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Volume 133, Issue 26

June 27 2019

In this Issue

BLOOD COMMENTARIES
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
LYMPHOID NEOPLASIA
TRANSPLANTATION
LETTERS TO BLOOD
BLOOD WORK

Table of Contents

BLOOD COMMENTARIES

GENE THERAPY

Gene editing in hemophilia: a “CRISPR” choice?

Steven W. Pipe,Sundar R. Selvaraj

View Articletitled, Gene editing in hemophilia: a “CRISPR” choice?

Lymphoid Neoplasia

Deciphering hydroa vacciniforme

Leticia Quintanilla-Martinez,Falko Fend

View Articletitled, Deciphering hydroa vacciniforme

Lymphoid Neoplasia

A one-two punch with VO KOs CLL

Steven Coutre

View Articletitled, A one-two punch with VO KOs CLL

TRANSPLANTATION

Nuke less for less cancer

Mohamad Mohty

View Articletitled, Nuke less for less cancer

CLINICAL TRIALS AND OBSERVATIONS

Proteomic evidence of specific IGKV1-8 association with cystic lung light chain deposition disease
Clinical Trials & Observations Brief Report

Mylène Camus,Sandrine Hirschi,Grégoire Prevot,Marie-Pierre Chenard,Hervé Mal,Marc Stern,Martine Reynaud-Gaubert,Julia Gilhodes,Odile Burlet-Schiltz,Pierre Brousset,Magali Colombat

View Articletitled, Proteomic evidence of specific IGKV1-8 association with cystic lung light chain deposition disease

Supplemental data

GENE THERAPY

CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX–knockout mice

Lili Wang,Yang Yang,Camilo Ayala Breton,John White,Jia Zhang,Yan Che,Alexei Saveliev,Deirdre McMenamin,Zhenning He,Caitlin Latshaw,Mingyao Li,James M. Wilson

View Articletitled, CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX–knockout mice

Supplemental data

LYMPHOID NEOPLASIA

Hydroa vacciniforme–like lymphoproliferative disorder: an EBV disease with a low risk of systemic illness in whites
Clinical Trials & Observations

Jeffrey I. Cohen,Irini Manoli,Kennichi Dowdell,Tammy A. Krogmann,Deborah Tamura,Pierce Radecki,Wei Bu,Siu-Ping Turk,Kelly Liepshutz,Ronald L. Hornung,Hiva Fassihi,Robert P. Sarkany,Lori L. Bonnycastle,Peter S. Chines,Amy J. Swift,Timothy G. Myers,Melissa A. Levoska,John J. DiGiovanna,Francis S. Collins,Kenneth H. Kraemer,Stefania Pittaluga,Elaine S. Jaffe

There is a Blood Commentary on this article in this issue.

View Articletitled, Hydroa vacciniforme–like lymphoproliferative disorder: an EBV disease with a low risk of systemic illness in whites

Supplemental data

Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia
Clinical Trials & Observations

Ian W. Flinn,John G. Gribben,Martin J. S. Dyer,William Wierda,Michael B. Maris,Richard R. Furman,Peter Hillmen,Kerry A. Rogers,Swaminathan Padmanabhan Iyer,Anne Quillet-Mary,Loic Ysebaert,Harriet S. Walter,Maria Verdugo,Christian Klein,Huang Huang,Yanwen Jiang,Gerard Lozanski,Daniela Soriano Pignataro,Kathryn Humphrey,Mehrdad Mobasher,Thomas J. Kipps

There is a Blood Commentary on this article in this issue.

View Articletitled, Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia

Supplemental data

Recurrent MSC^E116K mutations in ALK-negative anaplastic large cell lymphoma

Rebecca A. Luchtel,Michael T. Zimmermann,Guangzhen Hu,Surendra Dasari,Manli Jiang,Naoki Oishi,Hailey K. Jacobs,Yu Zeng,Tanya Hundal,Karen L. Rech,Rhett P. Ketterling,Jeong-Heon Lee,Bruce W. Eckloff,Huihuang Yan,Krutika S. Gaonkar,Shulan Tian,Zhenqing Ye,Marshall E. Kadin,Jagmohan Sidhu,Liuyan Jiang,Jesse Voss,Brian K. Link,Sergei I. Syrbu,Fabio Facchetti,N. Nora Bennani,Susan L. Slager,Tamas Ordog,Jean-Pierre Kocher,James R. Cerhan,Stephen M. Ansell,Andrew L. Feldman

View Articletitled, Recurrent <em>MSC</em><sup>E116K</sup> mutations in ALK-negative anaplastic large cell lymphoma

Supplemental data

TRANSPLANTATION

Total body irradiation dose and risk of subsequent neoplasms following allogeneic hematopoietic cell transplantation
Clinical Trials & Observations

K. Scott Baker,Wendy M. Leisenring,Pamela J. Goodman,Ralph P. Ermoian,Mary E. Flowers,G. Schoch,Rainer Storb,Brenda M. Sandmaier,H. Joachim Deeg

View Articletitled, Total body irradiation dose and risk of subsequent neoplasms following allogeneic hematopoietic cell transplantation

Supplemental data

LETTERS TO BLOOD

Safety of CAR T-cell therapy in patients with B-cell lymphoma and chronic hepatitis B or C virus infection
Clinical Trials & Observations

Paolo Strati,Loretta J. Nastoupil,Luis E. Fayad,Felipe Samaniego,Sherry Adkins,Sattva S. Neelapu

View Articletitled, Safety of CAR T-cell therapy in patients with B-cell lymphoma and chronic hepatitis B or C virus infection

Spectrum of ASXL1 mutations in primary myelofibrosis: prognostic impact of the ASXL1 p.G646Wfs*12 mutation

Giada Rotunno,Carmela Mannarelli,Giada Brogi,Annalisa Pacilli,Francesca Gesullo,Francesco Mannelli,Sara Fiaccabrino,Benedetta Sordi,Chiara Paoli,Ilaria Marone,Elisa Rumi,Rossella Manfredini,Giovanni Barosi,Mario Cazzola,Alessandro M. Vannucchi,Paola Guglielmelli

View Articletitled, Spectrum of <em>ASXL1</em> mutations in primary myelofibrosis: prognostic impact of the <em>ASXL1</em> p.G646Wfs*12 mutation

Supplemental data

BLOOD WORK

Striking emperipolesis in megakaryocytes of gray platelet syndrome

Eric McGinnis,Kate M. Chipperfield

View Articletitled, Striking emperipolesis in megakaryocytes of gray platelet syndrome

Cover Image

Cover Image

Eosinophilic extracellular amorphous Congo red–negative deposits admixed with some plasma cells without atypia are the histological hallmark of pulmonary light chain deposition disease (LCDD), an entity clinically and molecularly distinct from systemic LCDD. See the article by Camus et al on page 2741.
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