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Journal Articles

Targeting Homologous Recombination in Lymphoid Malignancies: Evaluation of Four Small Molecule Inhibitors of RAD51

Melinda Day, PhD, Tyler Maclay, Amber Cyr, Muneer G Hasham, PhD, Kin-hoe Chow, ED Keniston, Kevin Mills, PhD

Blood (2019) 134 (Supplement_1): 2080.

https://doi.org/10.1182/blood-2019-131747

Published: 2019

Journal Articles

Variability in Killler Immunglobulin like Receptor Gene Expression As a Periodic Function of Gene Position on Chromosome 19

Elizabeth Krieger, MD, Urmila Sivagnanaling, Katherine Webb, Rehan Qayyum, MD, Amir Ahmed Toor, MBBS

Blood (2019) 134 (Supplement_1): 3608.

https://doi.org/10.1182/blood-2019-132270

Published: 2019

Journal Articles

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Tamar Aprahamian, PhD, ED Keniston, Jane Branca, Muneer G Hasham, PhD, Melinda Day, PhD, Kevin Mills, PhD

Blood (2019) 134 (Supplement_1): 2330.

https://doi.org/10.1182/blood-2019-131311

Published: 2019

Journal Articles

Cells Deficient in the Shwachman-Diamond Syndrome Protein SBDS or the Diamond-Blackfan Anemia Protein RPS19 Have Impaired Homologous Recombination

Elif Asik, PhD, Nimrat Chatterjee, PhD, Alison A. Bertuch, MD PhD

Blood (2019) 134 (Supplement_1): 104.

https://doi.org/10.1182/blood-2019-128953

Published: 2019

Journal Articles

Genetic Vulnerabilities of DNMT3A R882H in Myeloid Malignancies

Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Konstantinos Tzelepis, Aristi Damaskou, MSc, Vijay Baskar, PhD, Penny Wright, Graham Duddy, Eshwar Meduri, PhD, Milena Mazan, PhD, Kosuke Yusa, PhD, Brian J. P. Huntly, PhD MRCP, MB, FRCPath, George S. Vassiliou, FRCPath, MRCP, PhD

Blood (2019) 134 (Supplement_1): 111.

https://doi.org/10.1182/blood-2019-126505

Published: 2019

Journal Articles

FT819: Translation of Off-the-Shelf TCR-Less Trac-1XX CAR-T Cells in Support of First-of-Kind Phase I Clinical Trial

Blood (2019) 134 (Supplement_1): 4434.

https://doi.org/10.1182/blood-2019-130584

Published: 2019

Journal Articles

DNA Methyltransferase Inhibitors Promote Homologous Recombination Deficiency through Induction of Immune Signaling, Sensitizing Acute Myeloid Leukemia Cells to PARP Inhibitors

Aksinija A Kogan, BS, MS, Lena J Mclaughlin, BS, Maria R. Baer, MD, Stephen Baylin, MD, Michael Topper, BS, Feyruz V. Rassool, BSc, PhD

Blood (2019) 134 (Supplement_1): 3763.

https://doi.org/10.1182/blood-2019-129535

Published: 2019

Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4385.

https://doi.org/10.1182/blood-2019-130700

Published: 2019

Journal Articles

Synthetic Lethal Interaction between Apto-253 and IDH1/2 Mutations

Cheng-Yu Tsai, PhD, Hongying Zhang, MD PhD, William G Rice, PhD, Stephen B Howell, MD

Blood (2019) 134 (Supplement_1): 5755.

https://doi.org/10.1182/blood-2019-123571

Published: 2019

Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 748.

https://doi.org/10.1182/blood-2019-127263

Published: 2019

Journal Articles

RAGs usurp cellular factors for both breaking and repairing

Katheryn Meek

Blood (2019) 133 (8): 773–774.

https://doi.org/10.1182/blood-2019-01-892729

Published: 2019

Journal Articles

A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination

Daniel T. Thwaites, Clive Carter, Dylan Lawless, Sinisa Savic, Joan M. Boyes

Blood (2019) 133 (8): 820–829.

https://doi.org/10.1182/blood-2018-07-866939

Published: 2019

Includes: Supplemental data

Journal Articles

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E. Desanti, Alexandra Mazharian, Yotis A. Senis

Blood (2019) 133 (4): 331–343.

https://doi.org/10.1182/blood-2018-09-877787

Published: 2019

Includes: Supplemental data

Journal Articles

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Keigo Akuta, Kazunobu Kiyomizu, MD, Hirokazu Kashiwagi, Shinji Kunishima, PhD, Fumiaki Banno, Koichi Kokame, Nobuko Nishiura, Hisashi Kato, MD PhD, Shigenori Honda, MD, Yuzuru Kanakura, MD PhD, Toshiyuki Miyata, Yoshiaki Tomiyama, MD

