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Journal Articles

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

Shok Ping Lim, Benedetta Costantini, Syed A. Mian, Pilar Perez Abellan, Shreyans Gandhi, Marc Martinez Llordella, Juan Jose Lozano, Rita Antunes dos Reis, Giovanni A. M. Povoleri, Thanos P. Mourikis, Ander Abarrategi, Linda Ariza-McNaughton, Susanne Heck, Jonathan M. Irish, Giovanna Lombardi, Judith C. W. Marsh, Dominique Bonnet, Shahram Kordasti, Ghulam J. Mufti

Blood (2020) 136 (7): 885–897.

https://doi.org/10.1182/blood.2019001347

Published: 2020

Includes: Supplemental data

Journal Articles

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

Shuichiro Takashima, MD PhD, Maria L. Martin, PhD, Suze A. Jansen, Ya-Yuan Fu, PhD, Anastasiya Egorova, Chen Liu, MD PhD, Richard Kolesnick, MD, Caroline A. Lindemans, MD, Alan M. Hanash, MD PhD

Blood (2019) 134 (Supplement_1): 585.

https://doi.org/10.1182/blood-2019-130811

Published: 2019

Journal Articles

15-PGDH Inhibition Mitigates Aplastic Anemia Severity

Julianne N. P. Smith, PhD, Folashade Otegbeye, MBBChir,MPH, Alvin Jogasuria, Sanford Markowitz, MD PhD, Amar Desai, PhD

Blood (2019) 134 (Supplement_1): 1220.

https://doi.org/10.1182/blood-2019-131353

Published: 2019

Journal Articles

Blockade of CD95/CD95L Death Signaling Enhances CAR T Cell Persistence and Antitumor Efficacy

Bailin He, PhD, Lei Wang, MD, Brigitte Neuber, Anita Schmitt, MD, Niclas Kneisel, PhD, Thomas Hoeger, PhD, Carsten Mueller-Tidow, MD, Michael Schmitt, MD, Susanne Hofmann, MD

Blood (2019) 134 (Supplement_1): 3226.

https://doi.org/10.1182/blood-2019-122833

Published: 2019

Journal Articles

Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance

Ryan N Rys, BSc, BA, Maanasa Venkataraman, MSc, Jibin Zeng, MSc, Koren Kathleen Mann, PhD, Nathalie Johnson, MD

Blood (2019) 134 (Supplement_1): 1520.

https://doi.org/10.1182/blood-2019-130602

Published: 2019

Journal Articles

Engineering CpG Deoxynucleotide-Conjugated Gold Nanoparticles for Enhanced Anti-Lymphoma Effects in an Immune Competent Lymphoma Model

Adam Yuh Lin, MD PhD, Jonathan Rink, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD

Blood (2019) 134 (Supplement_1): 1577.

https://doi.org/10.1182/blood-2019-125308

Published: 2019

Journal Articles

Galectin-9 from Bone Marrow Mesenchymal Stromal Cells Mediates Immunosuppression on Chimeric Antigen Receptor T Cells

Xinyi Teng, BS, Hao Zhang, MD, Zuyu Liang, MD, Mi Shao, MD, Xiujian Wang, MD, Lijuan Ding, MD, Jiazhen Cui, msc, Yongxian Hu, MD, He Huang, MD PhD

Blood (2019) 134 (Supplement_1): 5609.

https://doi.org/10.1182/blood-2019-131680

Published: 2019

Journal Articles

KIR Expression on in Vitro -Derived Natural Killer Cells Does Not Regulate Killing of Allogeneic Targets

Yunzu Michele Wang, MD, Huang Zhu, PhD, Alessa Ruiz-Cisneros, Naveen Heragu, BS, Eivind Heggernes Ask, Hanna Julie Hoel, Karl-Johan Malmberg, MD PhD, Dan S Kaufman, MD PhD

Blood (2018) 132 (Supplement 1): 3705.

https://doi.org/10.1182/blood-2018-99-117151

Published: 2018

Journal Articles

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Antonella Nai, PhD, Irene Artuso, MSc, Maria Rosa Lidonnici, PhD, Sandro Altamura, PhD, Giacomo Mandelli, PhD, Mariateresa Pettinato, MSc, Martina U. Muckenthaler, PhD, Laura Silvestri, PhD, Giuliana Ferrari, PhD, Clara Camaschella, MD

Blood (2018) 132 (Supplement 1): 3624.

https://doi.org/10.1182/blood-2018-99-115835

Published: 2018

Journal Articles

Notch Activation Rescues Exhaustion in CISH -Deleted Human iPSC-Derived Natural Killer Cells to Promote In Vivo Persistence and Enhance Anti-Tumor Activity

