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Journal Articles

Enhanced self-renewal of human long-term hematopoietic stem cells by a sulfamoyl benzoate derivative targeting p18 INK4C

Yinghui Li, Wenshan Zhang, Yu Zhang, Yahui Ding, Ming Yang, Mei He, Xiaolei Liu, Jiali Gu, Shiqi Xu, Zhiwei Feng, Yafang Li, Jingjing Yin, Huier Gao, Henan Song, Hui Xu, Chaoqun Wang, Qing Ji, Shihui Ma, Wanzhu Yang, Weiping Yuan, Xiang-Qun Xie, Tao Cheng, Yingdai Gao
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3362–3372.
https://doi.org/10.1182/bloodadvances.2020004054
Published: 2021
Includes: Supplemental data
Journal Articles

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis

Derek C. H. Chan, Joshua Xu, Ana Vujovic, Nicholas Wong, Victor Gordon, Laura P. M. H. de Rooij, Steven Moreira, Cailin E. Joyce, Jose La Rose, María-José Sandí, Bradley W. Doble, Carl D. Novina, Robert K. Rottapel, Kristin J. Hope
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3120–3133.
https://doi.org/10.1182/bloodadvances.2020002539
Published: 2021
Includes: Supplemental data
Journal Articles

Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish

Emanuele Gioacchino, Cansu Koyunlar, Joke Zink, Hans de Looper, Madelon de Jong, Tomasz Dobrzycki, Christopher B. Mahony, Remco Hoogenboezem, Dennis Bosch, Paulina M. H. van Strien, Martin E. van Royen, Pim J. French, Eric Bindels, Kirsten J. Gussinklo, Rui Monteiro, Ivo P. Touw, Emma de Pater
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2687–2700.
https://doi.org/10.1182/bloodadvances.2020002993
Published: 2021
Includes: Supplemental data
Journal Articles

Using mitochondrial activity to select for potent human hematopoietic stem cells

Jiajing Qiu, Jana Gjini, Tasleem Arif, Kateri Moore, Miao Lin, Saghi Ghaffari
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1605–1616.
https://doi.org/10.1182/bloodadvances.2020003658
Published: 2021
Includes: Supplemental data
Journal Articles

Autophagy is dispensable for the maintenance of hematopoietic stem cells in neonates

Michihiro Hashimoto, Terumasa Umemoto, Ayako Nakamura-Ishizu, Takayoshi Matsumura, Tomomasa Yokomizo, Maiko Sezaki, Hitoshi Takizawa, Toshio Suda
Journal: Blood Advances
Blood Adv (2021) 5 (6): 1594–1604.
https://doi.org/10.1182/bloodadvances.2020002410
Published: 2021
Includes: Supplemental data
Journal Articles

Haploidentical age-adapted myeloablative transplant and regulatory and effector T cells for acute myeloid leukemia

Clinical Trials & Observations
Antonio Pierini, Loredana Ruggeri, Alessandra Carotti, Franca Falzetti, Simonetta Saldi, Adelmo Terenzi, Claudio Zucchetti, Gianluca Ingrosso, Tiziana Zei, Roberta Iacucci Ostini, Sara Piccinelli, Samanta Bonato, Sara Tricarico, Antonella Mancusi, Sara Ciardelli, Roberto Limongello, Mara Merluzzi, Mauro Di Ianni, Rita Tognellini, Olivia Minelli, Cristina Mecucci, Maria Paola Martelli, Brunangelo Falini, Massimo Fabrizio Martelli, Cynthia Aristei, Andrea Velardi
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1199–1208.
https://doi.org/10.1182/bloodadvances.2020003739
Published: 2021
Includes: Supplemental data
Journal Articles

JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells

Hannah Lawson, Catarina Sepulveda, Louie N. van de Lagemaat, Jozef Durko, Melania Barile, Andrea Tavosanis, Elise Georges, Alena Shmakova, Penny Timms, Roderick N. Carter, Lewis Allen, Joana Campos, Milica Vukovic, Amelie V. Guitart, Peter Giles, Marie O’Shea, Douglas Vernimmen, Nicholas M. Morton, Neil P. Rodrigues, Berthold Göttgens, Christopher J. Schofield, Andreas Lengeling, Dónal O’Carroll, Kamil R. Kranc
Journal: Blood Advances
Blood Adv (2021) 5 (3): 889–899.
https://doi.org/10.1182/bloodadvances.2020002702
Published: 2021
Includes: Supplemental data
Journal Articles

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation

Antonio Maglitto, Samanta A. Mariani, Emma de Pater, Carmen Rodriguez-Seoane, Chris S. Vink, Xianhua Piao, Mari-Liis Lukke, Elaine Dzierzak
Journal: Blood Advances
Blood Adv (2021) 5 (3): 829–842.
https://doi.org/10.1182/bloodadvances.2020003693
Published: 2021
Includes: Supplemental data
Journal Articles

Inflammation-driven activation of JAK/STAT signaling reversibly accelerates acute myeloid leukemia in vitro

Jan Habbel, Lucas Arnold, Yiyang Chen, Michael Möllmann, Kirsten Bruderek, Sven Brandau, Ulrich Dührsen, Maher Hanoun
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3000–3010.
https://doi.org/10.1182/bloodadvances.2019001292
Published: 2020
Includes: Supplemental data
Journal Articles

Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status

Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Yasuhito Suehara, Kota Fukumoto, Yaeko Nakajima-Takagi, Hirotaka Matsui, Takayasu Kato, Hideharu Muto, Tatsuhiro Sakamoto, Manabu Kusakabe, Yasuhito Nannya, Hideki Makishima, Hiroo Ueno, Ryunosuke Saiki, Seishi Ogawa, Kenichi Chiba, Yuichi Shiraishi, Satoru Miyano, Enguerran Mouly, Olivier A. Bernard, Toshiya Inaba, Haruhiko Koseki, Atsushi Iwama, Shigeru Chiba
Journal: Blood Advances
Blood Adv (2020) 4 (5): 845–854.
https://doi.org/10.1182/bloodadvances.2019001324
Published: 2020
Includes: Supplemental data
Journal Articles

A 4-gene leukemic stem cell score can independently predict the prognosis of myelodysplastic syndrome patients

Clinical Trials & Observations
Yu-Hung Wang, Chien-Chin Lin, Chi-Yuan Yao, Chia-Lang Hsu, Hsin-An Hou, Cheng-Hong Tsai, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood Advances
Blood Adv (2020) 4 (4): 644–654.
https://doi.org/10.1182/bloodadvances.2019001185
Published: 2020
Includes: Supplemental data
Journal Articles

Non-del(5q) myelodysplastic syndromes–associated loci detected by SNP-array genome-wide association meta-analysis

Kathy L. McGraw, Chia-Ho Cheng, Y. Ann Chen, Hsin-An Hou, Björn Nilsson, Giulio Genovese, Thomas Cluzeau, Andrea Pellagatti, Bartlomiej P. Przychodzen, Mar Mallo, Leonor Arenillas, Azim Mohamedali, Lionel Adès, David A. Sallman, Eric Padron, Lubomir Sokol, Chimene Moreilhon, Sophie Raynaud, Hwei-Fang Tien, Jacqueline Boultwood, Benjamin L. Ebert, Francesc Sole, Pierre Fenaux, Ghulam J. Mufti, Jaroslaw P. Maciejewski, Peter A. Kanetsky, Alan F. List
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3579–3589.
https://doi.org/10.1182/bloodadvances.2019000922
Published: 2019
Includes: Supplemental data
Journal Articles

High-level protein production in erythroid cells derived from in vivo transduced hematopoietic stem cells

