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Journal Articles

Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Jenny Klintman, Niamh Appleby, Basile Stamatopoulos, Katie Ridout, Toby A. Eyre, Pauline Robbe, Laura Lopez Pascua, Samantha J. L. Knight, Helene Dreau, Maite Cabes, Niko Popitsch, Mats Ehinger, Jose I. Martín-Subero, Elías Campo, Robert Månsson, Davide Rossi, Jenny C. Taylor, Dimitrios V. Vavoulis, Anna Schuh

Blood (2021) 137 (20): 2800–2816.

https://doi.org/10.1182/blood.2020005650

Published: 2021

Includes: Supplemental data

Journal Articles

Extended Half-Life of the Double-Chain Recombinant Factor VIII-Fc Fusion Protein (FRSW107) in Hemophilia a Patients

Feng Xue, MD, Jing Sun, MD, Yun Chen, MD, Xinsheng Zhang, MD, Haiyan Sun, MD, Yali Wang, PhD, Renchi Yang, MD

Blood (2019) 134 (Supplement_1): 4932.

https://doi.org/10.1182/blood-2019-128600

Published: 2019

Journal Articles

Real-World Effectiveness and Safety of BAY 94-9027 (Damoctocog Alfa Pegol) in Previously Treated Patients with Hemophilia A (HEM-POWR): Online Patient Portal and LIFE-ACTIVE Sub-Study

Johannes Oldenburg, María Teresa Alvarez Román, Giancarlo Castaman, Maissaa Janbain, MD, Tadashi Matsushita, Karina Meijer, Sabine Friedl, Martin Sanabria, Mark Reding

Blood (2019) 134 (Supplement_1): 4943.

https://doi.org/10.1182/blood-2019-128140

Published: 2019

Journal Articles

RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms

Garima Pandey, Nathan Horvat, Narmin E. Amin, Afua A. Akuffo, Christelle Colin, Pearlie K. Epling-Burnette, Gary W. Reuther

Blood (2019) 134 (Supplement_1): 4198.

https://doi.org/10.1182/blood-2019-128937

Published: 2019

Journal Articles

Lack of Inhibitor Development in the American Thrombosis and Hemostasis Network (ATHN)-2 Factor Switching Study: Preliminary Report of Primary Outcome

Robert F. Sidonio, Jr., MD MSc, Dunlei Cheng, PhD, Christine Guelcher, PPCNP-BC, Janna M. Journeycake, MD, Susan U Lattimore, Clifford Takemoto, MD, Michael D. Tarantino, MD, Crystal Watson, Ellis J. Neufeld, MD, Carol Fedor, RN

Blood (2019) 134 (Supplement_1): 1114.

https://doi.org/10.1182/blood-2019-128612

Published: 2019

Journal Articles

Combination of the MEK Inhibitor Trametinib and Pyrvinium Pamoate Efficiently Targets RAS Pathway-Mutated Acute Myeloid Leukemia in Preclinical Models

Blood (2019) 134 (Supplement_1): 2671.

https://doi.org/10.1182/blood-2019-123418

Published: 2019

Journal Articles

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

Mario Angelo Pagano, Elena Tibaldi, Giulia Calabretto, Antonella Teramo, Luca Dell'Amico, Gabriella Donà, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Valentina Trimarco, Monica Facco, Francesco Piazza, Gianpietro Semenzato, Anna Maria Brunati, Renato Zambello

Blood (2019) 134 (Supplement_1): 2798.

https://doi.org/10.1182/blood-2019-129883

Published: 2019

Journal Articles

The Role of Protein Tyrosine Phosphatase PTP4A3 in T-Cell Acute Lymphoblastic Leukemia Progression

Min Wei, MSc, Jessica Blackburn, PhD

Blood (2019) 134 (Supplement_1): 2539.

https://doi.org/10.1182/blood-2019-126256

Published: 2019

Journal Articles

Inhibitor Development with Simoctocog Alfa in Previously Untreated Patients with Severe Haemophilia a: Final Results of the Nuprotect Study

Ri Liesner, Ellis J. Neufeld, MD

Blood (2019) 134 (Supplement_1): 903.

https://doi.org/10.1182/blood-2019-125520

Published: 2019

Journal Articles

PTPN11 Mutations Confer Unique Metabolic Properties and Increase Resistance to Venetoclax and Azacitidine in Acute Myelogenous Leukemia

