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Journal Articles

VEXAS syndrome

Peter C. Grayson, Bhavisha A. Patel, Neal S. Young
Journal: Blood
Blood (2021) 137 (26): 3591–3594.
https://doi.org/10.1182/blood.2021011455
Published: 2021
Journal Articles

Plasmablasts derive from CD23 – activated B cells after the extinction of IL-4/STAT6 signaling and IRF4 induction

Amandine Pignarre, Fabrice Chatonnet, Gersende Caron, Marion Haas, Fabienne Desmots, Thierry Fest
Journal: Blood
Blood (2021) 137 (9): 1166–1180.
https://doi.org/10.1182/blood.2020005083
Published: 2021
Includes: Supplemental data
Journal Articles

LUBAC accelerates B-cell lymphomagenesis by conferring resistance to genotoxic stress on B cells

Tomoyasu Jo, Momoko Nishikori, Yasunori Kogure, Hiroshi Arima, Katsuhiro Sasaki, Yoshiteru Sasaki, Tomoko Nakagawa, Fumie Iwai, Shuji Momose, Aki Shiraishi, Hiroshi Kiyonari, Noritaka Kagaya, Tetsuo Onuki, Kazuo Shin-ya, Minoru Yoshida, Keisuke Kataoka, Seishi Ogawa, Kazuhiro Iwai, Akifumi Takaori-Kondo
Journal: Blood
Blood (2020) 136 (6): 684–697.
https://doi.org/10.1182/blood.2019002654
Published: 2020
Includes: Supplemental data
Journal Articles

A master erythroid regulator gets its own GPS

Lily Jun-shen Huang, James J. Bieker
Journal: Blood
Blood (2020) 135 (25): 2209–2210.
https://doi.org/10.1182/blood.2020005882
Published: 2020
Journal Articles

Wdr26 regulates nuclear condensation in developing erythroblasts

Ru Zhen, Chingyee Moo, Zhenzhen Zhao, Mengying Chen, He Feng, Xiaojun Zheng, Liang Zhang, Jiahai Shi, Caiyong Chen
Journal: Blood
Blood (2020) 135 (3): 208–219.
https://doi.org/10.1182/blood.2019002165
Published: 2020
Includes: Supplemental data
Journal Articles

Preclinical Validation of Ubiquitin Receptor PSMD4 As Therapeutic Target in Multiple Myeloma

Yan Song, PhD, Ting DU, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4403.
https://doi.org/10.1182/blood-2019-122952
Published: 2019
Journal Articles

Targeted Protein Degradation of BTK As a Unique Therapeutic Approach for B Cell Malignancies

Aileen Kelly, PhD, Daniel W Robbins, May Tan, Austin Tenn-McClellan, Joel McIntosh, Jeffrey Wu, Zef Konst, Daisuke Kato, Luz Perez, Jennifer Tung, Anna Kolobova, Timothy Ingallinera, Jenny McKinnell, Dahlia Weiss, Mark Noviski, Jordan Ye, Ge Peng, Mario Cardozo, Jeff Mihalic, Steve Basham, Ryan Rountree, Dane E Karr, Neil Bence, Christoph W Zapf, Arthur T Sands
Journal: Blood
Blood (2019) 134 (Supplement_1): 3805.
https://doi.org/10.1182/blood-2019-129262
Published: 2019
Journal Articles

Aurora Kinase a/MDM2-Mediated SETD2 Loss of Function in Chronic Myeloid Leukemia Patients in Blast Crisis Can be Therapeutically Targeted Inducing Apoptotic Cell Death in a Caspase-Dependent Way

Manuela Mancini, PhD, Sara De Santis, Dr, Cecilia Monaldi, Dr, Luana Bavaro, Dr, Margherita Martelli, Dr, Gabriele Gugliotta, MD PhD, Fausto Castagnetti, MD PhD, Gianantonio Rosti, MD, Maria Chiara Fontana, PhD, Samantha Bruno, Dr, Elisa Dan, PhD, Barbara Sinigaglia, Dr, Alessandra Iurlo, MD PhD, Nicola Orofino, MD, Elisabetta Abruzzese, MD, Marzia Salvucci, MD, Patrizia Pregno, Antonella Gozzini, MD, Monica Crugnola, MD, Francesco Albano, MD, Massimiliano Bonifacio, MD, Elisabetta Calistri, MD, Mario Tiribelli, Gianni Binotto, MD, Annalisa Imovilli, Elena Trabacchi, MD, Sara Galimberti, MD PhD, Claudia Baratè, Elena Tenti, Michele Baccarani, MD, Giovanni Martinelli, MD, Michele Cavo, Simona Soverini, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4142.
https://doi.org/10.1182/blood-2019-126500
Published: 2019
Journal Articles

A Multi-Center Dose-Finding Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Fimepinostat (CUDC-907) in Combination with Venetoclax in Patients with Relapsed/Refractory (R/R) Lymphoma

