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Journal Articles

IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB– and caspase-8–dependent mechanisms

Liang Zhou, Yu Zhang, Mark B. Meads, Yun Dai, Yanxia Ning, Xiaoyan Hu, Lin Li, Kanika Sharma, Jewel Nkwocha, Rebecca Parker, Danny Bui, Jacquelyn McCarter, Lora Kramer, Cullen Purcell, Praneeth R. Sudalagunta, Rafael R. Canevarolo, Maria D. Coelho Siqueira Silva, Gabriel De Avila, Raghunandan Reddy Alugubelli, Ariosto S. Silva, Maciej Kmeiciak, Andrea Ferreira-Gonzalez, Kenneth H. Shain, Steven Grant
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3776–3788.
https://doi.org/10.1182/bloodadvances.2020003597
Published: 2021
Includes: Supplemental data
Journal Articles

Increased levels of NETosis in myeloproliferative neoplasms are not linked to thrombotic events

Clinical Trials & Observations
Stefan Schmidt, Dimitri Daniliants, Elisabeth Hiller, Eberhard Gunsilius, Dominik Wolf, Clemens Feistritzer
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3515–3527.
https://doi.org/10.1182/bloodadvances.2020004061
Published: 2021
Includes: Supplemental data
Journal Articles

G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death

Eva De Smedt, Julie Devin, Catharina Muylaert, Nicolas Robert, Guilhem Requirand, Philip Vlummens, Laure Vincent, Guillaume Cartron, Ken Maes, Jerome Moreaux, Elke De Bruyne
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2325–2338.
https://doi.org/10.1182/bloodadvances.2020003217
Published: 2021
Includes: Supplemental data
Journal Articles

The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma

Brittany C. Lipchick, Adam Utley, Zhannan Han, Sudha Moparthy, Dong Hyun Yun, Anna Bianchi-Smiraglia, David W. Wolff, Emily Fink, Liang Liu, Cristina M. Furdui, Jingyun Lee, Kelvin P. Lee, Mikhail A. Nikiforov
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1933–1946.
https://doi.org/10.1182/bloodadvances.2020002578
Published: 2021
Includes: Supplemental data
Journal Articles

Antileukemic efficacy of a potent artemisinin combined with sorafenib and venetoclax

Blake S. Moses, Samantha McCullough, Jennifer M. Fox, Bryan T. Mott, Søren M. Bentzen, MinJung Kim, Jeffrey W. Tyner, Rena G. Lapidus, Ashkan Emadi, Michelle A. Rudek, Tami J. Kingsbury, Curt I. Civin
Journal: Blood Advances
Blood Adv (2021) 5 (3): 711–724.
https://doi.org/10.1182/bloodadvances.2020003429
Published: 2021
Includes: Supplemental data
Journal Articles

Thioridazine requires calcium influx to induce MLL-AF6 –rearranged AML cell death

Claudia Tregnago, Ambra Da Ros, Elena Porcù, Maddalena Benetton, Manuela Simonato, Luca Simula, Giulia Borella, Katia Polato, Sonia Minuzzo, Giulia Borile, Paola Cogo, Silvia Campello, Alessandro Massi, Romeo Romagnoli, Barbara Buldini, Franco Locatelli, Martina Pigazzi
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4417–4429.
https://doi.org/10.1182/bloodadvances.2020002001
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia

Anthony Quagliano, Anilkumar Gopalakrishnapillai, E. Anders Kolb, Sonali P. Barwe
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4393–4405.
https://doi.org/10.1182/bloodadvances.2020001592
Published: 2020
Includes: Supplemental data
Journal Articles

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

Timon A. Bloedjes, Guus de Wilde, Chiel Maas, Eric Eldering, Richard J. Bende, Carel J. M. van Noesel, Steven T. Pals, Marcel Spaargaren, Jeroen E. J. Guikema
Journal: Blood Advances
Blood Adv (2020) 4 (17): 4151–4164.
https://doi.org/10.1182/bloodadvances.2019001393
Published: 2020
Includes: Supplemental data
Journal Articles

Retinoic acid synergizes with the unfolded protein response and oxidative stress to induce cell death in FLT3-ITD + AML

Silvia Masciarelli, Ernestina Capuano, Tiziana Ottone, Mariadomenica Divona, Serena Lavorgna, Francesca Liccardo, Martyna Śniegocka, Serena Travaglini, Nelida I. Noguera, Alessandra Picardi, Vincenzo Petrozza, Alessandro Fatica, Luca Tamagnone, Maria Teresa Voso, Francesco Lo Coco, Francesco Fazi
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4155–4160.
https://doi.org/10.1182/bloodadvances.2019000540
Published: 2019
Includes: Supplemental data
Journal Articles

Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells

Laura M. Bystrom, Daniel P. Bezerra, Hsiao-Ting Hsu, Hongliang Zong, Luis A. Lara-Martínez, Jeanne P. De Leon, Megan Emmanuel, David Méry, Sara Gardenghi, Duane Hassane, Catherine C. Neto, Susanna Cunningham-Rundles, Michael W. Becker, Stefano Rivella, Monica L. Guzman
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3261–3265.
https://doi.org/10.1182/bloodadvances.2018026633
Published: 2019
Includes: Supplemental data
Journal Articles

TAK1 inhibition subverts the osteoclastogenic action of TRAIL while potentiating its antimyeloma effects

Hirofumi Tenshin, Jumpei Teramachi, Asuka Oda, Ryota Amachi, Masahiro Hiasa, Ariunzaya Bat-Erdene, Keiichiro Watanabe, Masami Iwasa, Takeshi Harada, Shiro Fujii, Kumiko Kagawa, Kimiko Sogabe, Shingen Nakamura, Hirokazu Miki, Kiyoe Kurahashi, Sumiko Yoshida, Kenichi Aihara, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto, Masahiro Abe
Journal: Blood Advances
Blood Adv (2017) 1 (24): 2124–2137.
https://doi.org/10.1182/bloodadvances.2017008813
Published: 2017
Includes: Supplemental data