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Journal Articles

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

Jayakumar Vadakekolathu, PhD, Stephen Reeder, BSc, Clare Coveney, PhD, Sergio Rutella, MDPhDFRCPath

Blood (2019) 134 (Supplement_1): 2726.

https://doi.org/10.1182/blood-2019-124717

Published: 2019

Journal Articles

A Novel Combination of Drugs Which Target Both the Intrinsic and Extrinsic Apoptotic Pathways to Eliminate Myelofibrosis CD34+ Cells

Min Lu, PhD, Lijuan Xia, Ronald Hoffman, MD

Blood (2019) 134 (Supplement_1): 4201.

https://doi.org/10.1182/blood-2019-129017

Published: 2019

Journal Articles

Targeting CD38 high Acute Myeloid Leukaemia with "Affinity Optimized" Chimeric Antigen Receptor and Membrane Bound TRAIL Expressing Natural Killer Cells

Emma Nolan, BSc, Arwen Stikvoort, PhD, Mark Gurney, MD, Nutsa Burduli, BSc, Lucy Kirkham-McCarthy, MSc, John Daly, MSc, Niels W. C. J. Van De Donk, Tuna Mutis, MD PhD, Subhashis Sarkar, PhD, Michael E O'Dwyer, MD

Blood (2019) 134 (Supplement_1): 5536.

https://doi.org/10.1182/blood-2019-128605

Published: 2019

Journal Articles

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

Blood (2018) 132 (Supplement 1): 4334.

https://doi.org/10.1182/blood-2018-99-114507

Published: 2018

Journal Articles

Somatic PRAME Deletions Are Associated with Decreased Immunogenicity, Apoptosis Resistance and Poor Outcomes in Diffuse Large B-Cell Lymphoma

Katsuyoshi Takata, MD PhD, Daisuke Ennishi, MDPhD, Ali Bashashati, Saeed Saberi, Elena Viganò, PhD, Shannon Healy, PhD, Julie S Nielsen, Gianluca D' Antonio, Brad H Nelson, Sohrab P Shah, Joseph M Connors, Randy D. Gascoyne, MD, David W. Scott, PhDMD,FRACP,FRCPA, Christian Steidl, MD

Blood (2018) 132 (Supplement 1): 667.

https://doi.org/10.1182/blood-2018-99-113516

Published: 2018

Journal Articles

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

Malik Bisserier, Narendra Wajapeyee

Blood (2018) 131 (19): 2125–2137.

https://doi.org/10.1182/blood-2017-08-804344

Published: 2018

Includes: Supplemental data

Journal Articles

Potent Ex Vivo Anti-Tumor Activity in Relapsed Refractory Multiple Myeloma Using Novel DR5-Specific Antibodies with Enhanced Capacity to Form Hexamers upon Target Binding

Hilma J van der Horst, Marije B Overdijk, Esther CW Breij, Martine Chamuleau, MD PhD, Henk M Lokhorst, Tuna Mutis, PhD

Blood (2017) 130 (Supplement 1): 1835.

https://doi.org/10.1182/blood.V130.Suppl_1.1835.1835

Published: 2017

Journal Articles

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Mediates and Sustains NF-κb Constitutive Activation in LGL Leukemia Cells

Jun Yang, MD, Francis R Leblanc, PhD, Shubha Dighe, MS, Susan B. Nyland, PhD, David J. Feith, PhD, Thomas P. Loughran, Jr., MD

Blood (2016) 128 (22): 2762.

https://doi.org/10.1182/blood.V128.22.2762.2762

Published: 2016

Journal Articles

Genetic and Epigenetic Defects in the Autophagy Machinery in Myelodysplastic Syndromes

Valeria Visconte, PhD, Bartlomiej P Przychodzen, MSc, Steffan T. Nawrocki, PhD, Swapna Thota, MD, Kevin R. Kelly, MD PhD, Bhumika Patel, MD, Cassandra M. Hirsch, BSc, Hetty E. Carraway, MD MBA, Yvonne Parker, Daniel Lindner, Mikkael A. Sekeres, MD MS, Heesun J Rogers, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Jennifer S. Carew, PhD

Blood (2016) 128 (22): 4301.

https://doi.org/10.1182/blood.V128.22.4301.4301

Published: 2016

Journal Articles

Thioridazine Enhances TRAIL Cytotoxicity in Human Myeloid Leukemic Cells By up-Regulating DR5 and Modulating PI3K-AKT-NF-Kb Pathway

