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David T. Scadden
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Journal Articles

Clearing and replacing tissue-resident myeloid cells with an anti-CD45 antibody–drug conjugate

Karin Gustafsson, Catherine Rhee, Vanessa Frodermann, Elizabeth W. Scadden, Dan Li, Yoshiko Iwamoto, Rahul Palchaudhuri, Sharon L. Hyzy, Anthony E. Boitano, Matthias Nahrendorf, David T. Scadden
Journal: Blood Advances
Blood Adv (2023) 7 (22): 6964–6973.
https://doi.org/10.1182/bloodadvances.2023010561
Published: 2023
Includes: Supplemental data
Journal Articles

The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression

Youmna S. Kfoury, Fei Ji, Esha Jain, Michael Mazzola, Giulia Schiroli, Ani Papazian, Francois Mercier, David B. Sykes, Anna Kiem, Mark Randolph, Laura M. Calvi, Omar Abdel-Wahab, Ruslan I. Sadreyev, David T. Scadden
Journal: Blood Advances
Blood Adv (2023) 7 (21): 6608–6623.
https://doi.org/10.1182/bloodadvances.2022008268
Published: 2023
Includes: Supplemental data
Journal Articles

In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies

Francois E. Mercier, Jiantao Shi, David B. Sykes, Toshihiko Oki, Maja Jankovic, Cheuk Him Man, Youmna S. Kfoury, Elizabeth Miller, Shutao He, Alexander Zhu, Radovan Vasic, John Doench, Alexandre Orthwein, Franziska Michor, David T. Scadden
Journal: Blood Advances
Blood Adv (2022) 6 (17): 5072–5084.
https://doi.org/10.1182/bloodadvances.2022007250
Published: 2022
Includes: Supplemental data
Journal Articles

Cell interactions in the bone marrow microenvironment affecting myeloid malignancies

Konstantinos D. Kokkaliaris, David T. Scadden
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3795–3803.
https://doi.org/10.1182/bloodadvances.2020002127
Published: 2020
Journal Articles

Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm

Pingnan Xiao, Monika Dolinska, Lakshmi Sandhow, Makoto Kondo, Anne-Sofie Johansson, Thibault Bouderlique, Ying Zhao, Xidan Li, Marios Dimitriou, George Z. Rassidakis, Eva Hellström-Lindberg, Nagahiro Minato, Julian Walfridsson, David T. Scadden, Mikael Sigvardsson, Hong Qian
Journal: Blood Advances
Blood Adv (2018) 2 (5): 534–548.
https://doi.org/10.1182/bloodadvances.2017013599
Published: 2018
Includes: Supplemental data