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David B. Sykes
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Journal Articles

DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

Amy N. Sexauer, Gabriela Alexe, Karin Gustafsson, Elizabeth Zanetakos, Jelena Milosevic, Mary Ayres, Varsha Gandhi, Yana Pikman, Kimberly Stegmaier, David B. Sykes
Journal: Blood Advances
Blood Adv (2023) 7 (21): 6685–6701.
https://doi.org/10.1182/bloodadvances.2023010337
Published: 2023
Includes: Supplemental data
Journal Articles

The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression

Youmna S. Kfoury, Fei Ji, Esha Jain, Michael Mazzola, Giulia Schiroli, Ani Papazian, Francois Mercier, David B. Sykes, Anna Kiem, Mark Randolph, Laura M. Calvi, Omar Abdel-Wahab, Ruslan I. Sadreyev, David T. Scadden
Journal: Blood Advances
Blood Adv (2023) 7 (21): 6608–6623.
https://doi.org/10.1182/bloodadvances.2022008268
Published: 2023
Includes: Supplemental data
Journal Articles

In vivo genome-wide CRISPR screening in murine acute myeloid leukemia uncovers microenvironmental dependencies

Francois E. Mercier, Jiantao Shi, David B. Sykes, Toshihiko Oki, Maja Jankovic, Cheuk Him Man, Youmna S. Kfoury, Elizabeth Miller, Shutao He, Alexander Zhu, Radovan Vasic, John Doench, Alexandre Orthwein, Franziska Michor, David T. Scadden
Journal: Blood Advances
Blood Adv (2022) 6 (17): 5072–5084.
https://doi.org/10.1182/bloodadvances.2022007250
Published: 2022
Includes: Supplemental data
Journal Articles

A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis

Jihee Sohn, Jelena Milosevic, Thomas Brouse, Najihah Aziz, Jenna Elkhoury, Suya Wang, Alexander Hauschild, Nick van Gastel, Murat Cetinbas, Sara F. Tufa, Douglas R. Keene, Ruslan I. Sadreyev, William T. Pu, David B. Sykes
Journal: Blood Advances
Blood Adv (2022) 6 (8): 2557–2577.
https://doi.org/10.1182/bloodadvances.2021005720
Published: 2022
Includes: Supplemental data
Journal Articles

A cryptic imatinib-sensitive G3BP1-PDGFRB rearrangement in a myeloid neoplasm with eosinophilia

Clinical Trials & Observations
Max Jan, Daniel E. Grinshpun, Julian A. Villalba, Paola Dal Cin, David B. Sykes, A. John Iafrate, Benjamin L. Ebert, Gabriela S. Hobbs, Valentina Nardi
Journal: Blood Advances
Blood Adv (2020) 4 (3): 445–448.
https://doi.org/10.1182/bloodadvances.2019001182
Published: 2020
Journal Articles

A modern reassessment of glycoprotein-specific direct platelet autoantibody testing in immune thrombocytopenia

Hanny Al-Samkari, Rachel P. Rosovsky, Rebecca S. Karp Leaf, David B. Smith, Katayoon Goodarzi, Annemarie E. Fogerty, David B. Sykes, David J. Kuter
Journal: Blood Advances
Blood Adv (2019) 4 (1): 9–18.
https://doi.org/10.1182/bloodadvances.2019000868
Published: 2019
Includes: Supplemental data