Blood (2018) 132 (Supplement 1): 3743.

https://doi.org/10.1182/blood-2018-99-115953

Published: 2018

Journal Articles

Single-Cell Characterization of the HSC-Supportive Bone Marrow Vascular Microenvironment

Michael Poulos, PhD, David Redmond, PhD, Michael Gutkin, MS, Pradeep Ramalingam, MD, Jason M. Butler, PhD

Blood (2018) 132 (Supplement 1): 2577.

https://doi.org/10.1182/blood-2018-99-120339

Published: 2018

Journal Articles

The Abnormal Expression and Mutation of Recombination Signal Binding Protein-Jk Gene Mightbe Contribute to the Proliferation of CD59 - Clone in Paroxysmal Nocturnal Hemoglobinuria Patients

Rong Fu, PhD, Liyan LI, Zhaoyun Liu, Hui Liu, Honglei Wang, Yingying Chen, Zonghong Shao, MD

Blood (2018) 132 (Supplement 1): 3618.

https://doi.org/10.1182/blood-2018-99-115887

Published: 2018

Journal Articles

The Complex Role of KDM6A in B-Cell Development and Function

Ling Tian, PhD, Monique Chavez, B.S., Lukas D Wartman, MD

Blood (2018) 132 (Supplement 1): 513.

https://doi.org/10.1182/blood-2018-99-119538

Published: 2018

Journal Articles

The Lysine Histone Methyltransferase SETD2 Is Required for Appropriate Immunoglobulin VDJ Recombination

S. Haihua Chu, PhD, Jonathan Chabon, BS, Janna Minehart, BS, Chloe N Matovina, BS, Jian Zhang, Bo-Ruei Chen, PhD, Elsa Callen-Moreu, PhD, Putzer J Hung, Zhaohui Feng, BM, BS, Richard Koche, PhD, X. Shirley Liu, Jayanta Chaudhuri, Andre Nussenzweig, PhD, Barry Sleckman, Scott A. Armstrong, MD PhD

Blood (2018) 132 (Supplement 1): 511.

https://doi.org/10.1182/blood-2018-99-111952

Published: 2018

Journal Articles

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Meiling May, BA, Stephen Desiderio, MD PhD, John Thomas Bettridge, BA

Blood (2018) 132 (Supplement 1): 512.

https://doi.org/10.1182/blood-2018-99-116675

Published: 2018

Journal Articles

Loss of Abelson Interactor-1 Is Linked to Inflammatory Hematopoiesis and Accelerated Aging of Hematopoietic System

Anna Dorota Chorzalska, PhD, John Morgan, PhD, Max Petersen, Diana O Treaba, MD, Adam J Olszewski, MD, John L. Reagan, MD, Patrycja Dubielecka, PhD

Blood (2018) 132 (Supplement 1): 1285.

https://doi.org/10.1182/blood-2018-99-118393

Published: 2018

NARROW

Targeting Homologous Recombination in Lymphoid Malignancies: Evaluation of Four Small Molecule Inhibitors of RAD51

Variability in Killler Immunglobulin like Receptor Gene Expression As a Periodic Function of Gene Position on Chromosome 19

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Cells Deficient in the Shwachman-Diamond Syndrome Protein SBDS or the Diamond-Blackfan Anemia Protein RPS19 Have Impaired Homologous Recombination

Genetic Vulnerabilities of DNMT3A R882H in Myeloid Malignancies

FT819: Translation of Off-the-Shelf TCR-Less Trac-1XX CAR-T Cells in Support of First-of-Kind Phase I Clinical Trial

DNA Methyltransferase Inhibitors Promote Homologous Recombination Deficiency through Induction of Immune Signaling, Sensitizing Acute Myeloid Leukemia Cells to PARP Inhibitors

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Synthetic Lethal Interaction between Apto-253 and IDH1/2 Mutations

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

RAGs usurp cellular factors for both breaking and repairing

A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

αIIb(R990W), a Gain-of Function Mutation of αIIbβ3, Knock-in Mice Show Moderately Impaired Thrombopoiesis

Single-Cell Characterization of the HSC-Supportive Bone Marrow Vascular Microenvironment

The Abnormal Expression and Mutation of Recombination Signal Binding Protein-Jk Gene Mightbe Contribute to the Proliferation of CD59 - Clone in Paroxysmal Nocturnal Hemoglobinuria Patients

The Complex Role of KDM6A in B-Cell Development and Function

The Lysine Histone Methyltransferase SETD2 Is Required for Appropriate Immunoglobulin VDJ Recombination

An Allosteric Mechanism for Epigenetic Activation of the V(D)J Recombinase

Loss of Abelson Interactor-1 Is Linked to Inflammatory Hematopoiesis and Accelerated Aging of Hematopoietic System

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American Society of Hematology

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ASH Publications

American Society of Hematology

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