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Journal Articles

A Novel Direct Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease - In Vivo Efficacy of Ilx-002 in Humanized Mice

Osheiza Abdulmalik, Kandace Gollomp, Veronica Bochenek, Conroy O Field, Mariana Macias, Benita Balogun, Salma Roland, Martin K Safo, Yan Zhang, Akua Donkor, Abdelsattar Omar, Moustafa El-Araby, David R. Light, Clark Brown, Andrew N Fleischman
Journal: Blood
Blood (2024) 144 (Supplement 1): 173.
https://doi.org/10.1182/blood-2024-202714
Published: 2024
Journal Articles

Anti-Phospholipid Syndrome (APS) Antibody (Ab)-Induced Thrombosis Can be Blocked By Platelet Factor 4 (PF4)-Directed Abs: A Novel Therapeutic Approach for APS?

Amrita Sarkar, Santosh K Yadav, Conroy O Field, Kandace Gollomp, Keith R. McCrae, Thomas L. Ortel, Yves Gruel, Jérôme Rollin, Gowthami M Arepally, Lubica Rauova, Douglas B. Cines, Mortimer Poncz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2611.
https://doi.org/10.1182/blood-2024-200849
Published: 2024
Journal Articles

The PF4-Centric Immunothrombotic Disorders, HIT, Vitt and APS, Lead to Complement Activation Responsive to Complement-Blocking Therapeutics

Amrita Sarkar, Conroy O Field, Keith R. McCrae, Thomas L. Ortel, Gow Arepally, Roxanne Cofiell, Sung-Kwon Kim, Lubica Rauova, Mortimer Poncz
Journal: Blood
Blood (2024) 144 (Supplement 1): 2606.
https://doi.org/10.1182/blood-2024-198182
Published: 2024
Journal Articles

Antiphospholipid Syndrome (APS) Is a Platelet Factor 4 (PF4)-Centric Immunothrombotic Disorder

Conroy O Field, Amrita Sarkar, Khalil Bdeir, Keith R. McCrae, Thomas L. Ortel, M. Anna Kowalska, Lubica Rauova, Douglas B. Cines, Kandace Gollomp, Mortimer Poncz
Journal: Blood
Blood (2024) 144 (Supplement 1): 185.
https://doi.org/10.1182/blood-2024-201682
Published: 2024