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Journal Articles

LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα

Kensaku Kohrogi, Shinjiro Hino, Akihisa Sakamoto, Kotaro Anan, Ryuta Takase, Hirotaka Araki, Yuko Hino, Kazutaka Araki, Tetsuya Sato, Kimitoshi Nakamura, Mitsuyoshi Nakao
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2305–2318.
https://doi.org/10.1182/bloodadvances.2020003521
Published: 2021
Includes: Supplemental data
Journal Articles

Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia

Pablo Iglesias, Ann-Christin Puller, Marcos Seoane, Michael Spohn, Sabine Raasch, Marianne Klokow, Jürgen Müller, Lia Burkhardt, Daniela Indenbirken, Martin A. Horstmann
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1209–1223.
https://doi.org/10.1182/bloodadvances.2020001844
Published: 2021
Includes: Supplemental data
Journal Articles

EVI1 and GATA2 misexpression induced by inv(3)(q21q26) contribute to megakaryocyte-lineage skewing and leukemogenesis

Ayaka Yamaoka, Mikiko Suzuki, Saori Katayama, Daiki Orihara, James Douglas Engel, Masayuki Yamamoto
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1722–1736.
https://doi.org/10.1182/bloodadvances.2019000978
Published: 2020
Includes: Supplemental data
Journal Articles

Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia

Haydar Çelik, Katherine E. Lindblad, Bogdan Popescu, Gege Gui, Meghali Goswami, Janet Valdez, Christin DeStefano, Catherine Lai, Julie Thompson, Jack Y. Ghannam, Giovanna Fantoni, Angélique Biancotto, Julián Candia, Foo Cheung, Gauthaman Sukumar, Clifton L. Dalgard, Richard H. Smith, Andre Larochelle, Laura W. Dillon, Christopher S. Hourigan
Journal: Blood Advances
Blood Adv (2020) 4 (2): 367–379.
https://doi.org/10.1182/bloodadvances.2019001124
Published: 2020
Includes: Supplemental data
Journal Articles

An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1); RUNX1-RUNX1T1

Sayer Al-Harbi, Mahmoud Aljurf, Mohamad Mohty, Fahad Almohareb, Syed Osman Ali Ahmed
Journal: Blood Advances
Blood Adv (2020) 4 (1): 229–238.
https://doi.org/10.1182/bloodadvances.2019000168
Published: 2020
Journal Articles

The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A -rearranged leukemia

Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4252–4263.
https://doi.org/10.1182/bloodadvances.2019032029
Published: 2019
Includes: Supplemental data
Journal Articles

KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis

Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Mohamed Rizk, Shuhei Kurosawa, Atsunori Saraya, Takashi Kondo, Emiko Sakaida, Chiaki Nakaseko, Koutaro Yokote, Haruhiko Koseki, Atsushi Iwama
Journal: Blood Advances
Blood Adv (2019) 3 (17): 2537–2549.
https://doi.org/10.1182/bloodadvances.2018028522
Published: 2019
Includes: Supplemental data
Journal Articles

The efficiency of murine MLL-ENL–driven leukemia initiation changes with age and peaks during neonatal development

Theresa Okeyo-Owuor, Yanan Li, Riddhi M. Patel, Wei Yang, Emily B. Casey, Andrew S. Cluster, Shaina N. Porter, David Bryder, Jeffrey A. Magee
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2388–2399.
https://doi.org/10.1182/bloodadvances.2019000554
Published: 2019
Includes: Supplemental data
Journal Articles

Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials

Yueh-Chwen Hsu, Tsung-Chih Chen, Chien-Chin Lin, Chang-Tsu Yuan, Chia-Lang Hsu, Hsin-An Hou, Chein-Jun Kao, Po-Han Chuang, Yu-Ren Chen, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2355–2367.
https://doi.org/10.1182/bloodadvances.2019000391
Published: 2019
Includes: Supplemental data
Journal Articles

Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia

Jesus Izaguirre-Carbonell, Luke Christiansen, Robert Burns, Jesse Schmitz, Chenxuan Li, Rebekah L. Mokry, Theresa Bluemn, Yongwei Zheng, Jian Shen, Karen-Sue Carlson, Sridhar Rao, Demin Wang, Nan Zhu
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1499–1511.
https://doi.org/10.1182/bloodadvances.2018026054
Published: 2019
Includes: Supplemental data
Journal Articles