Brett M. Stevens, PhDBS, Courtney L Jones, PhD, Amanda Winters, MDPhD, James Dugan, MD, Diana Abbott, PhD, Michael R. Savona, MD, Stephen W. Fesik, PhD, Daniel A Pollyea, MD, Craig T Jordan, PhD

Blood (2018) 132 (Supplement 1): 909.

https://doi.org/10.1182/blood-2018-99-119806

Published: 2018

Journal Articles

Clonal Evolution of a Mutation in PTPRA As a Potential Cause for Resistance Against Anti-CD19 Directed Chimeric Antigen Receptor T-Cell (CAR-T) Therapy with CTL019 in DLBCL Patients

Hyatt Balke-Want, MD, Philipp Gödel, MD, Nima Abedpour, PhD, Martin Peifer, PhD, Peter Borchmann, MD

Blood (2018) 132 (Supplement 1): 4119.

https://doi.org/10.1182/blood-2018-99-110600

Published: 2018

Journal Articles

Studying Methylation Status of Protein Tyrosine Phosphatase Receptor Gamma (PTPRG) in Chronic Myeloid Leukemia Patients in the State of Qatar

Mohamed Ismail, BS, MSc, Marzia Vezzalini, Ali Al Sayab, Maria Monne, Vinod Gupta, Govundarajulu Varadharaj, Mohamed Alsharshani, Mohamed Yassin, Claudio Sorio, MD PhD, Helmout Modjtahedi, Nader I. Al-Dewik, PhD

Blood (2018) 132 (Supplement 1): 5124.

https://doi.org/10.1182/blood-2018-99-113482

Published: 2018

Journal Articles

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Nikolaos Patsoukis, PhD, Jonathan Duke-Cohan, PhD, Apoorvi Chaudhri, Eunyoung Park, PhD, Council Asia, Anders Berg, MD PhD, Gordon J Freeman, PhD, Michael Eck, Vassiliki A Boussiotis, MD PhD

Blood (2018) 132 (Supplement 1): 862.

https://doi.org/10.1182/blood-2018-99-117486

Published: 2018

Journal Articles

Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML

Roshni Patel, BS, Baskar Ramdas, PhD, Lisa Deng, PhD, Victoria Jideonwo-Auman, PhD, Rebecca J Chan, MD PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 2623.

https://doi.org/10.1182/blood-2018-99-118802

Published: 2018

Journal Articles

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

Deepa Jayakody Arachchillage, MD MRCP, FRCPath, Sanjay Khanna, Christophe Vandenbriele, Jonthan Dutton, Alex Rosenberg, MRCP, FCICM, FFICM, TC Aw, FRCA, Winston Banya, Maurizio Passariello, EDIC, Michael Laffan, DM, FRCP, FRCPath, Stephane Ledot, EDIC, MD, Brijesh Patel, MRCP, FRCA, FFICM , PhD

Blood (2018) 132 (Supplement 1): 2451.

https://doi.org/10.1182/blood-2018-99-119143

Published: 2018

Journal Articles

Acute Myeloid Leukemia (AML) with Somatic Mutations in PTPN11 Is Associated with Treatment Resistance and Poor Overall Survival

Justin D. Kaner, MD, Nuria Mencia-Trinchant, PhD, Ariel Schaap, MD, Gail J. Roboz, MD, Sangmin Lee, MD, Pinkal Desai, MD MPH, Michael Samuel, MD, Spencer Krichevsky, BS, Idongessit Udoyen, Duane C. Hassane, PhD, Monica L. Guzman, PhD, Ellen K. Ritchie, MD

Blood (2018) 132 (Supplement 1): 2760.

https://doi.org/10.1182/blood-2018-99-110319

Published: 2018

Journal Articles

99.3% of Inhibitors in Severe Hemophilia a Develop before Exposure Day 75. Time to Change Definition of Previously Treated Patients; Data from 1038 Patients with Severe Hemophilia a of the Pednet Registry

Blood (2018) 132 (Supplement 1): 2472.

https://doi.org/10.1182/blood-2018-99-114518

Published: 2018

Journal Articles

The Persistent Survival of MPN Cells to JAK2 Inhibition Is Dependent on SHP2 Activity, Which May Provide a Therapeutic Target to Enhance Current Anti-MPN Therapies

