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Journal Articles

Age-Related Changes in Hematopoietic Stem Cell Proteostasis Promote the Emergence of Clonal Hematopoiesis and Leukemia in Older Adults

Fanny Jiahua J. Zhou, Helen C. Wang, Michelle K. Le, Wei Yang, Mary Jean Sunshine, Jeffrey A. Magee, Robert Signer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4047.
https://doi.org/10.1182/blood-2024-202652
Published: 2024
Journal Articles

Outcomes of Immunosuppressive Therapy in Children Less Than Three Years of Age with Idiopathic Severe Aplastic Anemia: A North American Collaboration

Talya Wittmann Dayagi, Laura Willis, Catherine Corriveau-Bourque, Michaela Cada, Zora R. Rogers, Taizo A. Nakano, Timothy S. Olson, Winfred C. Wang, Alfred Gillio, Thomas D. Coates, Anjulika Chawla, Paul Castillo, Peter Kurre, Christopher Gamper, Staci D. Arnold, Sarita Joshi, Amy E. Geddis, Jessica Boklan, Jennifer A. Rothman, James N. Huang, Gary M. Kupfer, Bertil Glader, Kelly J. Walkovich, Alexis Thompson, Rabi Hanna, David A. Williams, Akiko Shimamura, Yigal Dror
Journal: Blood
Blood (2024) 144 (Supplement 1): 2691.
https://doi.org/10.1182/blood-2024-198302
Published: 2024
Journal Articles

The Natural History of Glomerular Hyperfiltration in Sickle Cell Disease

Rima Zahr, Shuyan Chen, Parul Rai, Jane S Hankins, Winfred C. Wang, Jeffrey D Lebensburger, Guolian Kang, Kenneth I. Ataga
Journal: Blood
Blood (2024) 144 (Supplement 1): 3886.
https://doi.org/10.1182/blood-2024-199586
Published: 2024
Journal Articles

Novel Drug to Target HK2 Overcomes Therapeutic Resistance in Preclinical B-Cell Lymphoma Models

Juan Gu, Cory Mavis, Jessica C Wang, Kevin Bowman, Taylor K Mandeville, Ahmet E Tatar, Zepnep Benekli, Matthew J Cortese, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 5793.
https://doi.org/10.1182/blood-2023-185189
Published: 2023
Journal Articles

Compatibility of Venetoclax and OPN51107 in Treatment of Mantle Cell Lymphoma

Kevin Bowman, Cory Mavis, Juan Gu, Taylor K Mandeville, Jessica C Wang, Matthew J Cortese, Francisco J. Hernandez-Ilizaliturri
Journal: Blood
Blood (2023) 142 (Supplement 1): 6102.
https://doi.org/10.1182/blood-2023-189739
Published: 2023
Journal Articles

Divergent Roles of MLL3 and MLL4 in Hematopoietic Stem Cell Fate Decision

Helen C. Wang, Ran Chen, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jeffrey Magee
Journal: Blood
Blood (2023) 142 (Supplement 1): 400.
https://doi.org/10.1182/blood-2023-178765
Published: 2023
Journal Articles

KMT2C/ MLL3 Attenuates Committed Myeloid Progenitor Self-Renewal Capacity and Balances Granulocyte and Monocyte/Dendritic Cell Output

Helen C. Wang, Ran Chen, Wei Yang, Riddhi M Patel, Emily B Casey, Jeffrey A. Magee
Journal: Blood
Blood (2022) 140 (Supplement 1): 4485–4486.
https://doi.org/10.1182/blood-2022-165717
Published: 2022
Journal Articles

Eltrombopag in Pediatric Patients with Previously Untreated or Refractory/Relapsed Severe Aplastic Anemia: The Phase II Escalate Trial

Akiko Shimamura, Alexey Maschan, Carolyn Bennett, Jason E Farrar, Sujith Samarasinghe, Brigitte Strahm, Winfred C. Wang, Adrianna Vlachos, Charlotte M. Niemeyer, Timothy S. Olson, Denise D'Alessio, Elise Burmeister Getz, Tomasz Lawniczek, Yunnan Xu, David A. Williams
Journal: Blood
Blood (2022) 140 (Supplement 1): 705–707.
https://doi.org/10.1182/blood-2022-158214
Published: 2022
Journal Articles