Yi Wang, Yangyi Bao, Leiming Xia, Liu Liu, Kunyuan Guo, Mingzhen Yang, MDPhD

Blood (2015) 126 (23): 4938.

https://doi.org/10.1182/blood.V126.23.4938.4938

Published: 2015

Journal Articles

Transcriptome Analysis of Erythroid Cells Cultured from Diamond Blackfan Anemia Patients with Ribosomal and GATA1 Mutations Reveals Dysregulation of Inflammatory Response Genes

Kelly O'Brien, PhD, Adrianna Vlachos, Stacie M. Anderson, Crystiana Tsujiura, Lionel Blanc, PhD, Eva Atsidaftos, MA, NIH Intramural Sequencing Center, Jason E. Farrar, MD, Steven R Ellis, PhD, Jeffrey Michael Lipton, MD PhD, David M. Bodine, PhD

Blood (2015) 126 (23): 3605.

https://doi.org/10.1182/blood.V126.23.3605.3605

Published: 2015

Journal Articles

Biomarkers of Cardiotoxicity Among Multiple Myeloma Patients Subsequently Treated with Proteasome Inhibitor Therapy

Nikoletta Lendvai, MDPhD, Sean Devlin, PhD, Minal Patel, BA, Kristina Marie Knapp, Daniel Ekman, Ida Grundberg, David J Chung, MDPhD, Hani Hassoun, MD, Guenther Koehne, MDPhD, Alexander M. Lesokhin, MD, Heather Landau, MD, Sergio A. Giralt, MD, Neha S Korde, MD, Ola Landgren, MD PhD

Blood (2015) 126 (23): 4257.

https://doi.org/10.1182/blood.V126.23.4257.4257

Published: 2015

Journal Articles

Upregulation of Interferon-Inducible and Damage Response Receptors in Chronic Graft-Versus-Host Disease

Frances T. Hakim, PhD, Sarfraz Memon, MD, Ping Jin, PhD, Matin M. Imanguli, DDS, MD, Najibah Rehman, MD, Xiao-Yi Yan, MS, Jeremy J. Rose, BA, Jacqueline W. Mays, DDS, PhD, Susan Dhamala, BA, Veena Kapoor, William Telford, PhD, David C. Halverson, MD, Kristin Baird, MD, Daniel H. Fowler, MD, David Stroncek, MD, Edward W. Cowen, MD MHSc, Steven Z. Pavletic, MD, Ronald E. Gress, MD

Blood (2015) 126 (23): 922.

https://doi.org/10.1182/blood.V126.23.922.922

Published: 2015

Journal Articles

Loss of Foxo3 Reduces Erythroblast Apoptosis and Enhances RBC Production in Beta-Thalassemic Mice

Raymond Liang, B.S., Genís Campreciós, PhD, Carolina L. Bigarella, PhD, Saghi Ghaffari, MD PhD

Blood (2015) 126 (23): 756.

https://doi.org/10.1182/blood.V126.23.756.756

Published: 2015

Journal Articles

Cflar Splicing SNP As Predictor of Chemo-Sensitivity to Anticancer Drugs

Lata Chauhan, PhD, Emilie J Bergsma, Jatinder K Lamba, PhD

Blood (2015) 126 (23): 2056.

https://doi.org/10.1182/blood.V126.23.2056.2056

Published: 2015

Journal Articles

Effects of Bone Marrow Infiltration By Multiple Myeloma on Erythropoiesis

Tamara K Moyo, MD PhD, Anass Bouchnita, MS, Nathalie Eymard, PhD, Vitaly Volpert, PhD, Mark J. Koury, MD

Blood (2015) 126 (23): 2143.

https://doi.org/10.1182/blood.V126.23.2143.2143

Published: 2015

Journal Articles

Melphalan Affects Genes Critical for Myeloma Survival, Homing, and Response to Cytokines and Chemokines

Shmuel Yaccoby, Joshua Epstein, DSc, Pingping Qu, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Christoph Heuck, MD, Faith E Davies, MD, Alan Mitchell, Antje Hoering, PhD, John Crowley, PhD, Bart Barlogie, MD PhD, Gareth J Morgan, MDPhD

Blood (2015) 126 (23): 1808.

https://doi.org/10.1182/blood.V126.23.1808.1808

Published: 2015

Journal Articles

Transiently Elevated AST/LDH Are Associated with Clinical Response to Recombinant Circularly Permuted TRAIL (CPT) Plus Thalidomide in Patients with Relapsed and/or Refractory Multiple Myeloma