Garima Pandey, Guolin Zhang, Narmin Amin, Lucia Mazzacurati, Eric B. Haura, Gary W. Reuther, PhD

Blood (2018) 132 (Supplement 1): 3064.

https://doi.org/10.1182/blood-2018-99-118641

Published: 2018

Journal Articles

Ras-Driven B-Cell Transformation Targets Developmental Rewiring of Cytokine to Pre-B Cell Receptor Signaling

Lai N Chan, Christian Hurtz, PhD, Huimin Geng, PhD, Franziska Auer, PhD, Zhengshan Chen, MDPhD, Gang Xiao, PhD, Jae-Woong Lee, PhD, Kadriye Nehir Cosgun, PhD, B Hilda Ye, PhD, Markus Muschen, MD

Blood (2018) 132 (Supplement 1): 1336.

https://doi.org/10.1182/blood-2018-99-115514

Published: 2018

Journal Articles

CRISPR-Cas9 Mediated CD45 Knockout Inactivates Src Family Kinases and Impairs Cell Migration in Multiple Myeloma

Wing Yu Man, BSc, Tiffany Khong, BSc, PhD, Andrew Spencer, MBBS, MD FRACP, FRCPA

Blood (2018) 132 (Supplement 1): 1907.

https://doi.org/10.1182/blood-2018-99-117532

Published: 2018

NARROW

Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Extended Half-Life of the Double-Chain Recombinant Factor VIII-Fc Fusion Protein (FRSW107) in Hemophilia a Patients

Real-World Effectiveness and Safety of BAY 94-9027 (Damoctocog Alfa Pegol) in Previously Treated Patients with Hemophilia A (HEM-POWR): Online Patient Portal and LIFE-ACTIVE Sub-Study

RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms

Lack of Inhibitor Development in the American Thrombosis and Hemostasis Network (ATHN)-2 Factor Switching Study: Preliminary Report of Primary Outcome

Combination of the MEK Inhibitor Trametinib and Pyrvinium Pamoate Efficiently Targets RAS Pathway-Mutated Acute Myeloid Leukemia in Preclinical Models

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

The Role of Protein Tyrosine Phosphatase PTP4A3 in T-Cell Acute Lymphoblastic Leukemia Progression

Inhibitor Development with Simoctocog Alfa in Previously Untreated Patients with Severe Haemophilia a: Final Results of the Nuprotect Study

PTPN11 Mutations Confer Unique Metabolic Properties and Increase Resistance to Venetoclax and Azacitidine in Acute Myelogenous Leukemia

Clonal Evolution of a Mutation in PTPRA As a Potential Cause for Resistance Against Anti-CD19 Directed Chimeric Antigen Receptor T-Cell (CAR-T) Therapy with CTL019 in DLBCL Patients

Studying Methylation Status of Protein Tyrosine Phosphatase Receptor Gamma (PTPRG) in Chronic Myeloid Leukemia Patients in the State of Qatar

The Two SH2 Domains of SHP-2 Bridge Two PD-1 Molecules Resulting in SHP-2 Activation and PD-1-Mediated Inhibition

Combined Pharmacological Inhibition of Bruton's Tyrosine Kinase (BTK) and Phosphoinositide 3-Kinase (PI3K) p110δ Rescues Monocytosis, Thrombocytopenia, and Splenomegaly in a Genetic Mouse Model for JMML

Incidence of Thrombocytopenia and Heparin Induced Thrombocytopenia in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO) Compared to Cardiopulmonary Bypass and the Limited Sensitivity of Pre-Test Probability Score

Acute Myeloid Leukemia (AML) with Somatic Mutations in PTPN11 Is Associated with Treatment Resistance and Poor Overall Survival

99.3% of Inhibitors in Severe Hemophilia a Develop before Exposure Day 75. Time to Change Definition of Previously Treated Patients; Data from 1038 Patients with Severe Hemophilia a of the Pednet Registry

The Persistent Survival of MPN Cells to JAK2 Inhibition Is Dependent on SHP2 Activity, Which May Provide a Therapeutic Target to Enhance Current Anti-MPN Therapies

Ras-Driven B-Cell Transformation Targets Developmental Rewiring of Cytokine to Pre-B Cell Receptor Signaling

CRISPR-Cas9 Mediated CD45 Knockout Inactivates Src Family Kinases and Impairs Cell Migration in Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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