Anas Younes, MD, Connie Lee Batlevi, MD PhD, Jonathon B. Cohen, MDMS, Sven de Vos, MD PhD, Daniel J. Landsburg, MD, Zaw Win Myint, MD, Krish Patel, MD, Tycel J. Phillips, MD, Sonali M. Smith, MD, Jason R. Westin, MD, Anna W Ma, MS, Dena Grayson, MD PhD, Reinhard von Roemeling, MD, Stefan K. Barta, MD MRCP, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4104.
https://doi.org/10.1182/blood-2019-128857
Published: 2019
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019
Journal Articles

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

Scott R Best, BS, Vi Lam, Nur Bruss, BS, Taylor Hashiguchi Rowland, BS, Adam S. Kittai, MD, Tingting Liu, Allison J Berger, PhD, Alexey Danilov, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4313.
https://doi.org/10.1182/blood-2019-123600
Published: 2019
Journal Articles

Single-Cell RNA-Seq to Assess Differential Responses to Tnfα in Human Hematopoietic Stem and Progenitor Cells in Myeloproliferative Neoplasm

Brianna Craver, MS, Quy Nguyen, Gajalakshmi Ramanathan, PhD, Angela G. Fleischman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2518.
https://doi.org/10.1182/blood-2019-123480
Published: 2019
Journal Articles

Role of Ubiquitin E3 Ligase UBR5 in B-Cell Development and Lymphoma

Tyler Gilbreath, B.S., Samantha Swenson, PhD, Shannon M. Buckley, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2794.
https://doi.org/10.1182/blood-2019-128747
Published: 2019
Journal Articles

FLT3 Is Sumoylated and Localizes to the Nucleus in Acute Myeloid Leukemia

Marisse Asong, MD MSc, Julhash Uddin Kazi, PhD, Lars Ronnstrand, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2733.
https://doi.org/10.1182/blood-2019-127914
Published: 2019
Journal Articles

Proteomic Analysis Identifies Mechanism(s) of Overcoming Bortezomib-Resistance Via Targeting Ubiquitin Receptor Rpn13

Ting Du, PhD, Yan Song, PhD, Arghya Ray, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3074.
https://doi.org/10.1182/blood-2019-130236
Published: 2019
Journal Articles

RFWD2 Induces Cellular Proliferation and Proteasome Inhibitor Resistance By Mediating p27 Ubiqutinaiton in Multiple Myeloma

Ye Yang, PhD, Mengjie Guo, Chunyan Gu
Journal: Blood
Blood (2019) 134 (Supplement_1): 3068.
https://doi.org/10.1182/blood-2019-127888
Published: 2019
Journal Articles

NF-κB-Dependent Activation of the Proteasome Components, PSMD1 and PSMD3, As a Mechanism of Resistance to Imatinib

Idaly Maria Olivas, BS, Joshua Lara, BS, Rebecca Ellwood, MS, Carme Ripoll Fiol, MS, Andres J Rubio, MS, Alfonso Enrique Bencomo, PhD, Mayra Alejandra Gonzalez, BS, Georgios Nteliopoulos, PhD, Alistair Reid, BSc, PhD, Dragana Milojkovic, MBBS, MD, Jane Apperley, MB, ChB, MD, Jamshid Sorouri Khorashad, MD PhD FRCPath, Anna M. Eiring, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2923.
https://doi.org/10.1182/blood-2019-126963
Published: 2019
Journal Articles

Blockade of Ubiquitin Receptor Rpn13 in Plasmacytoid Dendritic Cells Enhances Anti-Myeloma Immunity

Arghya Ray, PhD, Yan Song, PhD, Ting DU, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3098.
https://doi.org/10.1182/blood-2019-122901
Published: 2019
Journal Articles

Personalized Ubiquitination Signatures for Predicting Response to Proteasome Inhibitor-Based Therapy of MM Patients

Haim Tsubery, PhD, Lerman Gali, PhD, Kronenfeld Gali, MSc, Itamar Sela, PhD, Yifat Merbl, PhD, Ayelet Itzhaki-Alfia, PhD, Svetlana Trestman, MD, Yael C Cohen, MD, Irit Avivi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3371.
https://doi.org/10.1182/blood-2019-125274
Published: 2019
Journal Articles

Mechanisms of Proteasome Inhibitor Resistance Selected By Clonal Evolution in Multiple Myeloma

Larissa Haertle, PhD, Santiago Barrio, PhD, Michal Simicek, PhD, Umair Munawar, MSc, Ricardo Sanchez, PhD MD, Max Bittrich, MD, Matteo DaVia, MD, Cornelia Vogt, MSc, Nicola Giesen, MD, Andoni Garitano-Trojaola, PhD, Silvia Nerreter, Thorsten Stuehmer, PhD, Marc S. Raab, MD, Joaquin Martinez Lopez, MD PhD, Roman Hajek, MD, Hermann Einsele, MD, Leo Rasche, MD, Thomas Haaf, MD, Martin Kortüm, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4349.
https://doi.org/10.1182/blood-2019-130847
Published: 2019