondrej Venglar, Veronika Kapustova, Lucie Broskevicova, Jan Vrana, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Michal Simicek, Bachisio Ziccheddu, Benjamin Diamond, Francesco Maura, Ola Landgren, David Zihala, Roman Hájek
Journal: Blood
Blood (2024) 144 (Supplement 1): 3270.
https://doi.org/10.1182/blood-2024-206825
Published: 2024
Journal Articles

Composition and Fitness of T and NK Cells in Extramedullary Myeloma Tumor Microenvironment

David Zihala, Anjana Anilkumar Sithara, Veronika Kapustova, Ondrej Venglar, Eva Radova, Lucie Broskevicova, Jan Vrana, Serafim Nenarokov, Daniel Bilek, Ludmila Muronova, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Sandra Charvatova, Kamlesh Bisht, Hongfang Wang, Helgi Van de Velde, Michal Simicek, Tereza Sevcikova, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1887.
https://doi.org/10.1182/blood-2024-206798
Published: 2024
Journal Articles

Predictive Value of Clonal Plasma Cells in Autografts Assessed By Next Generation Flow Cytometry on Pre-Transplant Bone Marrow MRD in Multiple Myeloma Patients

Ondrej Venglar, Eva Radova, David Zihala, Ivana Tvrda, Ludmila Muronova, Veronika Kapustova, Lucie Broskevicova, Jan Vrana, Tereza Popkova, Jana Mihalyova, Hana Plonkova, Tereza Sevcikova, Michal Kascak, Milan Navratil, Zdenek Koristek, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1962.
https://doi.org/10.1182/blood-2024-204692
Published: 2024
Journal Articles

A Multicenter Phase 2 Study Evaluating the Optimized Schedule of Belantamab Mafodotin 1.9 Mg/Kg Q8W Plus Bortezomib and Dexamethasone in Relapsed Refractory Multiple Myeloma

Tereza Popkova, Jakub Radocha, Martin Stork, Jiří Minařík, Jan Straub, Alexandra Jungova, Petr Pavlicek, Tomas Jelinek, Vladimir Maisnar, Ludek Pour, Tomas Pika, František Sedlák, Jan Soukup, Hana Plonkova, Ludmila Muronova, Viera Sandecka, Petra Krhovska, David Zihala, Roman Hajek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1999.
https://doi.org/10.1182/blood-2024-211224
Published: 2024
Journal Articles

Depletion of Mature B Cells and of Normal Plasma Cells (PC) behind the Higher Incidence of Infections after Anti-BCMA VS Anti-GPRC5D Bispecific Antibodies (bsAb) in Relapsed Refractory Multiple Myeloma (RRMM)

Tomas Jelinek, David Zihala, Aintzane Zabaleta, Ioannis V Kostopoulos, Ondrej Soucek, Ondrej Venglar, Cristina Moreno, Despina Fotiou, Eva Radova, Luis-Esteban Tamariz-Amador, Foteini Theodorakakou, Ludmila Muronova, Andrea Manubens, Ourania Tsitsilonis, Tereza Popkova, Lucie Broskevicova, Jana Mihalyova, Tereza Sevcikova, Jesús F. San-Miguel, Meletios Dimopoulos, Paula Rodríguez-Otero, Jakub Radocha, Efstathios Kastritis, Bruno Paiva, Roman Hajek
Journal: Blood
Blood (2024) 144 (Supplement 1): 1934.
https://doi.org/10.1182/blood-2024-205481
Published: 2024
Journal Articles

Circulating Plasma Cells Are the Most Powerful Prognostic Marker in Transplant Ineligible Multiple Myeloma with 2% As a New Cut-Off for Primary Plasma Cell Leukemia

Tomas Jelinek, Renata Bezděková, David Zihala, Tereza Sevcikova, Lenka Capkova, Petra Polackova, Martin Stork, Zdenka Knechtova, Ondrej Venglar, Artur Jurczyszyn, Jorge J. Castillo, Miroslav Penka, Jakub Radocha, Sabina Sevcikova, Ludek Pour, Lucie Rihova, Roman Hajek
Journal: Blood
Blood (2021) 138 (Supplement 1): 546.
https://doi.org/10.1182/blood-2021-151592
Published: 2021
Journal Articles

Pathogenesis of Extramedullary Multiple Myeloma: From Resistance to Identification of Novel Therapeutic Targets

Tomas Jelinek, David Zihala, Tereza Sevcikova, Veronika Kapustova, Hana Sahinbegovic, Anjana Anilkumar Sithara, Tereza Popkova, Hana Plonkova, Lucie Broskevicova, Jan Vrana, Vladimir Zidlik, Martin Havel, Zdenek Koristek, Juli R. Bago, Michal Simicek, Roman Hajek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2680.
https://doi.org/10.1182/blood-2021-150876
Published: 2021
Journal Articles

Effect of Daratumumab-Containing Induction on CD34+ Hematopoietic Stem Cells before Autologous Stem Cell Transplantation in Multiple Myeloma

Ondrej Venglar, Tereza Sevcikova, Anjana Anilkumar Sithara, Veronika Kapustova, Jan Vrana, David Zihala, Ludmila Muronova, Lucie Huvarova, Lucie Broskevicova, Michal Simicek, Zdenek Koristek, Roman Hajek, Tomas Jelinek
Journal: Blood
Blood (2021) 138 (Supplement 1): 2764.
https://doi.org/10.1182/blood-2021-150360
Published: 2021
Journal Articles

Identification of Molecular Mechanisms Responsible for the Development of Extramedullary Disease in Myeloma and Potential Novel Therapeutic Targets Using Transcriptomic and Exome Profiling

David Zihala, Tereza Sevcikova, Michal Simicek, Tereza Popkova, Hana Plonkova, Lucie Broskevicova, Jan Vrana, Juli R. Bago, Roman Hajek, Giovanni Stracquadanio, Tomas Jelinek
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-142300
Published: 2020
Journal Articles

Identification of Novel Regulatory Pathway for Immunoglobulin Production Provides Rational Treatment for Bortezomib-Resistant Multiple Myeloma Patients

Alexander Vdovin, Michal Durech, PhD, Tomas Jelinek, Tereza Sevcikova, PhD, Juli R. Bago, Matous Hrdinka, PhD, David Zihala, Renata Snaurova, Hana Sahinbegovic, Tereza Popkova, Ryszard Smolarczyk, PhD, Tomasz Cichon, PhD, Sebastian Giebel, MDPhD, Roman Hajek, MD PhD, Michal Simicek, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–42.
https://doi.org/10.1182/blood-2020-140673
Published: 2020