Hydroxyurea Dosing in Very Young Children (HUGKISS): Challenges of Study Design

Meghna Dua, Winfred C. Wang, Timothy McCavit, Suvankar Majumdar, R. Clark Brown, Zora R. Rogers, Jeffrey Gossett, Guolian Kang, Jeremie H. Estepp
Journal: Blood
Blood (2022) 140 (Supplement 1): 11108–11109.
https://doi.org/10.1182/blood-2022-165760
Published: 2022
Journal Articles

Hydroxyurea Dosing in Very Young Children with Sickle Cell Anemia: A Multicenter, Randomized, Controlled Trial (HUGKISS)

Meghna Dua, Winfred C. Wang, R. Clark Brown, Melissa A. McNaull, Zora R. Rogers, Martha Barton, Jane Hankins, Jeffrey Gossett, Julie Richardson, Jerlym S. Porter, Guolian Kang, Jeremie H. Estepp
Journal: Blood
Blood (2022) 140 (Supplement 1): 445–446.
https://doi.org/10.1182/blood-2022-160485
Published: 2022
Journal Articles

Optimizing the Frequency of Transcranial Doppler (TCD) Exams in Children with Sickle Cell Anemia

Ayobami Olanrewaju, Zachary Abramson, Jane S Hankins, Clifford Takemoto, M. Beth McCarville, Andrew M Heitzer, Guolian Kang, Victoria Okhomina, Winfred C. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 2142–2144.
https://doi.org/10.1182/blood-2022-159500
Published: 2022
Journal Articles

Targeting Oncoproteins with a Positive Selection Assay for Protein Degraders

Sagar Koduri, MD PhD, Adam C. Wang, B.S., Mette Ishoey, PhD, Joshiawa Paulk, Xiaoxi Liu, PhD, Isaac Harris, PhD, Jennifer Endress, B.S., Benjamin L. Lampson, MD PhD, Christopher J. Ott, PhD, James Bradner, MD, Jeffrey A. Medin, PhD, Sara J Buhrlage, PhD, William Kaelin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-141558
Published: 2020
Journal Articles

Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study

Clinical Trials & Observations
Rachael F. Grace, Paola Bianchi, Eduard J. van Beers, Stefan W. Eber, Bertil Glader, Hassan M. Yaish, Jenny M. Despotovic, Jennifer A. Rothman, Mukta Sharma, Melissa M. McNaull, Elisa Fermo, Kimberly Lezon-Geyda, D. Holmes Morton, Ellis J. Neufeld, Satheesh Chonat, Nina Kollmar, Christine M. Knoll, Kevin Kuo, Janet L. Kwiatkowski, Dagmar Pospíšilová, Yves D. Pastore, Alexis A. Thompson, Peter E. Newburger, Yaddanapudi Ravindranath, Winfred C. Wang, Marcin W. Wlodarski, Heng Wang, Susanne Holzhauer, Vicky R. Breakey, Joachim Kunz, Sujit Sheth, Melissa J. Rose, Heather A. Bradeen, Nolan Neu, Dongjing Guo, Hasan Al-Sayegh, Wendy B. London, Patrick G. Gallagher, Alberto Zanella, Wilma Barcellini
Journal: Blood
Blood (2018) 131 (20): 2183–2192.
https://doi.org/10.1182/blood-2017-10-810796
Published: 2018
Includes: Supplemental data
Journal Articles

Hydroxyurea at Maximal Tolerated Dose (MTD) Prior to Completion of the β-Globin Switch Has Additive but Not Sustained Benefits in Fetal Hemoglobin Production

Christina Abrams, MD, Joseph Moen, MS, Guolian Kang, PhD, Winfred C. Wang, MD, Jane Hankins, MD MS, Jeremie H. Estepp, MD
Journal: Blood
Blood (2016) 128 (22): 125.
https://doi.org/10.1182/blood.V128.22.125.125
Published: 2016
Journal Articles

