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Journal Articles

The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia

Blood (2019) 134 (Supplement_1): 847.

https://doi.org/10.1182/blood-2019-130052

Published: 2019

Journal Articles

Transcriptome and Somatic Mutation Associated with Non-Malignant Human T Lymphotropic Virus Type 1 Infection and Adult T-Cell Leukemia/Lymphoma

Huseini Hatimbhai Kagdi, MD PhD MBBS, FRCPath, MRCP, Graham Phillip Taylor, MB ChB, DSc, FRCP, FHEA

Blood (2018) 132 (Supplement 1): 2843.

https://doi.org/10.1182/blood-2018-99-111167

Published: 2018

Journal Articles

Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis

Blood (2017) 130 (Supplement 1): 473.

https://doi.org/10.1182/blood.V130.Suppl_1.473.473

Published: 2017

Journal Articles

An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition

Kamaleldin E Elagib, MBBS, PhD, Chih-Huan Lu, BS, Goar Mosoyan, Ewelina Zasadzińska, MS, Daniel R Foltz, PhD, Peter Balogh, Els Verhoeyen, Miriam Sansó, PhD, Robert P Fisher, MD PhD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2016) 128 (22): 886.

https://doi.org/10.1182/blood.V128.22.886.886

Published: 2016

Journal Articles

The Abnormal Repression of Mir-375 Expression By Overlapping Epigenetic Dysregulations in Myelomas

Shotaro Tatekawa, MD, Yoshiaki Chinen, MD PhD, Yuji Shimura, MD PhD, Yayoi Matsumura-Kimoto, MD, Hisao Nagoshi, MD PhD, Tsutomu Kobayashi, MD PhD, Eri Kawata, MD PhD, Tomoko Narita, MD PhD, Masaki Ri, MD PhD, Hiroshi Handa, MD PhD, Nobuhiko Uoshima, MD PhD, Shinsuke Iida, MD PhD, Junya Kuroda, MD PhD

Blood (2016) 128 (22): 4460.

https://doi.org/10.1182/blood.V128.22.4460.4460

Published: 2016

Journal Articles

SHQ1 Regulates MYC mRNA Splicing and Promotes T Cell Leukemogenesis

Hexiu Su, Yufeng Hu, Jue Jiang, Zhichao Chen, Hudan Liu

Blood (2016) 128 (22): 440.

https://doi.org/10.1182/blood.V128.22.440.440

Published: 2016

Journal Articles

Intron retention resulting from a silent mutation in the VWF gene that structurally influences the 5′ splice site

Hamideh Yadegari, Arijit Biswas, Mohammad Suhail Akhter, Julia Driesen, Vytautas Ivaskevicius, Natascha Marquardt, Johannes Oldenburg

Blood (2016) 128 (17): 2144–2152.

https://doi.org/10.1182/blood-2016-02-699686

Published: 2016

Includes: Supplemental data

Journal Articles

miRNA-146a, miRNA-203a, and miRNA-223 Modulate Inflammatory Response in LPS- Acute Lung Injury in Sickle Cell Transgenic Mice

Roger Barbosa Ferreira, Regiane Ferreira, MSc, BSc, Dulcineia Martins Albuquerque, PhD, Fernando F Costa, PhD MD, Carla Fernanda Franco-Penteado, BSc, PhD

Blood (2015) 126 (23): 3390.

https://doi.org/10.1182/blood.V126.23.3390.3390

Published: 2015

Journal Articles

The Epigenetic Repression of Mir-375 Is the Dominant Mechanism for the Constitutive Activation of PDPK1/RSK2 Signaling Axis in Multiple Myeloma

Shotaro Tatekawa, MD, Junya Kuroda, MD PhD, Yoshiaki Chinen, MD, Yuji Shimura, MD, Hisao Nagoshi, MD, Tsutomu Kobayashi, MD PhD, Eri Kawata, MD PhD, Nobuhiko Uoshima, MD PhD, Hiroshi Handa, MD PhD, Masafumi Taniwaki

Blood (2015) 126 (23): 4182.

https://doi.org/10.1182/blood.V126.23.4182.4182

Published: 2015

Journal Articles

The Distinctive Morphogenesis of Infantile Megakaryopoiesis Is Associated with Altered P-TEFb Regulation By the Oncofetal Factor IGF2BP3

Kamaleldin E Elagib, MBBS, PhD, Chih-Huan Lu, Ewelina Zasadzińska, MSc, Daniel R Foltz, PhD, Peter Balogh, MSc, Adam N Goldfarb, MD

Blood (2014) 124 (21): 2911.

https://doi.org/10.1182/blood.V124.21.2911.2911

Published: 2014

Journal Articles

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Francesca Nuzzo, Claudia Radu, Marco Baralle, Luca Spiezia, Tilman M. Hackeng, Paolo Simioni, Elisabetta Castoldi

Blood (2013) 122 (23): 3825–3831.

https://doi.org/10.1182/blood-2013-04-499657

Published: 2013

Includes: Supplemental data

Journal Articles

Characterization Of Oncogenes On Chromosome 21 Identified By shRNA-Based Viability Screening

Lena Stachorski, Veera Raghavan Thangapandi, Dirk Reinhardt, Jan-Henning Klusmann

Blood (2013) 122 (21): 1201.

https://doi.org/10.1182/blood.V122.21.1201.1201

Published: 2013

Journal Articles

Aberrant 3′ oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia

Christine Hilcenko, Paul J. Simpson, Andrew J. Finch, Frank R. Bowler, Mark J. Churcher, Li Jin, Len C. Packman, Adam Shlien, Peter Campbell, Michael Kirwan, Inderjeet Dokal, Alan J. Warren

