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Journal Articles

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII

Oscar A. Marcos-Contreras, Shannon M. Smith, Dwight A. Bellinger, Robin A. Raymer, Elizabeth Merricks, Armida Faella, Giulia Pavani, Shangzhen Zhou, Timothy C. Nichols, Katherine A. High, Paris Margaritis
Journal: Blood
Blood (2016) 127 (5): 565–571.
https://doi.org/10.1182/blood-2015-09-671420
Published: 2016
Includes: Supplemental data
Journal Articles

VKORc1 Is Under-Expressed in Skeletal Muscle of Humans, Dogs and Mice: Potential Implications for Ectopic Coagulation Factor Expression in Pre-Clinical and Therapeutic Applications

Courtney T Connolly, Armida Faella, Timothy C. Nichols, MD, Katherine A. High, MD, Valder R. Arruda, MD, PhD, Paris Margaritis, DPhil
Journal: Blood
Blood (2014) 124 (21): 1477.
https://doi.org/10.1182/blood.V124.21.1477.1477
Published: 2014
Journal Articles

The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo

Giulia Pavani, Lacramioara Ivanciu, Armida Faella, Oscar A. Marcos-Contreras, Paris Margaritis
Journal: Blood
Blood (2014) 124 (7): 1157–1165.
https://doi.org/10.1182/blood-2014-04-567297
Published: 2014
Includes: Supplemental data
Journal Articles

Insights Into the Mechanism of Zymogen Protein C Protection Against Cancer Progression

Julie M Crudele, BA, Geerte L. Van Sluis, MD, Paris Margaritis, DPhil, Joshua I Siner, Michael Sliozberg, Jenna Maurer, Armida Faella, Shangzhen Zhou, MD, Katherine A. High, MD, Charles T Esmon, PhD, C. Arnold Spek, PhD, Valder R Arruda, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3350.
https://doi.org/10.1182/blood.V120.21.3350.3350
Published: 2012
Journal Articles

A Novel Strategy to Circumvent Pre-Existing Humoral Immunity to AAV

Federico Mingozzi, PhD, Xavier M Anguela, PhD, Giulia Pavani, MS, Yifeng Chen, MD, Robert J Davidson, Daniel J. Hui, Ph.D., Christian J Hinderer, MS, Armida Faella, Crolann Howard, BS, Alex Tai, MS, Gregory M Podsakoff, Margaret V. Ragni, MD, MPH, Shangzhen Zhou, MD, Etiena Basner-Tschakarjan, J. Fraser Wright, PhD, Katherine A. High, MD
Journal: Blood
Blood (2012) 120 (21): 2050.
https://doi.org/10.1182/blood.V120.21.2050.2050
Published: 2012
Journal Articles

Delivery of a Modified U1 Small Nuclear RNA Alleviates Splicing-Defective Coagulation Factor VII Expression in Mouse Models

Dario Balestra, PhD, Armida Faella, Nicola Cavallari, PhD, Paris Margaritis, PhD, Franco Pagani, MD, Francesco Bernardi, PhD, Valder R Arruda, MD, PhD, Mirko Pinotti, PhD
Journal: Blood
Blood (2012) 120 (21): 754.
https://doi.org/10.1182/blood.V120.21.754.754
Published: 2012
Journal Articles

Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo

Paris Margaritis, Elise Roy, Armida Faella, Harre D. Downey, Lacramioara Ivanciu, Giulia Pavani, Shangzhen Zhou, Ralph M. Bunte, Katherine A. High
Journal: Blood
Blood (2011) 117 (15): 3974–3982.
https://doi.org/10.1182/blood-2010-09-309732
Published: 2011
Includes: Supplemental data
Journal Articles

Zymogen Protein C as a Novel Modulator of Cancer Progression In Murine Models

Geerte L. Van Sluis, Paris Margaritis, DPhil, Michael Sliozberg, Jenna Mauer, Armida Faella, Shangzhen Zhou, Katherine A. High, MD, Arnold Spek, Valder R. Arruda, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 718.
https://doi.org/10.1182/blood.V116.21.718.718
Published: 2010
Journal Articles

Efficacy and Safety of Continuous Expression of An Improved Variant of FVIIa On Murine Hemostasis with or without Inhibitors to Human Factor IX.

Elise Roy, Armida Faella, Harre Downey, Lacramioara Ivanciu, Ph.D., Shangzhen Zhou, Katherine A. High, MD, Paris Margaritis, D.Phil
Journal: Blood
Blood (2009) 114 (22): 2466.
https://doi.org/10.1182/blood.V114.22.2466.2466
Published: 2009