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Journal Articles

A Genome-Wide CRISPR/Cas9 Knockout Screen Identifies BEND3 As a Determinant of Sensitivity to UBA1 Inhibition in Acute Myeloid Leukemia

Samir H Barghout, BSPharm, MSc, Neil MacLean, G. Wei Xu, Geethu Thomas, PhDMSc,BSc, Zachary Blatman, Rose Hurren, BSc, Aaron D Schimmer, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1350.
https://doi.org/10.1182/blood-2018-99-110406
Published: 2018
Journal Articles

Role of p38γ - NFATc4 - IL17A Pathway As a Potential Therapeutic Target in Cutaneous T Cell Lymphoma

Xu Hannah Zhang, PhD, Vu N. Ngo, PhD, Natalie Sandoval, MSc, Qi Cui, Yanhong Shi, PhD, Jasmine M. Zain, MD, Christiane Querfeld, MD PhD, Chao Guo, Xiwei Wu, PhD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 2725.
https://doi.org/10.1182/blood.V128.22.2725.2725
Published: 2016
Journal Articles

Targeting Deubiquitylating Enzyme USP1 in Multiple Myeloma

Deepika Sharma Das, PhD, Yan Song, PhD, Arghya Ray, PhD, Paul Richardson, MD, Dharminder Chauhan, PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2015) 126 (23): 1813.
https://doi.org/10.1182/blood.V126.23.1813.1813
Published: 2015
Journal Articles

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Nate Russell, Trevor Taylor, Kalindi Parmar, PhD, Alan D. D'Andrea, MD, Bradley B Brasher, Ph.D., Francesco D Melandri
Journal: Blood
Blood (2013) 122 (21): 4224.
https://doi.org/10.1182/blood.V122.21.4224.4224
Published: 2013
Journal Articles

Characterization Of In Vitro Hdm2 E3 Ubiquitin Ligase-Mediated p53 Ubiquitination

Bradley B Brasher, Ph.D., Eduardo Guillen, Ph.D., Ivan Tomasic, Carsten Schwerdtfeger, Ph.D., Francesco D Melandri
Journal: Blood
Blood (2013) 122 (21): 4903.
https://doi.org/10.1182/blood.V122.21.4903.4903
Published: 2013
Journal Articles

Molecular Defects In BRCC3 Complex, a Novel Pathogenic Pathway In MDS

Dayong Huang, MD, Hideki Makishima, MD, PhD, Yang Du, PhD, Naoko Hosono, MD, PhD, Wenyi Shen, MD, Chantana Polprasert, MD, Mikkael A. Sekeres, MD, MS, Bartlomiej Przychodzen, Ph.D., Richard A Padgett, PhD, Jarnail Singh, PhD, Kathryn M Guinta, Michael J. Clemente, Brittney Dienes, Manuel Afable, R.N., Holleh D Husseinzadeh, MD, Sarah Mcmahon, Yogen Saunthararajah, MD, Kenichi Yoshida, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Satoru Miyano, PhD, Seishi Ogawa, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP
Journal: Blood
Blood (2013) 122 (21): 264.
https://doi.org/10.1182/blood.V122.21.264.264
Published: 2013
Journal Articles

Deregulation of TLR2-JMJD3 Innate Immunity Signaling, Including a Rare TLR2 SNP As a Potential Somatic Mutation, in Myelodysplastic Syndromes (MDS)

Yue Wei, PhD, Rui Chen, Sophie Dimicoli, MD, PhD, Carlos E. Bueso-Ramos, MD, PhD, Donna S. Neuberg, ScD, Sherry A. Pierce, RN, BS, Hui Yang, MD, PhD., Yu Jia, Hong Zheng, Zhihong Fang, Martin Nguyen, Michael Fernandez, Sa A. Wang, MD, Hagop M. Kantarjian, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2012) 120 (21): 1700.
https://doi.org/10.1182/blood.V120.21.1700.1700
Published: 2012
Journal Articles

Degradation of TRAF6 by Bortezomib-Induced Autophagy Contributes to Cell Death in Acute Myeloid Leukemia and Myelodysplastic Syndrome

Jing Fang, MD/PhD, Lyndsey Bolanos, BSc, Garrett Rhyasen, BSc, Carmen Rigolino, BSc, Agostino Cortelezzi, MD, Esther Natalie Oliva, MD, Mariella Cuzzola, MD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2011) 118 (21): 2452.
https://doi.org/10.1182/blood.V118.21.2452.2452
Published: 2011
Journal Articles

New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein

Marjorie Hubeau, Flora Ngadjeua, Anne Puel, Laura Israel, Jacqueline Feinberg, Maya Chrabieh, Kiran Belani, Christine Bodemer, Isabelle Fabre, Alessandro Plebani, Stéphanie Boisson-Dupuis, Capucine Picard, Alain Fischer, Alain Israel, Laurent Abel, Michel Veron, Jean-Laurent Casanova, Fabrice Agou, Jacinta Bustamante
Journal: Blood
Blood (2011) 118 (4): 926–935.
https://doi.org/10.1182/blood-2010-10-315234
Published: 2011
Includes: Supplemental data
Journal Articles

Improved Outcome with Total Therapy 3 (TT3) In Comparison with Total Therapy 2 (TT2) Can Be Traced to GEP70-Defined High-Risk Disease with Trisomy of 1q21 and Modest but Not Marked Hyper-Activation of the Proteasome Gene PSMD4

John Shaughnessy, Jr., PhD, Pingping Qu, Erming Tian, Bijay Nair, MD, MPH, Sarah Waheed, MD, Yazan Alsayed, MD, Frits van Rhee, MD, PhD, John Crowley, PhD, Bart Barlogie, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 303.
https://doi.org/10.1182/blood.V116.21.303.303
Published: 2010
Journal Articles

Xanthohumol: A New Potential Proteasome Inhibitor That Activates the Pro-Apoptotic Arm of the Unfolded Protein Response in B-CLL Cells.

Sofie Lust, Barbara VanHoecke, PhD, Mireille Van Gele, PhD, Jerina Boelens, MD, Jan Philippé, MD PhD, Petra Vincken, Marc Bracke, MD PhD, Martine Poelman, MD, Fritz Offner, MDPhD
Journal: Blood
Blood (2007) 110 (11): 4694.
https://doi.org/10.1182/blood.V110.11.4694.4694
Published: 2007
Journal Articles

E3 Ubiquitin Ligase Rnf41 (FLRF/Nrdp1) Regulates Steady-State Cytokine Receptor Levels in Multipotent Hematopoietic Progenitors.

Xin Jing, MD, PhD, Luis Dabul, B.Sc., Laila O. Mnayer, Ph.D, Roland Jurecic, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 461.
https://doi.org/10.1182/blood.V104.11.461.461
Published: 2004
Journal Articles

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

Laurence Catley, Ellen Weisberg, Yu-Tzu Tai, Peter Atadja, Stacy Remiszewski, Teru Hideshima, Nicholas Mitsiades, Reshma Shringarpure, Richard LeBlanc, Dharminder Chauhan, Nikhil C. Munshi, Robert Schlossman, Paul Richardson, James Griffin, Kenneth C. Anderson
Journal: Blood
Blood (2003) 102 (7): 2615–2622.
https://doi.org/10.1182/blood-2003-01-0233
Published: 2003