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Journal Articles

Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease

Sheila K. Pierson, Sushila Shenoy, Ana B. Oromendia, Alexander M. Gorzewski, Ruth-Anne Langan Pai, Christopher Shield Nabel, Jason R. Ruth, Sophia A. T. Parente, Daniel J. Arenas, Mary Guilfoyle, Manjula Reddy, Michael Weinblatt, Nancy Shadick, Mark Bower, Alessia Dalla Pria, Yasufumi Masaki, Laura Katz, Jason Mezey, Philip Beineke, David Lee, Craig Tendler, Taku Kambayashi, Alexander Fosså, Frits van Rhee, David C. Fajgenbaum
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3445–3456.
https://doi.org/10.1182/bloodadvances.2020004016
Published: 2021
Includes: Supplemental data
Journal Articles

Activated IL-6 signaling contributes to the pathogenesis of, and is a novel therapeutic target for, CALR -mutated MPNs

Manjola Balliu, Laura Calabresi, Niccolò Bartalucci, Simone Romagnoli, Laura Maggi, Rossella Manfredini, Matteo Lulli, Paola Guglielmelli, Alessandro Maria Vannucchi
Journal: Blood Advances
Blood Adv (2021) 5 (8): 2184–2195.
https://doi.org/10.1182/bloodadvances.2020003291
Published: 2021
Includes: Supplemental data
Journal Articles

Selective drug combination vulnerabilities in STAT3- and TP53-mutant malignant NK cells

Elina Parri, Heikki Kuusanmäki, Daria Bulanova, Satu Mustjoki, Krister Wennerberg
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1862–1875.
https://doi.org/10.1182/bloodadvances.2020003300
Published: 2021
Includes: Supplemental data
Journal Articles

Proteomic profiling of HTLV-1 carriers and ATL patients reveals sTNFR2 as a novel diagnostic biomarker for acute ATL

Carmina Louise Hugo Guerrero, Yoshiko Yamashita, Megumi Miyara, Naoki Imaizumi, Megumi Kato, Shugo Sakihama, Masaki Hayashi, Takashi Miyagi, Kaori Karimata, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Sawako Nakachi, Satoko Morishima, Kennosuke Karube, Yuetsu Tanaka, Hiroaki Masuzaki, Takuya Fukushima
Journal: Blood Advances
Blood Adv (2020) 4 (6): 1062–1071.
https://doi.org/10.1182/bloodadvances.2019001429
Published: 2020
Includes: Supplemental data
Journal Articles

Expression of the prosurvival kinase HCK requires PAX5 and mutated MYD88 signaling in MYD88-driven B-cell lymphomas

Xia Liu, Jiaji G. Chen, Manit Munshi, Zachary R. Hunter, Lian Xu, Amanda Kofides, Nickolas Tsakmaklis, Maria G. Demos, Maria Luisa Guerrera, Gloria G. Chan, Cristina Jimenez, Christopher J. Patterson, Kirsten Meid, Andrew Keezer, Jorge J. Castillo, Steven P. Treon, Guang Yang
Journal: Blood Advances
Blood Adv (2020) 4 (1): 141–153.
https://doi.org/10.1182/bloodadvances.2019000947
Published: 2020
Journal Articles

STAT3β is a tumor suppressor in acute myeloid leukemia

Petra Aigner, Tatsuaki Mizutani, Jaqueline Horvath, Thomas Eder, Stefan Heber, Karin Lind, Valentin Just, Herwig P. Moll, Assa Yeroslaviz, Michael J. M. Fischer, Lukas Kenner, Balázs Győrffy, Heinz Sill, Florian Grebien, Richard Moriggl, Emilio Casanova, Dagmar Stoiber
Journal: Blood Advances
Blood Adv (2019) 3 (13): 1989–2002.
https://doi.org/10.1182/bloodadvances.2018026385
Published: 2019
Includes: Supplemental data
Journal Articles

Morphine promotes neovascularizing retinopathy in sickle transgeneic mice

Kalpna Gupta, Chunsheng Chen, Gerard A. Lutty, Robert P. Hebbel
Journal: Blood Advances
Blood Adv (2019) 3 (7): 1073–1083.
https://doi.org/10.1182/bloodadvances.2018026898
Published: 2019
Includes: Supplemental data
Journal Articles

Subclonal STAT3 mutations solidify clonal dominance

Cassandra M. Kerr, Michael J. Clemente, Peter W. Chomczynski, Bartlomiej Przychodzen, Yasunobu Nagata, Vera Adema, Valeria Visconte, Alan E. Lichtin, Satu Mustjoki, Tomas Radivoyevitch, Mikkael A. Sekeres, Jaroslaw P. Maciejewski
Journal: Blood Advances
Blood Adv (2019) 3 (6): 917–921.
https://doi.org/10.1182/bloodadvances.2018027862
Published: 2019
Includes: Supplemental data
Journal Articles

PD-L1 and tumor-associated macrophages in de novo DLBCL

Clinical Trials & Observations
Ronald McCord, Christopher R. Bolen, Hartmut Koeppen, Edward E. Kadel, III, Mikkel Z. Oestergaard, Tina Nielsen, Laurie H. Sehn, Jeffrey M. Venstrom
Journal: Blood Advances
Blood Adv (2019) 3 (4): 531–540.
https://doi.org/10.1182/bloodadvances.2018020602
Published: 2019
Includes: Supplemental data
Journal Articles

Frequent STAT3 mutations in CD8 + T cells from patients with pure red cell aplasia

Clinical Trials & Observations
Toru Kawakami, Nodoka Sekiguchi, Jun Kobayashi, Tatsuya Imi, Kazuyuki Matsuda, Taku Yamane, Sayaka Nishina, Yasushi Senoo, Hitoshi Sakai, Toshiro Ito, Tomonobu Koizumi, Makoto Hirokawa, Shinji Nakao, Hideyuki Nakazawa, Fumihiro Ishida
Journal: Blood Advances
Blood Adv (2018) 2 (20): 2704–2712.
https://doi.org/10.1182/bloodadvances.2018022723
Published: 2018
Includes: Supplemental data
Journal Articles

Systematic STAT3 sequencing in patients with unexplained cytopenias identifies unsuspected large granular lymphocytic leukemia

Elizabeth A. Morgan, Mark N. Lee, Daniel J. DeAngelo, David P. Steensma, Richard M. Stone, Frank C. Kuo, Jon C. Aster, Christopher J. Gibson, R. Coleman Lindsley
Journal: Blood Advances
Blood Adv (2017) 1 (21): 1786–1789.
https://doi.org/10.1182/bloodadvances.2017011197
Published: 2017
Includes: Supplemental data