Hongjie Wang, Zhinan Liu, Chang Li, Sucheol Gil, Thalia Papayannopoulou, Christopher B. Doering, André Lieber
Journal: Blood Advances
Blood Adv (2019) 3 (19): 2883–2894.
https://doi.org/10.1182/bloodadvances.2019000706
Published: 2019
Includes: Supplemental data
Journal Articles

Phf6-null hematopoietic stem cells have enhanced self-renewal capacity and oncogenic potentials

Yueh-Chwen Hsu, Tsung-Chih Chen, Chien-Chin Lin, Chang-Tsu Yuan, Chia-Lang Hsu, Hsin-An Hou, Chein-Jun Kao, Po-Han Chuang, Yu-Ren Chen, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2355–2367.
https://doi.org/10.1182/bloodadvances.2019000391
Published: 2019
Includes: Supplemental data
Journal Articles

High mitochondrial mass is associated with reconstitution capacity and quiescence of hematopoietic stem cells

Yuji Takihara, Ayako Nakamura-Ishizu, Darren Qiancheng Tan, Masahiro Fukuda, Takayoshi Matsumura, Mitsuhiro Endoh, Yuichiro Arima, Desmond Wai Loon Chin, Terumasa Umemoto, Michihiro Hashimoto, Hidenobu Mizuno, Toshio Suda
Journal: Blood Advances
Blood Adv (2019) 3 (15): 2323–2327.
https://doi.org/10.1182/bloodadvances.2019032169
Published: 2019
Includes: Supplemental data
Journal Articles

In vivo dynamics of human hematopoietic stem cells: novel concepts and future directions

Serena Scala, Alessandro Aiuti
Journal: Blood Advances
Blood Adv (2019) 3 (12): 1916–1924.
https://doi.org/10.1182/bloodadvances.2019000039
Published: 2019
Journal Articles

CRISPR genome editing of murine hematopoietic stem cells to create Npm1-Alk causes ALK + lymphoma after transplantation

Soumya Sundara Rajan, Lingxiao Li, Mercedes F. Kweh, Kranthi Kunkalla, Amit Dipak Amin, Nitin K. Agarwal, Francisco Vega, Jonathan H. Schatz
Journal: Blood Advances
Blood Adv (2019) 3 (12): 1788–1794.
https://doi.org/10.1182/bloodadvances.2018025247
Published: 2019
Includes: Supplemental data
Journal Articles

Enhanced labile plasma iron in hematopoietic stem cell transplanted patients promotes Aspergillus outgrowth

Clinical Trials & Observations
Verena Petzer, Martin Wermke, Piotr Tymoszuk, Dominik Wolf, Markus Seifert, Rıdvan Ovaçin, Sylvia Berger, Dorothea Orth-Höller, Lorin Loacker, Günter Weiss, Hubertus Haas, Uwe Platzbecker, Igor Theurl
Journal: Blood Advances
Blood Adv (2019) 3 (11): 1695–1700.
https://doi.org/10.1182/bloodadvances.2019000043
Published: 2019
Includes: Supplemental data
Journal Articles

Plerixafor alone for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells

Clinical Trials & Observations
Yi-Bin Chen, Jennifer Le-Rademacher, Ruta Brazauskas, Deidre M. Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, Michael Craig, Mitchell E. Horwitz, Andrew S. Artz, Brian L. McClune, Hugo F. Fernandez, Hien Kim Duong, Hati Kobusingye, Mandi Proue, Rebecca J. Drexler, Mary M. Horowitz, Bronwen E. Shaw, John P. Miller, Sakura Hosoba, Edmund K. Waller, Steven M. Devine
Journal: Blood Advances
Blood Adv (2019) 3 (6): 875–883.
https://doi.org/10.1182/bloodadvances.2018027599
Published: 2019
Includes: Supplemental data
Journal Articles

Daily light-and-darkness onset regulates mouse hematopoietic stem cells

Karin Golan, Tsvee Lapidot
Journal: Blood Advances
Blood Adv (2019) 3 (4): 704.
https://doi.org/10.1182/bloodadvances.2018027722
Published: 2019
Includes: Supplemental data