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Volume 2, Issue 5

March 13 2018

In this Issue

STIMULUS REPORT
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
ERRATUM

STIMULUS REPORT

Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model

Robert A. French,Benjamin J. Samelson-Jones,Glenn P. Niemeyer,Clinton D. Lothrop, Jr,Elizabeth P. Merricks,Timothy C. Nichols,Valder R. Arruda

View Articletitled, Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model

Supplemental data

REVIEW ARTICLE

Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease

Hitomi Hosoya,Jeffrey Levine,Peter Abt,David Henry,David L. Porter,Saar Gill

View Articletitled, Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease

CLINICAL TRIALS AND OBSERVATIONS

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine
Clinical Trials & Observations

Raphaelle Fanciullino,Laure Farnault,Mélanie Donnette,Diane-Charlotte Imbs,Catherine Roche,Geoffroy Venton,Yael Berda-Haddad,Vadim Ivanov,Joseph Ciccolini,L’Houcine Ouafik,Bruno Lacarelle,Regis Costello

View Articletitled, CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine

Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study
Clinical Trials & Observations

Andreas K. Øvlisen,Anders Oest,Mette D. Bendtsen,John Bæch,Preben Johansen,Line S. Lynggaard,Ingolf Mølle,Thomas B. Mortensen,Duruta Weber,Gideon Ertner,Claudia Schöllkopf,Jesper Q. Thomassen,Ove Juul Nielsen,Lene Sofie Granfeldt Østgård,Martin Bøgsted,Karen Dybkær,Hans E. Johnsen,Marianne T. Severinsen

View Articletitled, Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study

HEMATOPOIESIS AND STEM CELLS

Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm

Pingnan Xiao,Monika Dolinska,Lakshmi Sandhow,Makoto Kondo,Anne-Sofie Johansson,Thibault Bouderlique,Ying Zhao,Xidan Li,Marios Dimitriou,George Z. Rassidakis,Eva Hellström-Lindberg,Nagahiro Minato,Julian Walfridsson,David T. Scadden,Mikael Sigvardsson,Hong Qian

View Articletitled, Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm

Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

A novel method to generate T-cell receptor–deficient chimeric antigen receptor T cells

Takahiro Kamiya,Desmond Wong,Yi Tian Png,Dario Campana

View Articletitled, A novel method to generate T-cell receptor–deficient chimeric antigen receptor T cells

Supplemental data

LYMPHOID NEOPLASIA

Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia
Clinical Trials & Observations

Thai Hoa Tran,Marian H. Harris,Jonathan V. Nguyen,Traci M. Blonquist,Kristen E. Stevenson,Eileen Stonerock,Barbara L. Asselin,Uma H. Athale,Luis A. Clavell,Peter D. Cole,Kara M. Kelly,Caroline Laverdiere,Jean-Marie Leclerc,Bruno Michon,Marshall A. Schorin,Jennifer J. G. Welch,Shalini C. Reshmi,Donna S. Neuberg,Stephen E. Sallan,Mignon L. Loh,Lewis B. Silverman

View Articletitled, Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia

MYELOID NEOPLASIA

Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas

Alexandra Nagy,Aparna Bhaduri,Nahid Shahmarvand,Jahanbanoo Shahryari,James L. Zehnder,Roger A. Warnke,Tariq Mughal,Siraj Ali,Robert S. Ohgami

View Articletitled, Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas

Supplemental data

IMiD compounds affect CD34⁺ cell fate and maturation via CRBN-induced IKZF1 degradation

Shirong Li,Jing Fu,Hui Wang,Huihui Ma,Xiaoming Xu,Yong-Guang Yang,Shixian Deng,Markus Y. Mapara,Suzanne Lentzsch

View Articletitled, IMiD compounds affect CD34+ cell fate and maturation via CRBN-induced IKZF1 degradation

Supplemental data

RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice

Ken Morita,Chieko Tokushige,Shintaro Maeda,Hiroki Kiyose,Mina Noura,Atsushi Iwai,Maya Yamada,Gengo Kashiwazaki,Junichi Taniguchi,Toshikazu Bando,Masahiro Hirata,Tatsuki R. Kataoka,Tatsutoshi Nakahata,Souichi Adachi,Hiroshi Sugiyama,Yasuhiko Kamikubo