Iron Overload Is Highly Prevalent in All Disease Severity States in Pyruvate Kinase Deficiency (PKD)

Eduard J van Beers, MD PhD, Wilma Barcellini, Stefan W. Eber, MD, Janet L Kwiatkowski, MD, Jennifer A Rothman, MD, Ellis J Neufeld, MD PhD, Mukta Sharma, MD MPH, D Holmes Morton, MD, Bertil Glader, MD PhD, Nina Kollmar, MD, Hassan M. Yaish, Jenny M. Despotovic, DO, MS, Christine M. Knoll, MD, Yves D. Pastore, MD, Kevin Kuo, BSc, MD, Peter E. Newburger, MD, Marcin W Wlodarski, MD, Alexis A. Thompson, MD MPH, Yaddanapudi Ravindranath, Winfred C. Wang, MD, Heng Wang, MD, Joachim B. Kunz, MD, Vicky R. Breakey, BSc, MD MD FRCPC, Melissa J. Rose, DO, Melissa Rhodes, MD, Heather A Bradeen, MD, Sujit Sheth, MD, Dongjing Guo, MS, Wendy B. London, PhD, Rachael F. Grace, MD
Journal: Blood
Blood (2016) 128 (22): 2430.
https://doi.org/10.1182/blood.V128.22.2430.2430
Published: 2016
Journal Articles

Genetic Variations in Calicheamicin Pathway Genes Are Predictors of Gemtuzumab Ozogamicin Response in AML Patients: Results from COG-AAML0531 Study

Jatinder K Lamba, PhD, Lata Chauhan, PhD, Richard Aplenc, MD PhD, Maggie Skrypek, MD, Jessica Pollard, MD, Todd A. Alonzo, PhD, Y-C Wang, Irwin D. Bernstein, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1260.
https://doi.org/10.1182/blood.V126.23.1260.1260
Published: 2015
Journal Articles

Prognostic Factors for Hospitalization of Children with Sickle Cell Anemia Treated with Hydroxyurea at Maximum Tolerated Dose

Jeremie H. Estepp, MD, Qinlei T. Huang, MS, Winfred C. Wang, MD, Guolian Kang, PhD
Journal: Blood
Blood (2015) 126 (23): 2177.
https://doi.org/10.1182/blood.V126.23.2177.2177
Published: 2015
Journal Articles

High Failure Rate with Brigance Developmental Screening in 3 Year-Old Children with Sickle Cell Disease

Winfred C. Wang, MD, Molly Beth Freeman, MS, Yvonne M. Carroll, JD, RN, Latacha Hamilton, EdS, Matthew P. Smeltzer, MStat, PhD, Guolian Kang, PhD, Jane S. Hankins, MD MS, Banu Aygun, MD
Journal: Blood
Blood (2014) 124 (21): 4926.
https://doi.org/10.1182/blood.V124.21.4926.4926
Published: 2014
Journal Articles

Brain MRI/MRA Findings after Hydroxyurea Treatment in Children with Sickle Cell Anemia

Kerri Nottage, MD MPH, Russell E. Ware, MD PhD, Matthew P. Smeltzer, MStat, PhD, Jola Dowdy, MS, Winfred C. Wang, MD, Jane S. Hankins, MD MS, Kathleen J. Helton, MD, Banu Aygun, MD
Journal: Blood
Blood (2014) 124 (21): 89.
https://doi.org/10.1182/blood.V124.21.89.89
Published: 2014
Journal Articles

Transplant Outcome of Pediatric and Young Adult Patients with Aplastic Anemia: St Jude Children’s Research Hospital Experience

Hesham Eissa, MD, Brandon M. Triplett, MD, Mari H Dallas, MD, Ashok Srinivasan, MD, Christine Hartford, MD, Ulrike M. Reiss, MD, Winfred C. Wang, MD, Wing Leung, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1210.
https://doi.org/10.1182/blood.V124.21.1210.1210
Published: 2014