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Journal Articles

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells

Geoffrey L. Rogers, Jamie L. Shirley, Irene Zolotukhin, Sandeep R. P. Kumar, Alexandra Sherman, George Q. Perrin, Brad E. Hoffman, Arun Srivastava, Etiena Basner-Tschakarjan, Mark A. Wallet, Cox Terhorst, Moanaro Biswas, Roland W. Herzog

Blood (2017) 129 (24): 3184–3195.

https://doi.org/10.1182/blood-2016-11-751040

Published: 2017

Includes: Supplemental data

Journal Articles

Cellular Immune Responses To Vector In a Gene Therapy Trial For Hemophilia B Using An AAV8 Self-Complementary Factor IX Vector

Etiena Basner-Tschakarjan, MD PhD, Federico Mingozzi, PhD, Yifeng Chen, MD, Amit Nathwani, MD, PhD, Edward Tuddenham, MD, Anne Riddell, BSc, Catherine Ng, MS, Pradip Rustagi, MD, Bertil Glader, MD, PhD, Mark Kay, MD, PhD, Ulrike M. Reiss, MD, Arthur W. Nienhuis, MD, Andrew Davidoff, MD, Katherine A. High, MD

Blood (2013) 122 (21): 717.

https://doi.org/10.1182/blood.V122.21.717.717

Published: 2013

Journal Articles

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8 + T cells

Ashley T. Martino, Etiena Basner-Tschakarjan, David M. Markusic, Jonathan D. Finn, Christian Hinderer, Shangzhen Zhou, David A. Ostrov, Arun Srivastava, Hildegund C. J. Ertl, Cox Terhorst, Katherine A. High, Federico Mingozzi, Roland W. Herzog

Blood (2013) 121 (12): 2224–2233.

https://doi.org/10.1182/blood-2012-10-460733

Published: 2013

Includes: Supplemental data

Journal Articles

A Novel Strategy to Circumvent Pre-Existing Humoral Immunity to AAV

Federico Mingozzi, PhD, Xavier M Anguela, PhD, Giulia Pavani, MS, Yifeng Chen, MD, Robert J Davidson, Daniel J. Hui, Ph.D., Christian J Hinderer, MS, Armida Faella, Crolann Howard, BS, Alex Tai, MS, Gregory M Podsakoff, Margaret V. Ragni, MD, MPH, Shangzhen Zhou, MD, Etiena Basner-Tschakarjan, J. Fraser Wright, PhD, Katherine A. High, MD

Blood (2012) 120 (21): 2050.

https://doi.org/10.1182/blood.V120.21.2050.2050

Published: 2012

Journal Articles

Stable Factor IX Activity Following AAV-Mediated Gene Transfer in Patients with Severe Hemophilia B

Blood (2012) 120 (21): 752.

https://doi.org/10.1182/blood.V120.21.752.752

Published: 2012

Journal Articles

Adeno-Associated Viral Vector Mediated Gene Transfer for Hemophilia B

Blood (2011) 118 (21): 5.

https://doi.org/10.1182/blood.V118.21.5.5

Published: 2011

Journal Articles

Peptide-Induced Antigen-Specific CD4 + CD25 + FoxP3 + T Cells Suppress Cytotoxicity T Cell Responses Directed Against the AAV Capsid.

Daniel J. Hui, PhD, Etiena Basner-Tschakarjan, MD, Gary C. Pien, MD, PhD, William D. Martin, Annie S. DeGroot, MD, Katherine A. High, MD, Federico Mingozzi, PhD

Blood (2010) 116 (21): 3769.

https://doi.org/10.1182/blood.V116.21.3769.3769

Published: 2010

Journal Articles

Suppression of CTL Responses against AAV-Capsid Epitopes by Peptide-Induced Regulatory T Cells.

Daniel J Hui, Ph.D., Gary C Pien, MD, PhD, Etiena Basner-Tschakarjan, M.D., Federico Mingozzi, PhD, Jonathan D Finn, PhD, Shangzhen Zhou, Ph.D., William Martin, Anne S. De Groot, M.D., Katherine A. High, MD

Blood (2009) 114 (22): 377.

https://doi.org/10.1182/blood.V114.22.377.377

Published: 2009

Journal Articles

AAV-1–mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

Federico Mingozzi, Janneke J. Meulenberg, Daniel J. Hui, Etiena Basner-Tschakarjan, Nicole C. Hasbrouck, Shyrie A. Edmonson, Natalie A. Hutnick, Michael R. Betts, John J. Kastelein, Erik S. Stroes, Katherine A. High

Blood (2009) 114 (10): 2077–2086.

https://doi.org/10.1182/blood-2008-07-167510

Published: 2009

Includes: Supplemental data

Journal Articles

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver

Federico Mingozzi, Nicole C. Hasbrouck, Etiena Basner-Tschakarjan, Shyrie A. Edmonson, Daniel J. Hui, Denise E. Sabatino, Shangzhen Zhou, J. Fraser Wright, Haiyan Jiang, Glenn F. Pierce, Valder R. Arruda, Katherine A. High

Blood (2007) 110 (7): 2334–2341.

https://doi.org/10.1182/blood-2007-03-080093

Published: 2007

NARROW

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells

Cellular Immune Responses To Vector In a Gene Therapy Trial For Hemophilia B Using An AAV8 Self-Complementary Factor IX Vector

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8 + T cells

A Novel Strategy to Circumvent Pre-Existing Humoral Immunity to AAV

Stable Factor IX Activity Following AAV-Mediated Gene Transfer in Patients with Severe Hemophilia B

Adeno-Associated Viral Vector Mediated Gene Transfer for Hemophilia B

Peptide-Induced Antigen-Specific CD4 + CD25 + FoxP3 + T Cells Suppress Cytotoxicity T Cell Responses Directed Against the AAV Capsid.

Suppression of CTL Responses against AAV-Capsid Epitopes by Peptide-Induced Regulatory T Cells.

AAV-1–mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver

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American Society of Hematology

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ASH Publications

American Society of Hematology

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