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Journal Articles

Factor VIII trafficking to CD4 + T cells shapes its immunogenicity and requires several types of antigen-presenting cells

Radoslaw Kaczmarek, Annie R. Piñeros, Paige E. Patterson, Thais B. Bertolini, George Q. Perrin, Alexandra Sherman, Jameson Born, Sreevani Arisa, Matthew C. Arvin, Malgorzata M. Kamocka, Michelle M. Martinez, Kenneth W. Dunn, Sean M. Quinn, Johnathan J. Morris, Amelia R. Wilhelm, Tsuneyasu Kaisho, Maite Munoz-Melero, Moanaro Biswas, Mark H. Kaplan, Amelia K. Linnemann, Lindsey A. George, Rodney M. Camire, Roland W. Herzog
Journal: Blood
Blood (2023) 142 (3): 290–305.
https://doi.org/10.1182/blood.2022018937
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Factor IX Delivery to the Skin Primes Inhibitor Formation and Sensitizes Hemophilia B Mice to Systemic Factor IX Administration

Radoslaw Kaczmarek, Thais Bertolini, Roland W Herzog, Alexandra Sherman
Journal: Blood
Blood (2021) 138 (Supplement 1): 3194.
https://doi.org/10.1182/blood-2021-154146
Published: 2021
Journal Articles

Toll-like Receptor 9 Activation Accelerates Inhibitor Formation in Response to Factor VIII

Radoslaw Kaczmarek, Alexandra Sherman, DVM, Moanaro Biswas, PhD, Roland W Herzog, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1113.
https://doi.org/10.1182/blood-2019-125348
Published: 2019
Journal Articles

Innate Immune Activation Via TLR9 May Enhance Antibody Formation Against Factors VIII and IX in Protein and Gene Therapy

Roland W Herzog, PhD, Alexandra Sherman, DVM, Brad E. Hoffman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3651.
https://doi.org/10.1182/blood.V130.Suppl_1.3651.3651
Published: 2017
Journal Articles

Lettuce Plants Expressing High Levels of Factor VIII Antigen in the Chloroplast for Oral Tolerance in Hemophilia a

Roland W Herzog, PhD, Alexandra Sherman, DVM, Kwang-Chul Kwon, PhD, Wan-Jung Chang, MS, Henry Daniell, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 362.
https://doi.org/10.1182/blood.V130.Suppl_1.362.362
Published: 2017
Journal Articles

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8 + T cells

Geoffrey L. Rogers, Jamie L. Shirley, Irene Zolotukhin, Sandeep R. P. Kumar, Alexandra Sherman, George Q. Perrin, Brad E. Hoffman, Arun Srivastava, Etiena Basner-Tschakarjan, Mark A. Wallet, Cox Terhorst, Moanaro Biswas, Roland W. Herzog
Journal: Blood
Blood (2017) 129 (24): 3184–3195.
https://doi.org/10.1182/blood-2016-11-751040
Published: 2017
Includes: Supplemental data
Journal Articles

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP + CD4 + T cells

Xiaomei Wang, Jin Su, Alexandra Sherman, Geoffrey L. Rogers, Gongxian Liao, Brad E. Hoffman, Kam W. Leong, Cox Terhorst, Henry Daniell, Roland W. Herzog
Journal: Blood
Blood (2015) 125 (15): 2418–2427.
https://doi.org/10.1182/blood-2014-08-597070
Published: 2015
Includes: Supplemental data
Journal Articles

Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells

Alexandra Sherman, Jin Su, Shina Lin, Xiaomei Wang, Roland W. Herzog, Henry Daniell
Journal: Blood
Blood (2014) 124 (10): 1659–1668.
https://doi.org/10.1182/blood-2013-10-528737
Published: 2014
Includes: Supplemental data
Journal Articles

Mechanism Of Oral Tolerance Induced By Bioencapsulated Coagulation Factor IX In Hemophilia B Mice

Xiaomei Wang, PhD, Alexandra Sherman, DVM, Jin Su, PhD, Henry Daniell, PhD, Roland W Herzog, PhD
Journal: Blood
Blood (2013) 122 (21): 30.
https://doi.org/10.1182/blood.V122.21.30.30
Published: 2013
Journal Articles

Suppression of Inhibitor Formation Against Factor VIII in Hemophilia A Mice by Oral Delivery of Bioencapsulated Antigen

Roland W Herzog, PhD, Dheeraj Verma, PhD, Xiaomei Wang, PhD, Alexandra Sherman, DVM, Shina Lin, BS, Henry Daniell, PhD
Journal: Blood
Blood (2012) 120 (21): 14.
https://doi.org/10.1182/blood.V120.21.14.14
Published: 2012