Wenming Chen, MD, Peng Wei, PhD, Shifang Yang, PhD, Xiangjun Zheng, Lugui Qiu, MD, Jian Hou, MD PhD, Xuejun Zhang, MD, Zhao Wang, Xiaoyan Ke, MD PhD, Ling Pan, MDPhD, Hongyan Pang, PhD

Blood (2014) 124 (21): 3478.

https://doi.org/10.1182/blood.V124.21.3478.3478

Published: 2014

Journal Articles

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Amriti R. Lulla, Christina Leah B Kline, PhD, Liz J. Hernandez-Borrero, Varun Vijay Prabhu, Jessica M Wagner, David T. Dicker, Nathan G. Dolloff, PhD, Brian M Barth, PhD, Jeffrey J Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP

Blood (2014) 124 (21): 5224.

https://doi.org/10.1182/blood.V124.21.5224.5224

Published: 2014

Journal Articles

Potent In Vivo Anti-Tumor Activity Of Extracellular Vesicles Isolated From Genetically Engineered Primary Mesenchymal Stromal Cells Expressing The Trans-Membrane TNF-Related Apoptosis-Inducing Ligand (TRAIL)

Stefano Buttiglieri, PhD, Carmelo Carlo-Stella, MD, Tiziana Spatola, BiolSc, Roberta Pulito, BiolSc, Luigi Naldini, MD, PhD, Andrea Anichini, PhD, Michele Magni, MD, Arianna Giacomini, PhD, Corrado Tarella, MD, Alessandro M. Gianni, MD

Blood (2013) 122 (21): 1658.

https://doi.org/10.1182/blood.V122.21.1658.1658

Published: 2013

NARROW

Tipifarnib Modulates Interferon (IFN)-γ-Inducible Genes in Acute Myeloid Leukemia

A Novel Combination of Drugs Which Target Both the Intrinsic and Extrinsic Apoptotic Pathways to Eliminate Myelofibrosis CD34+ Cells

Targeting CD38 high Acute Myeloid Leukaemia with "Affinity Optimized" Chimeric Antigen Receptor and Membrane Bound TRAIL Expressing Natural Killer Cells

The Malignant Hemopoietic Clone of Triple Negative Patients with Myelofibrosis Shows in Vitro Functional Defects but Is Highly Responsive to the Pro-Survival Signals of Circulating Autologous Microvesicles

Somatic PRAME Deletions Are Associated with Decreased Immunogenicity, Apoptosis Resistance and Poor Outcomes in Diffuse Large B-Cell Lymphoma

Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas

Potent Ex Vivo Anti-Tumor Activity in Relapsed Refractory Multiple Myeloma Using Novel DR5-Specific Antibodies with Enhanced Capacity to Form Hexamers upon Target Binding

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Mediates and Sustains NF-κb Constitutive Activation in LGL Leukemia Cells

Genetic and Epigenetic Defects in the Autophagy Machinery in Myelodysplastic Syndromes

Thioridazine Enhances TRAIL Cytotoxicity in Human Myeloid Leukemic Cells By up-Regulating DR5 and Modulating PI3K-AKT-NF-Kb Pathway

Transcriptome Analysis of Erythroid Cells Cultured from Diamond Blackfan Anemia Patients with Ribosomal and GATA1 Mutations Reveals Dysregulation of Inflammatory Response Genes

Biomarkers of Cardiotoxicity Among Multiple Myeloma Patients Subsequently Treated with Proteasome Inhibitor Therapy

Upregulation of Interferon-Inducible and Damage Response Receptors in Chronic Graft-Versus-Host Disease

Loss of Foxo3 Reduces Erythroblast Apoptosis and Enhances RBC Production in Beta-Thalassemic Mice

Cflar Splicing SNP As Predictor of Chemo-Sensitivity to Anticancer Drugs

Effects of Bone Marrow Infiltration By Multiple Myeloma on Erythropoiesis

Melphalan Affects Genes Critical for Myeloma Survival, Homing, and Response to Cytokines and Chemokines

Transiently Elevated AST/LDH Are Associated with Clinical Response to Recombinant Circularly Permuted TRAIL (CPT) Plus Thalidomide in Patients with Relapsed and/or Refractory Multiple Myeloma

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Potent In Vivo Anti-Tumor Activity Of Extracellular Vesicles Isolated From Genetically Engineered Primary Mesenchymal Stromal Cells Expressing The Trans-Membrane TNF-Related Apoptosis-Inducing Ligand (TRAIL)

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American Society of Hematology

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American Society of Hematology

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