Huang Zhu, PhD, Robert Blum, Zhengming Wu, Andres Bahena, Hanna Julie Hoel, Eivind Heggernes Ask, Kun-Liang Guan, PhD, Karl-Johan Malmberg, MD PhD, Dan S Kaufman, MDPhD

Blood (2018) 132 (Supplement 1): 1279.

https://doi.org/10.1182/blood-2018-99-112791

Published: 2018

Journal Articles

Senescent Mesenchymal Stem Cells Present at the Early Post Allogeneic Hematopoietic Stem Cell Transplantation Period Are Associated with an Increased Incidence of Acute Graft-Versus Host Disease and Increased Plasma Levels of Fas Ligand

Daniel Rivera, MD, Lika Osugui, PhD, Sandra Muntion, PhD, Miguel Alcoceba, PhD, Concepcion Rodriguez, Rebeca Ortega, Natalia Espinosa, MD, Ana Gomez de la Torre, Ana Rico, Miriam López-Parra, MD, Alba Redondo, MD, Eva Villarón, Félix López Cadenas, MD, Silvia Preciado, Maria Díez-Campelo, Lucía López Corral, MD, Marcos González, MD PhD, Dolores Caballero, MD, Fermin Sanchez-Guijo, MD PhD

Blood (2018) 132 (Supplement 1): 2116.

https://doi.org/10.1182/blood-2018-99-115363

Published: 2018

Journal Articles

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

Kristina Maas-Bauer, MD, Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Arielle Wenokur, Furqan Fazal, PhD, Neeraja Kambham, MD, Jessica Ribado, Melissa Mavers, MD PhD, Jeanette Baker, Ami S. Bhatt, MD PhD, Howard Y. Chang, MD PhD, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 475.

https://doi.org/10.1182/blood-2018-99-113673

Published: 2018

Journal Articles

Brief Ex Vivo Incubation with Fas Ligand Selectively Depletes Alloreactive T Cells and Antigen Presenting Cells from Stem Cell Grafts

Hilit Levy-Barazany, PhD, Liat Pinkas, PhD, Galina Rodionov, Nitzan Marelly, Michal Tzadok, Hila Wildbaum, Tamar Katz, PhD, Ronit Bakimer, PhD, Shai Yarkoni, MD PhD, Amnon Peled, Jerry Stein, MD, Tsila Zuckerman, MD

Blood (2018) 132 (Supplement 1): 2033.

https://doi.org/10.1182/blood-2018-99-117920

Published: 2018

Journal Articles

NOTCH Inhibition Separates GVL from GVHD Via Modulating Host Dendritic Cell and Donor T-Cell Activation

Xiaodan Luo, Lihua Xu, Yangqiu Li, Huo Tan

Blood (2017) 130 (Supplement 1): 5451.

https://doi.org/10.1182/blood.V130.Suppl_1.5451.5451

Published: 2017

Journal Articles

Effective and Ineffective Samples of Mesenchymal Multipotent Stromal Cells Used for Acute Graft-Versus-Host Disease Prophylaxis after Allogeneic Bone Marrow Transplantation Differ in the Expression Level of HLA-DR When Co-Cultured with Activated Lymphocytes

Nataliya Petinati, PhD MD, Nikolay M. Kapranov, Yuliya O Davydova, Alexey Bigildeev, PhD, Natalia Sats, PhD, Irina Shipounova, PhD, Nina Drize, PhD, Irina V. Galtseva, MD PhD, Larisa A. Kuzmina, MD PhD, Elena N. Parovichnikova, MD PhD, Valeriy G. Savchenko

Blood (2017) 130 (Supplement 1): 5494.

https://doi.org/10.1182/blood.V130.Suppl_1.5494.5494

Published: 2017

Journal Articles

NKG2D Negatively Regulates CD4 T Cells in Allo-Response in Mice

Mengmeng Zhang, MD, Yongxia Wu, PhD MD, David Bastian, Hung D Nguyen, PhD, Supinya Iamsawat, MSc, Anusara Daenthanasanmak, Fangping Chen, MD PhD, Xue-Zhong Yu, MD MS

Blood (2017) 130 (Supplement 1): 2279.

https://doi.org/10.1182/blood.V130.Suppl_1.2279.2279

Published: 2017

Journal Articles

Results of a Non-Interventional Clinical Trial of Apograft — a Novel Technology for GvHD Prevention

Jerry Stein, MD, Tsila Zuckerman, MD, Yuval Baar, Hila Wildbaum, Tamar Katz, Michal Perl-Yaffe, Limor Horev-Azaria, Shai Yarkoni, MD PhD, Amotz Nechushtan, Galina Rodionov, Liron Gez, Michal Rosenzwaig, Anastasia Rodin, Yaron Pereg, John F DiPersio, MD PhD, Jacob M. Rowe, MD, Isaac Yaniv, MD