Par-4 overexpression impedes leukemogenesis in the Eµ-TCL1 leukemia model through downregulation of NF-κB signaling

J. T. Greene, Rajeswaran Mani, Rahul Ramaswamy, Frank Frissora, Max Yano, Kevan Zapolnik, Bonnie Harrington, Ronni Wasmuth, Minh Tran, Xiaokui Mo, Mary McKenna, Vivek M. Rangnekar, John C. Byrd, Subbarao Bondada, Natarajan Muthusamy
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1255–1266.
https://doi.org/10.1182/bloodadvances.2018025973
Published: 2019
Includes: Supplemental data
Journal Articles

The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo

Xiaoling Wan, Lulu Liu, Peipei Zhou, Xinhui Hui, Qiaomei He, Fangfang Yu, Wei Zhang, Xiaodan Ding, Xiujie Yuan, Na Zhang, Yingxi Zhao, Ruihong Zhu, Yuanhua Liu, Pei Hao, Johan Auwerx, Xianmin Song, Qibin Leng, Yan Zhang
Journal: Blood Advances
Blood Adv (2019) 3 (4): 644–657.
https://doi.org/10.1182/bloodadvances.2018022756
Published: 2019
Includes: Supplemental data
Journal Articles

RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLs

Mylène Gerritsen, Guoqiang Yi, Esther Tijchon, Jorren Kuster, Jan Jacob Schuringa, Joost H. A. Martens, Edo Vellenga
Journal: Blood Advances
Blood Adv (2019) 3 (3): 320–332.
https://doi.org/10.1182/bloodadvances.2018024422
Published: 2019
Includes: Supplemental data
Journal Articles

Defining the epigenetic status of blood cells using a cyanine-based fluorescent probe for PRMT1

Hairui Su, Chiao-Wang Sun, Szu-Mam Liu, Xin He, Hao Hu, Kevin M. Pawlik, Tim M. Townes, Xiaosi Han, Christopher A. Klug, Maged Henary, Yabing Chen, Ling Li, Y. George Zheng, Xinyang Zhao
Journal: Blood Advances
Blood Adv (2018) 2 (21): 2829–2836.
https://doi.org/10.1182/bloodadvances.2018020727
Published: 2018
Includes: Supplemental data
Journal Articles

Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B

Carolina R. Batista, Michelle Lim, Anne-Sophie Laramée, Faisal Abu-Sardanah, Li S. Xu, Rajon Hossain, Gillian I. Bell, David A. Hess, Rodney P. DeKoter
Journal: Blood Advances
Blood Adv (2018) 2 (21): 2798–2810.
https://doi.org/10.1182/bloodadvances.2018019950
Published: 2018
Includes: Supplemental data
Journal Articles

Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia

Coline Gaillard, Sangeetha Surianarayanan, Trevor Bentley, Matthew R. Warr, Briana Fitch, Huimin Geng, Emmanuelle Passegué, Hugues de Thé, Scott C. Kogan
Journal: Blood Advances
Blood Adv (2018) 2 (19): 2462–2466.
https://doi.org/10.1182/bloodadvances.2018018929
Published: 2018
Includes: Supplemental data
Journal Articles

Myeloid leukemia factor 1 stabilizes tumor suppressor C/EBPα to prevent Trib1-driven acute myeloid leukemia

Ikuko Nakamae, Jun-ya Kato, Takashi Yokoyama, Hidenori Ito, Noriko Yoneda-Kato
Journal: Blood Advances
Blood Adv (2017) 1 (20): 1682–1693.
https://doi.org/10.1182/bloodadvances.2017007054
Published: 2017
Journal Articles

Paradoxical enhancement of leukemogenesis in acute myeloid leukemia with moderately attenuated RUNX1 expressions

Ken Morita, Shintaro Maeda, Kensho Suzuki, Hiroki Kiyose, Junichi Taniguchi, Pu Paul Liu, Hiroshi Sugiyama, Souichi Adachi, Yasuhiko Kamikubo
Journal: Blood Advances
Blood Adv (2017) 1 (18): 1440–1451.
https://doi.org/10.1182/bloodadvances.2017007591
Published: 2017
Includes: Supplemental data