Blood (2013) 121 (6): 1028–1038.

https://doi.org/10.1182/blood-2012-10-461491

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of Reference Genes for miRNA Profiling in Hematopoietic Cell Lineages

Shaji Abraham, Ph.D., Raul Teruel Montoya, Ph.D., Leonard C. Edelstein, PhD, Steven E. McKenzie, MD, PhD, Paul F. Bray, MD

Blood (2012) 120 (21): 3330.

https://doi.org/10.1182/blood.V120.21.3330.3330

Published: 2012

Journal Articles

Beyond mRNAs and Mirnas: Unraveling the Full-Spectrum of the Normal Human Platelet Transcriptome Through Next-Generation Sequencing

Eric R. Londin, PhD, Eleftheria Hatzimichael, MD, PhD, Phillipe Loher, BS, Yue Zhao, PhD, Yi Jing, MD, PhD, Huang Chen, PhD, Leonard C. Edelstein, PhD, Srikanth Nagalla, MD, MS, Kathleen Delgrosso, MS, Adam Ertel, PhD, Joan Kupper, BS, Paolo M. Fortina, MD, PhD, Steven E. McKenzie, MD, PhD, Paul F. Bray, MD, Isidore Rigoutsos, PhD

Blood (2012) 120 (21): 3298.

https://doi.org/10.1182/blood.V120.21.3298.3298

Published: 2012

Journal Articles

Delivery of a Modified U1 Small Nuclear RNA Alleviates Splicing-Defective Coagulation Factor VII Expression in Mouse Models

Dario Balestra, PhD, Armida Faella, Nicola Cavallari, PhD, Paris Margaritis, PhD, Franco Pagani, MD, Francesco Bernardi, PhD, Valder R Arruda, MD, PhD, Mirko Pinotti, PhD

Blood (2012) 120 (21): 754.

https://doi.org/10.1182/blood.V120.21.754.754

Published: 2012

Journal Articles

Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia

Kamaleldin Elagib, PhD, Jeremy D. Rubinstein, Lorrie L. Delehanty, Peter A. Greer, PhD, Shuran Li, Jae K. Lee, PhD, Ivailo S. Mihaylov, PhD, Zhe Li, PhD, Stuart H. Orkin, MD, Adam Goldfarb, MD

Blood (2011) 118 (21): 552.

https://doi.org/10.1182/blood.V118.21.552.552

Published: 2011

Journal Articles

Levels of Mir-29b or Mir-101 Do Not Predict Response In Patients (pts) with Acute Myelogenous Leukemia (AML) Treated with the Combination of 5-Azacytidine, Valproic Acid and ATRA

Hui Yang, MD, PhD, Zhihong Fang, Yue Wei, PhD, Yumin Hu, George Calin, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD

Blood (2010) 116 (21): 1701.

https://doi.org/10.1182/blood.V116.21.1701.1701

Published: 2010

Journal Articles

Calpain Regulation of Megakaryopoiesis through a Positive Regulatory Loop Involving P-TEFb, GATA-1, and RUNX1.

Kamaleldin E Elagib, Lorrie L Delehanty, Ivailo Mihaylov, Adam Goldfarb

Blood (2009) 114 (22): 566.

https://doi.org/10.1182/blood.V114.22.566.566

Published: 2009

Journal Articles

Fox-2A Modulates Protein 4.1R Exon 16 5' Splice Site Activation.

Shu-Ching Huang, Guang Yang, PhD, Jennie Park, Alexander Ou, Edward J. Benz, Jr., MD

Blood (2009) 114 (22): 778.

https://doi.org/10.1182/blood.V114.22.778.778

Published: 2009

NARROW

The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia

Transcriptome and Somatic Mutation Associated with Non-Malignant Human T Lymphotropic Virus Type 1 Infection and Adult T-Cell Leukemia/Lymphoma

Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis

An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition

The Abnormal Repression of Mir-375 Expression By Overlapping Epigenetic Dysregulations in Myelomas

SHQ1 Regulates MYC mRNA Splicing and Promotes T Cell Leukemogenesis

Intron retention resulting from a silent mutation in the VWF gene that structurally influences the 5′ splice site

miRNA-146a, miRNA-203a, and miRNA-223 Modulate Inflammatory Response in LPS- Acute Lung Injury in Sickle Cell Transgenic Mice

The Epigenetic Repression of Mir-375 Is the Dominant Mechanism for the Constitutive Activation of PDPK1/RSK2 Signaling Axis in Multiple Myeloma

The Distinctive Morphogenesis of Infantile Megakaryopoiesis Is Associated with Altered P-TEFb Regulation By the Oncofetal Factor IGF2BP3

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Characterization Of Oncogenes On Chromosome 21 Identified By shRNA-Based Viability Screening

Aberrant 3′ oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia

Identification of Reference Genes for miRNA Profiling in Hematopoietic Cell Lineages

Beyond mRNAs and Mirnas: Unraveling the Full-Spectrum of the Normal Human Platelet Transcriptome Through Next-Generation Sequencing

Delivery of a Modified U1 Small Nuclear RNA Alleviates Splicing-Defective Coagulation Factor VII Expression in Mouse Models

Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia

Levels of Mir-29b or Mir-101 Do Not Predict Response In Patients (pts) with Acute Myelogenous Leukemia (AML) Treated with the Combination of 5-Azacytidine, Valproic Acid and ATRA

Calpain Regulation of Megakaryopoiesis through a Positive Regulatory Loop Involving P-TEFb, GATA-1, and RUNX1.

Fox-2A Modulates Protein 4.1R Exon 16 5' Splice Site Activation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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