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Journal Articles

Response to upfront azacitidine in juvenile myelomonocytic leukemia in the AZA-JMML-001 trial

Free
Clinical Trials & Observations
Charlotte M. Niemeyer, Christian Flotho, Daniel B. Lipka, Jan Starý, Claudia Rössig, André Baruchel, Thomas Klingebiel, Concetta Micalizzi, Gérard Michel, Karsten Nysom, Susana Rives, Markus Schmugge Liner, Marco Zecca, Maximilian Schönung, Irith Baumann, Peter Nöllke, Bouchra Benettaib, Noha Biserna, Jennifer Poon, Mathew Simcock, Meera Patturajan, Daniel Menezes, Allison Gaudy, Marry M. van den Heuvel-Eibrink, Franco Locatelli
Journal: Blood Advances
Blood Adv (2021) 5 (14): 2901–2908.
https://doi.org/10.1182/bloodadvances.2020004144
Published: 2021
Includes: Supplemental data
Journal Articles

Population pharmacokinetics of the von Willebrand factor–factor VIII interaction in patients with von Willebrand disease

Free
Laura H. Bukkems, Jessica M. Heijdra, Nico C. B. de Jager, Hendrika C. A. M. Hazendonk, Karin Fijnvandraat, Karina Meijer, Jeroen C. J. Eikenboom, Britta A. P. Laros-van Gorkom, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1513–1522.
https://doi.org/10.1182/bloodadvances.2020003891
Published: 2021
Includes: Supplemental data
Journal Articles

Thioridazine requires calcium influx to induce MLL-AF6 –rearranged AML cell death

Free
Claudia Tregnago, Ambra Da Ros, Elena Porcù, Maddalena Benetton, Manuela Simonato, Luca Simula, Giulia Borella, Katia Polato, Sonia Minuzzo, Giulia Borile, Paola Cogo, Silvia Campello, Alessandro Massi, Romeo Romagnoli, Barbara Buldini, Franco Locatelli, Martina Pigazzi
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4417–4429.
https://doi.org/10.1182/bloodadvances.2020002001
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734

Free
Filippo Spriano, Eugenio Gaudio, Luciano Cascione, Chiara Tarantelli, Federica Melle, Giovanna Motta, Valdemar Priebe, Andrea Rinaldi, Gaetanina Golino, Afua Adjeiwaa Mensah, Luca Aresu, Emanuele Zucca, Stefano Pileri, Michael Witcher, Bill Brown, Claes Wahlestedt, Francis Giles, Anastasios Stathis, Francesco Bertoni
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4124–4135.
https://doi.org/10.1182/bloodadvances.2020001879
Published: 2020
Includes: Supplemental data
Journal Articles

Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome

Free
Clinical Trials & Observations
Je-Hwan Lee, Stefan Faderl, John M. Pagel, Chul Won Jung, Sung-Soo Yoon, Animesh D. Pardanani, Pamela S. Becker, Howard Lee, Jeongeun Choi, Kyoungjune Lee, Minkyoung Kim, Jorge E. Cortes
Journal: Blood Advances
Blood Adv (2020) 4 (9): 2032–2043.
https://doi.org/10.1182/bloodadvances.2019000757
Published: 2020
Includes: Supplemental data
Journal Articles

FVIII half-life extension by coadministration of a D′D3 albumin fusion protein in mice, rabbits, rats, and monkeys

Free
Sabine Pestel, Hans-Wilhelm Beltz, Philipp Claar, Holger Lind, Marcel Mischnik, Elmar Raquet, Arna Andrews, Jason Simmonds, Vesna Tomasetig, Steven K. Dower, Anna Tjärnlund-Wolf, Stefan Schulte, Peter M. Schmidt, Thomas Weimer
Journal: Blood Advances
Blood Adv (2020) 4 (9): 1870–1880.
https://doi.org/10.1182/bloodadvances.2019000999
Published: 2020
Includes: Supplemental data
Journal Articles

CyBorD-DARA is potent initial induction for MM and enhances ADCP: initial results of the 16-BCNI-001/CTRIAL-IE 16-02 study

Free
Clinical Trials & Observations
M. O’Dwyer, R. Henderson, S. D. Naicker, M. R. Cahill, P. Murphy, V. Mykytiv, J. Quinn, C. McEllistrim, J. Krawczyk, J. Walsh, E. Lenihan, T. Kenny, A. Hernando, G. Hirakata, I. Parker, E. Kinsella, G. Gannon, A. Natoni, K. Lynch, A. E. Ryan
Journal: Blood Advances
Blood Adv (2019) 3 (12): 1815–1825.
https://doi.org/10.1182/bloodadvances.2019000010
Published: 2019
Includes: Supplemental data
Journal Articles

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Free
Manu T. Kalathottukaren, A. Louise Creagh, Srinivas Abbina, Genmin Lu, Mark J. Karbarz, Anjali Pandey, Pamela B. Conley, Jayachandran N. Kizhakkedathu, Charles Haynes
Journal: Blood Advances
Blood Adv (2018) 2 (16): 2104–2114.
https://doi.org/10.1182/bloodadvances.2016003616
Published: 2018
Includes: Supplemental data
Journal Articles

Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa

Free
Deborah Siegal, Genmin Lu, Janet M. Leeds, Mark Karbarz, Janice Castillo, Vandana Mathur, Athiwat Hutchaleelaha, Uma Sinha, Michael Kitt, Matt McClure, Stanley J. Hollenbach, John T. Curnutte, Pamela B. Conley, Mark Crowther
Journal: Blood Advances
Blood Adv (2017) 1 (21): 1827–1838.
https://doi.org/10.1182/bloodadvances.2017007112
Published: 2017
Includes: Supplemental data
Journal Articles

Inotuzumab ozogamicin in adults with relapsed or refractory CD22-positive acute lymphoblastic leukemia: a phase 1/2 study

Free
Clinical Trials & Observations
Daniel J. DeAngelo, Wendy Stock, Anthony S. Stein, Andrei Shustov, Michaela Liedtke, Charles A. Schiffer, Erik Vandendries, Katherine Liau, Revathi Ananthakrishnan, Joseph Boni, A. Douglas Laird, Luke Fostvedt, Hagop M. Kantarjian, Anjali S. Advani
Journal: Blood Advances
Blood Adv (2017) 1 (15): 1167–1180.
https://doi.org/10.1182/bloodadvances.2016001925
Published: 2017
Includes: Supplemental data