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Issue Archive

Volume 2, Issue 3
February 13 2018
Issue Cover

Table of Contents

BLOOD ADVANCES TALK

Challenges facing the benign hematology physician-scientist workforce: identifying issues of recruitment and retention
Elizabeth Soffer,William Keith Hoots
View Articletitled, Challenges facing the benign hematology physician-scientist workforce: identifying issues of recruitment and retention
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Professional illustration by Patrick Lane, ScEYEnce Studios

Comparative effectiveness of direct oral anticoagulants and warfarin in patients with cancer and atrial fibrillation
Clinical Trials & Observations
Surbhi Shah,Faye L. Norby,Yvonne H. Datta,Pamela L. Lutsey,Richard F. MacLehose,Lin Y. Chen,Alvaro Alonso
View Articletitled, Comparative effectiveness of direct oral anticoagulants and warfarin in patients with cancer and atrial fibrillation
Supplemental data
Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia
Clinical Trials & Observations
Peter G. Maslak,Tao Dao,Yvette Bernal,Suzanne M. Chanel,Rong Zhang,Mark Frattini,Todd Rosenblat,Joseph G. Jurcic,Renier J. Brentjens,Maria E. Arcila,Raajit Rampal,Jae H. Park,Dan Douer,Laura Katz,Nicholas Sarlis,Martin S. Tallman,David A. Scheinberg
View Articletitled, Phase 2 trial of a multivalent WT1 peptide vaccine (galinpepimut-S) in acute myeloid leukemia
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists
Christopher T. Petersen,Mojibade Hassan,Anna B. Morris,Jasmin Jeffery,Kunhee Lee,Neera Jagirdar,Ashley D. Staton,Sunil S. Raikar,Harold T. Spencer,Todd Sulchek,Christopher R. Flowers,Edmund K. Waller
View Articletitled, Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists
Supplemental data
The immunoglobulin heavy chain 3′ regulatory region superenhancer controls mouse B1 B-cell fate and late VDJ repertoire diversity
Nour Ghazzaui,Hussein Issaoui,Alexis Saintamand,Christelle Oblet,Claire Carrion,Yves Denizot
View Articletitled, The immunoglobulin heavy chain 3′ regulatory region superenhancer controls mouse B1 B-cell fate and late VDJ repertoire diversity
Supplemental data
A primary role for human central memory cells in tissue immunosurveillance
Ahmed Gehad,Jessica E. Teague,Tiago R. Matos,Victor Huang,Chao Yang,Rei Watanabe,John T. O’Malley,Cornelia L. Trimble,Thomas S. Kupper,Rachael A. Clark
View Articletitled, A primary role for human central memory cells in tissue immunosurveillance
Supplemental data

LYMPHOID NEOPLASIA

Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy
Clinical Trials & Observations
Jean-François Spinella,Chantal Richer,Pauline Cassart,Manon Ouimet,Jasmine Healy,Daniel Sinnett
View Articletitled, Mutational dynamics of early and late relapsed childhood ALL: rapid clonal expansion and long-term dormancy
Supplemental data

MYELOID NEOPLASIA

Variability of PD-L1 expression in mastocytosis
Clinical Trials & Observations
Ellen W. Hatch,Mary Beth Geeze,Cheyenne Martin,Mohamed E. Salama,Karin Hartmann,Gregor Eisenwort,Katharina Blatt,Peter Valent,Jason Gotlib,Ji-Hyun Lee,Lu Chen,Heather H. Ward,Diane S. Lidke,Tracy I. George
View Articletitled, Variability of PD-L1 expression in mastocytosis
Supplemental data
C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia
Justin Loke,Paulynn Suyin Chin,Peter Keane,Anna Pickin,Salam A. Assi,Anetta Ptasinska,Maria Rosaria Imperato,Peter N. Cockerill,Constanze Bonifer
View Articletitled, C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Biocompatible coupling of therapeutic fusion proteins to human erythrocytes
Carlos H. Villa,Daniel C. Pan,Ian H. Johnston,Colin F. Greineder,Landis R. Walsh,Elizabeth D. Hood,Douglas B. Cines,Mortimer Poncz,Don L. Siegel,Vladimir R. Muzykantov
View Articletitled, Biocompatible coupling of therapeutic fusion proteins to human erythrocytes
Supplemental data
g(HbF): a genetic model of fetal hemoglobin in sickle cell disease
Clinical Trials & Observations
Kate Gardner,Tony Fulford,Nicholas Silver,Helen Rooks,Nikolaos Angelis,Marlene Allman,Siana Nkya,Julie Makani,Jo Howard,Rachel Kesse-Adu,David C. Rees,Sara Stuart-Smith,Tullie Yeghen,Moji Awogbade,Raphael Z. Sangeda,Josephine Mgaya,Hamel Patel,Stephen Newhouse,Stephan Menzel,Swee Lay Thein
View Articletitled, <em>g(HbF)</em>: a genetic model of fetal hemoglobin in sickle cell disease
Supplemental data
Prevalence and risk factors for venous thromboembolism in children with sickle cell disease: an administrative database study
Clinical Trials & Observations
Riten Kumar,Joseph Stanek,Susan Creary,Amy Dunn,Sarah H. O’Brien
View Articletitled, Prevalence and risk factors for venous thromboembolism in children with sickle cell disease: an administrative database study

THROMBOSIS AND HEMOSTASIS

Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI
Samantha J. Montague,Céline Delierneux,Christelle Lecut,Nathalie Layios,Robert J. Dinsdale,Christine S.-M. Lee,Natalie S. Poulter,Robert K. Andrews,Peter Hampson,Christopher M. Wearn,Nathalie Maes,Jonathan Bishop,Amy Bamford,Chris Gardiner,Woei Ming Lee,Tariq Iqbal,Naiem Moiemen,Steve P. Watson,Cécile Oury,Paul Harrison,Elizabeth E. Gardiner
View Articletitled, Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI
Supplemental data

TRANSPLANTATION

Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ+/CD19+-depleted grafts
Clinical Trials & Observations
Javid Gaziev,Antonella Isgrò,Pietro Sodani,Katia Paciaroni,Gioia De Angelis,Marco Marziali,Michela Ribersani,Cecilia Alfieri,Alessandro Lanti,Tiziana Galluccio,Gaspare Adorno,Marco Andreani
View Articletitled, Haploidentical HSCT for hemoglobinopathies: improved outcomes with TCRαβ<sup>+</sup>/CD19<sup>+</sup>-depleted grafts
Effect of donor characteristics on haploidentical transplantation with posttransplantation cyclophosphamide
Clinical Trials & Observations
Shannon R. McCurdy,Mei-Jie Zhang,Andrew St. Martin,Monzr M. Al Malki,Asad Bashey,Sameh Gaballa,Daniel A. Keesler,Mehdi Hamadani,Maxim Norkin,Miguel-Angel Perales,Ran Reshef,Vanderson Rocha,Rizwan Romee,Melhem Solh,Alvaro Urbano-Ispizua,Edmund K. Waller,Ephraim J. Fuchs,Mary Eapen
View Articletitled, Effect of donor characteristics on haploidentical transplantation with posttransplantation cyclophosphamide
Supplemental data
  • Cover Image

    Cover Image

    issue cover

    COVER FIGURE
    A subset of mast cells coexpresses PD-L1 in the spleen from a patient with mast cell leukemia. Tryptase is red, PD-L1 is light green, and cell nuclei are blue (DAPI [4′,6-diamidino-2-phenylindole] stain). See the article by Hatch et al.

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