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Elise Roy
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Journal Articles

Catalytic domain modification and viral gene delivery of activated factor VII confers hemostasis at reduced expression levels and vector doses in vivo

Paris Margaritis, Elise Roy, Armida Faella, Harre D. Downey, Lacramioara Ivanciu, Giulia Pavani, Shangzhen Zhou, Ralph M. Bunte, Katherine A. High
Journal: Blood
Blood (2011) 117 (15): 3974–3982.
https://doi.org/10.1182/blood-2010-09-309732
Published: 2011
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Continuous Expression of An Improved Variant of FVIIa On Murine Hemostasis with or without Inhibitors to Human Factor IX.

Elise Roy, Armida Faella, Harre Downey, Lacramioara Ivanciu, Ph.D., Shangzhen Zhou, Katherine A. High, MD, Paris Margaritis, D.Phil
Journal: Blood
Blood (2009) 114 (22): 2466.
https://doi.org/10.1182/blood.V114.22.2466.2466
Published: 2009
Journal Articles

Successful treatment of canine hemophilia by continuous expression of canine FVIIa

Paris Margaritis, Elise Roy, Majed N. Aljamali, Harre D. Downey, Urs Giger, Shangzhen Zhou, Elizabeth Merricks, Aaron Dillow, Mirella Ezban, Timothy C. Nichols, Katherine A. High
Journal: Blood
Blood (2009) 113 (16): 3682–3689.
https://doi.org/10.1182/blood-2008-07-168377
Published: 2009
Journal Articles

Successful and Safe Treatment of Canine Hemophilia by Continuous Expression of Canine FVIIa: a Model for FVIII/FIX Gene-Based Bypassing Agents

Paris Margaritis, Elise Roy, Majed N Aljamali, Harre Downey, Shangzhen Zhou, Elizabeth Merricks, Aaron Dillow, Timothy C Nichols, Katherine A. High, MD
Journal: Blood
Blood (2008) 112 (11): lba-4.
https://doi.org/10.1182/blood.V112.11.lba-4.lba-4
Published: 2008
Journal Articles

In Vitro and In Vivo Characterization of a Murine Model of Suppressed Intrinsic Pathway Using a FX Variant: FX Roma .

Elise Roy, MS, Paris Margaritis, PhD, Harre D. Downey, BS, Katherine A. High, MD
Journal: Blood
Blood (2007) 110 (11): 2697.
https://doi.org/10.1182/blood.V110.11.2697.2697
Published: 2007
Journal Articles

Gene Transfer of Canine FVIIa Results in Partial Correction of Canine Hemophilia: A Model for FVIII/FIX Gene-Based Bypassing Agents.

Paris Margaritis, PhD, Elise Roy, MS, Harre D. Downey, BS, Shangzen Zhou, PhD, Elizabeth Merricks, Aaron Dillow, Timothy C. Nichols, MD, Katherine A. High, MD
Journal: Blood
Blood (2007) 110 (11): 195.
https://doi.org/10.1182/blood.V110.11.195.195
Published: 2007
Journal Articles

A Murine FVIIa Variant with Increased Tissue Factor-Independent Intrinsic Activity Corrects the Murine Hemophilia B Phenotype Following AAV Administration: Implications for Therapeutic AAV Vector Doses.

Paris Margaritis, PhD, Elise Roy, MS, Katherine A. High, MD
Journal: Blood
Blood (2006) 108 (11): 3276.
https://doi.org/10.1182/blood.V108.11.3276.3276
Published: 2006