View Articletitled, RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice

Supplemental data

PLATELETS AND THROMBOPOIESIS

Platelet TGF-β1 deficiency decreases liver fibrosis in a mouse model of liver injury

Shahrouz Ghafoory,Rohan Varshney,Tyler Robison,Karim Kouzbari,Sean Woolington,Brennah Murphy,Lijun Xia,Jasimuddin Ahamed

View Articletitled, Platelet TGF-β1 deficiency decreases liver fibrosis in a mouse model of liver injury

Supplemental data

THROMBOSIS AND HEMOSTASIS

Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors

Alexey Dementiev,Abel Silva,Calvin Yee,Zhe Li,Michael T. Flavin,Hing Sham,James R. Partridge

View Articletitled, Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors

Supplemental data

TRANSPLANTATION

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation
Clinical Trials & Observations

Coco de Koning,Julie-Anne Gabelich,Jurgen Langenhorst,Rick Admiraal,Jurgen Kuball,Jaap Jan Boelens,Stefan Nierkens

View Articletitled, Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation

Supplemental data

ERRATUM

Francica JR, Zak DE, Linde C, et al. Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs. Blood Adv. 2017;1(25):2329-2342.

View Articletitled, Francica JR, Zak DE, Linde C, et al. Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs. Blood Adv. 2017;1(25):2329-2342.

Cover Image

Cover Image

COVER FIGURE
CD34⁺ cells stably transduced with a lentivirus carrying the control short hairpin RNA were treated with pomalidomide (1 μM) for 6 hours. The cells were then stained for IKZF1 (red) or green fluorescent protein (green), using DAPI (4′,6-diamidino-2-phenylindole) for nuclear counterstaining (blue). The localization of IKZF1 was observed with a Leica microscope (original magnification ×200). See the article by Li et al.
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Table of Contents

STIMULUS REPORT

Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model

REVIEW ARTICLE

Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease

CLINICAL TRIALS AND OBSERVATIONS

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine
Clinical Trials & Observations

Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study
Clinical Trials & Observations

HEMATOPOIESIS AND STEM CELLS

Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm

IMMUNOBIOLOGY AND IMMUNOTHERAPY

A novel method to generate T-cell receptor–deficient chimeric antigen receptor T cells

LYMPHOID NEOPLASIA

Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia
Clinical Trials & Observations

MYELOID NEOPLASIA

Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas

IMiD compounds affect CD34⁺ cell fate and maturation via CRBN-induced IKZF1 degradation

RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice

PLATELETS AND THROMBOPOIESIS

Platelet TGF-β1 deficiency decreases liver fibrosis in a mouse model of liver injury

THROMBOSIS AND HEMOSTASIS

Structures of human plasma β–factor XIIa cocrystallized with potent inhibitors

TRANSPLANTATION

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation
Clinical Trials & Observations

ERRATUM

Francica JR, Zak DE, Linde C, et al. Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs. Blood Adv. 2017;1(25):2329-2342.

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ASH Publications

American Society of Hematology

Issue Archive

Table of Contents

STIMULUS REPORT

REVIEW ARTICLE

CLINICAL TRIALS AND OBSERVATIONS

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine Clinical Trials & Observations

Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study Clinical Trials & Observations

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY AND IMMUNOTHERAPY

LYMPHOID NEOPLASIA

Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia Clinical Trials & Observations

MYELOID NEOPLASIA

PLATELETS AND THROMBOPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation Clinical Trials & Observations

ERRATUM

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

CDA as a predictive marker for life-threatening toxicities in patients with AML treated with cytarabine
Clinical Trials & Observations

Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study
Clinical Trials & Observations

Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia
Clinical Trials & Observations

Filgrastim enhances T-cell clearance by antithymocyte globulin exposure after unrelated cord blood transplantation
Clinical Trials & Observations