Blood (2017) 130 (Supplement 1): 4445.

https://doi.org/10.1182/blood.V130.Suppl_1.4445.4445

Published: 2017

Journal Articles

CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL

Alexandra Aronin, PhD, Liat Ben Gigi-Tamir, PhD, Efi Makdasi, PhD, Shira Amsili, PhD, Shlomi Ben David, Ortal Avraham, Yehudith Jitka Sagiv, Yosi Meir Gozlan, PhD, Noam Shani, PhD, Michal Dranitzki Elhalel, MD MSc

Blood (2017) 130 (Supplement 1): 4107.

https://doi.org/10.1182/blood.V130.Suppl_1.4107.4107

Published: 2017

Journal Articles

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Benedetta Costantini, MD, Syed A Mian, PhD, Shok Ping Lim, PhD, Frederic Toulza, PhD, Stephen Orr, PhD, Pilar Perez-Abellan, MSc, Ander Abarrategi, PhD, Farzin Farzaneh, PhD, Dominique Bonnet, PhD, Judith Marsh, MD, Shahram Kordasti, MD PhD, Ghulam Mufti, DM, FRCP, FRCPath

Blood (2017) 130 (Supplement 1): 2450.

https://doi.org/10.1182/blood.V130.Suppl_1.2450.2450

Published: 2017

Journal Articles

Enhanced Spontaneous Anti-Tumor Cytotoxicity of Natural Killer Cells in Cutaneous T-Cell Lymphoma Patients

Bethany L Mundy-Bosse, PhD, Nathan Denlinger, MS, DO, Susan Huang, MD, Li Chen, Hsiaoyin Mao, David Kline, Eric McLaughlin, Youssef Youssef, Karen Young, Gerard Lozanski, MD, Aharon G. Freud, MD PhD, Pierluigi Porcu, MD, Basem M. William, MD, Michael A. Caligiuri, MD, Anjali Mishra, PhD

Blood (2017) 130 (Supplement 1): 2753.

https://doi.org/10.1182/blood.V130.Suppl_1.2753.2753

Published: 2017

NARROW

Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction

T-Cell Derived Interferon Gamma Directly Targets Intestinal Epithelium to Induce Stem Cell Apoptosis in GI Gvhd

15-PGDH Inhibition Mitigates Aplastic Anemia Severity

Blockade of CD95/CD95L Death Signaling Enhances CAR T Cell Persistence and Antitumor Efficacy

Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance

Engineering CpG Deoxynucleotide-Conjugated Gold Nanoparticles for Enhanced Anti-Lymphoma Effects in an Immune Competent Lymphoma Model

Galectin-9 from Bone Marrow Mesenchymal Stromal Cells Mediates Immunosuppression on Chimeric Antigen Receptor T Cells

KIR Expression on in Vitro -Derived Natural Killer Cells Does Not Regulate Killing of Allogeneic Targets

Exploring the Mechanisms of Thalassemic Erythropoiesis Improvement Caused By Bone Marrow Tfr2 Deletion

Notch Activation Rescues Exhaustion in CISH -Deleted Human iPSC-Derived Natural Killer Cells to Promote In Vivo Persistence and Enhance Anti-Tumor Activity

Senescent Mesenchymal Stem Cells Present at the Early Post Allogeneic Hematopoietic Stem Cell Transplantation Period Are Associated with an Increased Incidence of Acute Graft-Versus Host Disease and Increased Plasma Levels of Fas Ligand

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

Brief Ex Vivo Incubation with Fas Ligand Selectively Depletes Alloreactive T Cells and Antigen Presenting Cells from Stem Cell Grafts

NOTCH Inhibition Separates GVL from GVHD Via Modulating Host Dendritic Cell and Donor T-Cell Activation

Effective and Ineffective Samples of Mesenchymal Multipotent Stromal Cells Used for Acute Graft-Versus-Host Disease Prophylaxis after Allogeneic Bone Marrow Transplantation Differ in the Expression Level of HLA-DR When Co-Cultured with Activated Lymphocytes

NKG2D Negatively Regulates CD4 T Cells in Allo-Response in Mice

Results of a Non-Interventional Clinical Trial of Apograft — a Novel Technology for GvHD Prevention

CTLA4-FasL, the Hexameric Targeted FasL Fusion Protein, As Potential Novel Treatment for DLBCL

Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia

Enhanced Spontaneous Anti-Tumor Cytotoxicity of Natural Killer Cells in Cutaneous T-Cell Lymphoma Patients

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