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Volume 3, Issue 18

September 24 2019

In this Issue

EXCEPTIONAL CASE REPORTS
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
TRANSPLANTATION
ERRATUM

EXCEPTIONAL CASE REPORTS

Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

Victoria V. Grunwald,Marcus Hentrich,Xaver Schiel,Annika Dufour,Stephanie Schneider,Michaela Neusser,Marion Subklewe,Michael Fiegl,Wolfgang Hiddemann,Karsten Spiekermann,Maja Rothenberg-Thurley,Klaus H. Metzeler

View Articletitled, Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

Supplemental data

Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies

Angela C. Weyand,Veronica H. Flood,Jordan A. Shavit,Steven W. Pipe

View Articletitled, Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies

GENE THERAPY

Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice

Chunyan Gao,Jocelyn A. Schroeder,Feng Xue,Weiqing Jing,Yuanhua Cai,Amelia Scheck,Saravanan Subramaniam,Sridhar Rao,Hartmut Weiler,Agnieszka Czechowicz,Qizhen Shi

View Articletitled, Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice

Supplemental data

HEMATOPOIESIS AND STEM CELLS

MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways

Minyoung Youn,Haigen Huang,Cheng Chen,Sharon Kam,Mark C. Wilkes,Hee-Don Chae,Kunju J. Sridhar,Peter L. Greenberg,Bertil Glader,Anupama Narla,Shuo Lin,Kathleen M. Sakamoto

View Articletitled, MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways

Supplemental data

LYMPHOID NEOPLASIA

Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6

Tekla Järviaho,Benedicte Bang,Vasilios Zachariadis,Fulya Taylan,Jukka Moilanen,Merja Möttönen,C. I. Edvard Smith,Arja Harila-Saari,Riitta Niinimäki,Ann Nordgren

View Articletitled, Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting <em>ETV6</em>

Supplemental data

MYELOID NEOPLASIA

Representation of therapy-related myelodysplastic syndrome in clinical trials over the past 20 years

Uma Borate,Brianna A. Norris,Abby Statler,Rongwei Fu,Taylor Bucy,Mikkael A. Sekeres

View Articletitled, Representation of therapy-related myelodysplastic syndrome in clinical trials over the past 20 years

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation

Jonathan M. Tsai,Maia Shoham,Nathaniel B. Fernhoff,Benson M. George,Kristopher D. Marjon,Melissa N. McCracken,Kevin S. Kao,Rahul Sinha,Anne Kathrin Volkmer,Masanori Miyanishi,Jun Seita,Yuval Rinkevich,Irving L. Weissman

View Articletitled, Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation

Supplemental data

TRANSPLANTATION

Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients

Swati Naik,Caridad A. Martinez,Bilal Omer,Ghadir Sasa,Khaled Yassine,Carl E. Allen,Kala Kamdar,Robert Orth,Mengfen Wu,Kathryn Leung,Stephen Gottschalk,Malcolm K. Brenner,Helen E. Heslop,Robert A. Krance

View Articletitled, Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients

Breath analysis in gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation

Betty K. Hamilton,Lisa A. Rybicki,David Grove,Christina Ferraro,Jamie Starn,Brittany Hodgeman,Jamie Elberson,Victoria Winslow,Donna Corrigan,Aaron T. Gerds,Rabi Hanna,Matt E. Kalaycio,Ronald M. Sobecks,Navneet S. Majhail,Raed A. Dweik

View Articletitled, Breath analysis in gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation

Comparison of characteristics and outcomes of late acute and NIH chronic GVHD between Japanese and white patients

Yoshihiro Inamoto,Jennifer White,Reiko Ito,Paul J. Martin,Giancarlo Fatobene,Ayumu Ito,Takashi Tanaka,Saiko Kurosawa,Sung-Won Kim,Merav Bar,Mohamed L. Sorror,Brenda M. Sandmaier,Stephanie J. Lee,Takahiro Fukuda,Mary E. D. Flowers

View Articletitled, Comparison of characteristics and outcomes of late acute and NIH chronic GVHD between Japanese and white patients

ERRATUM

Manasanch EE, Han G, Mathur R, et al. A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. Blood Adv. 2019;3(15):2400-2408.

View Articletitled, Manasanch EE, Han G, Mathur R, et al. A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. <em>Blood Adv.</em> 2019;3(15):2400-2408.

Cover Image

Cover Image

COVER FIGURE
Circulating neutrophils (shown in green) infiltrate into sites of peritoneal adhesions following injury, form neutrophil extracellular traps (shown in blue), and exacerbate adhesion severity. Depletion of circulating neutrophils prior to injury prevents adhesion formation. See the article by Tsai et al.
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CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation

The combination of Asp519Val/Glu665Val and Lys1813Ala mutations in FVIII markedly increases coagulation potential

Multimodal mechanisms of pathogenic variants in the signal peptide of FIX leading to hemophilia B

Affimer reagents as tool molecules to modulate platelet GPVI-ligand interactions and specifically bind GPVI dimer

Deletion of pyruvate dehydrogenase kinases reduces susceptibility to deep vein thrombosis in mice

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EXCEPTIONAL CASE REPORTS

Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies

GENE THERAPY

Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice

HEMATOPOIESIS AND STEM CELLS

MMP9 inhibition increases erythropoiesis in RPS14-deficient del(5q) MDS models through suppression of TGF-β pathways

LYMPHOID NEOPLASIA

Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6

MYELOID NEOPLASIA

Representation of therapy-related myelodysplastic syndrome in clinical trials over the past 20 years

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Neutrophil and monocyte kinetics play critical roles in mouse peritoneal adhesion formation

TRANSPLANTATION

Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients

Breath analysis in gastrointestinal graft-versus-host disease after allogeneic hematopoietic cell transplantation

Comparison of characteristics and outcomes of late acute and NIH chronic GVHD between Japanese and white patients

ERRATUM

Manasanch EE, Han G, Mathur R, et al. A pilot study of pembrolizumab in smoldering myeloma: report of the clinical, immune, and genomic analysis. Blood Adv. 2019;3(15):2400-2408.

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American Society of Hematology

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EXCEPTIONAL CASE REPORTS

GENE THERAPY

HEMATOPOIESIS AND STEM CELLS

LYMPHOID NEOPLASIA

MYELOID NEOPLASIA

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

TRANSPLANTATION

ERRATUM

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American Society of Hematology

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