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Journal Articles

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII

Oscar A. Marcos-Contreras, Shannon M. Smith, Dwight A. Bellinger, Robin A. Raymer, Elizabeth Merricks, Armida Faella, Giulia Pavani, Shangzhen Zhou, Timothy C. Nichols, Katherine A. High, Paris Margaritis

Blood (2016) 127 (5): 565–571.

https://doi.org/10.1182/blood-2015-09-671420

Published: 2016

Includes: Supplemental data

Journal Articles

A Novel Canine Model of Immune Thrombocytopenia

Dana N LeVine, DVM, DACVIM, Adam J Birkenheuer, DVM, PhD, DACVIM, Marjory B Brooks, DVM, DACVIM, Shila K Nordone, PhD, Dwight A Bellinger, DVM, PhD, Sam L Jones, DVM, PhD, DACVIM, Thomas H Fischer, PhD, D A Esserman, PhD, Stephen E Oglesbee, PhD, Nigel S Key, MBChB

Blood (2012) 120 (21): 3326.

https://doi.org/10.1182/blood.V120.21.3326.3326

Published: 2012

Journal Articles

Dynamic Changes in Platelet Responsiveness to Thrombin and Coated Platelet Potential May Inform Risk of Hemorrhage and/or Thrombosis in a Novel Canine Mode of Immune Thrombocytopenia.

Marshall A. Mazepa, MD, Dana N LeVine, DVM, DACVIM, Adam J Birkenheuer, DVM, PhD, DACVIM, Marjory B Brooks, DVM, DACVIM, Shila K Nordone, PhD, Dwight A Bellinger, DVM, PhD, Sam L Jones, DVM, PhD, DACVIM, Thomas H Fischer, PhD, Jonathan E Fogle, DVM PhD DACVIM, Nigel S Key, MBChB

Blood (2012) 120 (21): 2193.

https://doi.org/10.1182/blood.V120.21.2193.2193

Published: 2012

Journal Articles

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B

Valder R. Arruda, Hansell H. Stedman, Virginia Haurigot, George Buchlis, Stefano Baila, Patricia Favaro, Yifeng Chen, Helen G. Franck, Shangzhen Zhou, J. Fraser Wright, Linda B. Couto, Haiyan Jiang, Glenn F. Pierce, Dwight A. Bellinger, Federico Mingozzi, Timothy C. Nichols, Katherine A. High

Blood (2010) 115 (23): 4678–4688.

https://doi.org/10.1182/blood-2009-12-261156

Published: 2010

Journal Articles

Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy

Lili Wang, Roberto Calcedo, Timothy C. Nichols, Dwight A. Bellinger, Aaron Dillow, Inder M. Verma, James M. Wilson

Blood (2005) 105 (8): 3079–3086.

https://doi.org/10.1182/blood-2004-10-3867

Published: 2005

Journal Articles

Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs

Karen E. Russell, Eva H. N. Olsen, Robin A. Raymer, Elizabeth P. Merricks, Dwight A. Bellinger, Marjorie S. Read, Bonita J. Rup, James C. Keith, Jr, Kyle P. McCarthy, Robert G. Schaub, Timothy C. Nichols

Blood (2003) 102 (13): 4393–4398.

https://doi.org/10.1182/blood-2003-05-1498

Published: 2003

Journal Articles

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia

Anja Ehrhardt, Hui Xu, Aaron M. Dillow, Dwight A. Bellinger, Timothy C. Nichols, Mark A. Kay

Blood (2003) 102 (7): 2403–2411.

https://doi.org/10.1182/blood-2003-01-0314

Published: 2003

Journal Articles

Comparative response of plasma VWF in dogs to up-regulation of VWF mRNA by interleukin-11 versus Weibel-Palade body release by desmopressin (DDAVP)

Eva H. N. Olsen, Arlene S. McCain, Elizabeth P. Merricks, Thomas H. Fischer, Ivy M. Dillon, Robin A. Raymer, Dwight A. Bellinger, Scot A. Fahs, Robert R. Montgomery, James C. Keith, Jr, Robert G. Schaub, Timothy C. Nichols

Blood (2003) 102 (2): 436–441.

https://doi.org/10.1182/blood-2003-01-0290

Published: 2003

Journal Articles

Neonatal or hepatocyte growth factor–potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B

Lingfei Xu, Cuihua Gao, Mark S. Sands, Shi-Rong Cai, Timothy C. Nichols, Dwight A. Bellinger, Robin A. Raymer, Stephanie McCorquodale, Katherine Parker Ponder

Blood (2003) 101 (10): 3924–3932.

https://doi.org/10.1182/blood-2002-10-3050

Published: 2003

NARROW

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII

A Novel Canine Model of Immune Thrombocytopenia

Dynamic Changes in Platelet Responsiveness to Thrombin and Coated Platelet Potential May Inform Risk of Hemorrhage and/or Thrombosis in a Novel Canine Mode of Immune Thrombocytopenia.

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B

Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy

Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia

Comparative response of plasma VWF in dogs to up-regulation of VWF mRNA by interleukin-11 versus Weibel-Palade body release by desmopressin (DDAVP)

Neonatal or hepatocyte growth factor–potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B

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American Society of Hematology

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American Society of Hematology

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