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Marije B Overdijk
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Journal Articles

Duohexabody-CD37, a Novel Bispecific Antibody with a Hexamerization-Enhancing Mutation Targeting CD37, Demonstrates Superior Complement-Dependent Cytotoxicity in Preclinical B-Cell Malignancy Models

Simone C. Oostindie, MSc, Hilma J. Van Der Horst, MSc, Marije B. Overdijk, PhD, Kristin Strumane, PhD, Sandra Verploegen, PhD, Margaret A. Lindorfer, PhD, Erica M. Cook, B.A., Martine E.D. Chamuleau, MD, Tuna Mutis, PhD, Janine Schuurman, PhD, A. Kate Sasser, PhD, Ronald P. Taylor, PhD, Paul W. H. I. Parren, PhD, Frank J. Beurskens, PhD, Esther C. W. Breij, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4170.
https://doi.org/10.1182/blood-2018-99-114723
Published: 2018
Journal Articles

Targeting CD37 in B-Cell Malignancies Using the Novel Therapeutic Duohexabody-CD37 Results in Efficient Killing of Tumor B-Cells Ex Vivo Via Complement-Dependent Cytotoxicity, Even in Relapsed and/or Refractory Patient Samples

Hilma J. Van Der Horst, MSc, Simone C. Oostindie, MSc, Saskia AGM Cillessen, MSc, Anne T Gelderloos, MSc, Marije B Overdijk, Martine E.D. Chamuleau, MD, Esther C. W. Breij, PhD, Tuna Mutis, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4179.
https://doi.org/10.1182/blood-2018-99-115886
Published: 2018
Journal Articles

Potent Ex Vivo Anti-Tumor Activity in Relapsed Refractory Multiple Myeloma Using Novel DR5-Specific Antibodies with Enhanced Capacity to Form Hexamers upon Target Binding

Hilma J van der Horst, Marije B Overdijk, Esther CW Breij, Martine Chamuleau, MD PhD, Henk M Lokhorst, Tuna Mutis, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1835.
https://doi.org/10.1182/blood.V130.Suppl_1.1835.1835
Published: 2017
Journal Articles

Direct in Vitro Comparison of Daratumumab with Surrogate Analogs of CD38 Antibodies MOR03087, SAR650984 and Ab79

Jeroen Lammerts van Bueren, PhD, Danielle Jakobs, Niels Kaldenhoven, Marcel Roza, Sanne Hiddingh, Joyce Meesters, Marleen Voorhorst, Elke Gresnigt, Luus Wiegman, Antonio Ortiz Buijsse, Grietje Andringa, Marije B. Overdijk, PhD, Parul Doshi, PhD, Kate Sasser, Michel de Weers, PhD, Paul W.H.I. Parren, PhD
Journal: Blood
Blood (2014) 124 (21): 3474.
https://doi.org/10.1182/blood.V124.21.3474.3474
Published: 2014
Journal Articles

Daratumumab, a Human CD38 Antibody Induces Apoptosis of Myeloma Tumor Cells Via Fc Receptor-Mediated Crosslinking.

J. H. Marco Jansen, Peter Boross, PhD, Marije B. Overdijk, PhD student, Jeroen J. Lammerts van Bueren, PhD, Paul W.H.I. Parren, PhD, Jeanette H. W. Leusen, PhD
Journal: Blood
Blood (2012) 120 (21): 2974.
https://doi.org/10.1182/blood.V120.21.2974.2974
Published: 2012
Journal Articles

Phagocytosis Is A Mechanism of Action for Daratumumab

Marije B. Overdijk, PhD student, Sandra Verploegen, PhD, Bögels Marijn, PhD student, Marjolein van Egmond, Prof., Richard W.J. Groen, PhD, Anton C.M. Martens, PhD, Jeroen Lammerts van Bueren, PhD, Wim Bleeker, PhD, Paul W.H.I. Parren, PhD
Journal: Blood
Blood (2012) 120 (21): 4054.
https://doi.org/10.1182/blood.V120.21.4054.4054
Published: 2012