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Journal Articles

Results from CARTITUDE-1: A Phase 1b/2 Study of JNJ-4528, a CAR-T Cell Therapy Directed Against B-Cell Maturation Antigen (BCMA), in Patients with Relapsed and/or Refractory Multiple Myeloma (R/R MM)

Deepu Madduri, MD, Saad Z. Usmani, MD, Sundar Jagannath, Indrajeet Singh, PhD, Enrique Zudaire, PhD, Tzu-Min Yeh, Alicia J. Allred, PhD, Arnob Banerjee, MD, Jenna D. Goldberg, MD, Jordan M Schecter, MD, Sen Zhuang, Jeffrey R. Infante, MD, Syed Rizvi, Xiaohu (Frank) Fan, MD PhD, Andrzej Jakubowiak, MD PhD, Jesus G. Berdeja, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 577.
https://doi.org/10.1182/blood-2019-121731
Published: 2019
Journal Articles

Perceptions of Community Hematologists/Oncologists on the Potential of Data Presented at ASH 2018 and ASCO 2019 to Alter the Standard of Care for Multiple Myeloma Treatment

Ajeet Gajra, MD FACP, Richard Sweat, PhD, Yolaine Jeune-Smith, PhD, Bruce Feinberg, DO
Journal: Blood
Blood (2019) 134 (Supplement_1): 5822.
https://doi.org/10.1182/blood-2019-129502
Published: 2019
Journal Articles

Selinexor, Pomalidomide, and Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

Christine I Chen, MD, Nizar Bahlis, MD, Cristina Gasparetto, MD, Sascha A Tuchman, MD, Brea C. Lipe, MD, Muhamed Baljevic, MD, Rami Kotb, MD, Heather J. Sutherland, MD PhD, William I. Bensinger, Michael Sebag, MD PhD, Richard Leblanc, MDFRCPC, Christopher P Venner, MD, Gary J. Schiller, MD, Suzanne Lentzsch, MD PhD, Natalie Scott Callander, MD, Heidi Sheehan, Yi Chai, Kazuharu Kai, MD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD, Darrell J White, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 141.
https://doi.org/10.1182/blood-2019-122907
Published: 2019
Journal Articles

Fractionated Dosing of CLR 131 in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

Sikander Ailawadhi, MD, Patrick J. Stiff, MD, Emad Ibrahim, MBBCh, MD, Anusha Vallurupalli, MBBS, Elizabeth H. Cull, MD, Damian J. Green, MD, Kate Oliver, BS, Jarrod Longcor
Journal: Blood
Blood (2019) 134 (Supplement_1): 144.
https://doi.org/10.1182/blood-2019-131014
Published: 2019
Journal Articles

Effect of Prior Therapy on the Efficacy and Safety of Oral Selinexor in Patients with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): A Post-Hoc Analysis of the Sadal Study

Federica Cavallo, MD PhD, George A Follows, MD PhD, Andre Goy, MD, Joost Vermaat, MD PhD, Rene-Olivier Casasnovas, MD, Orly Lavee, MD, Marie Maerevoet, MD, Josée M Zijlstra, MD PhD, Sameer Bakhshi, MD, Reda Bouabdallah, Sylvain Choquet, MD, Ronit Gurion, MD, Brian T. Hill, MD, Ulrich Jaeger, MD, Juan-Manuel Sancho, MD PhD, Michael W. Schuster, MD, Catherine Thieblemont, MD PhD, Fatima De la Cruz, MD, Miklos Egyed, MD PhD, Sourav Mishra, Fritz Offner, MD, Theodoros P. Vassilakopoulos, MD PhD, Krzysztof Warzocha, Daniel McCarthy, Xiwen Ma, Kelly Corona, Jean-Richard Saint-Martin, Anita Joshi, PhD, Jatin Shah, MD, Eric Van Den Neste, MD, Miguel A Canales, MD PhD, Nagesh Kalakonda, FRCPath PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5333.
https://doi.org/10.1182/blood-2019-122900
Published: 2019
Journal Articles

Follicular Lymphoma Frontline Immuno-Chemotherapy: Survival Outcomes and Infection-Related Morbidity

Faouzi Djebbari, Furqaan Kaji, Louise Stanton, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Toby A. Eyre
Journal: Blood
Blood (2019) 134 (Supplement_1): 5884.
https://doi.org/10.1182/blood-2019-122213
Published: 2019
Journal Articles

Patient Perception on Health Care Delivery for Sickle Cell Disease and Opportunities for Quality Improvement

Ofelia A. Alvarez, MD, Sandra Echenique, Hector Rodriguez-Cortes, MD, Thomas J. Harrington, MD, E. Leila Jerome Clay, MD MCTS, FAAP, Vandy Black, MDMSc, Mary Murph, Christopher Wells, Ifeyinwa (ify) Osunkwo, MDMPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 5862.
https://doi.org/10.1182/blood-2019-123215
Published: 2019
Journal Articles

Hydroxyurea Prescription Fills and Adherence, Among Pediatric and Adult Medicaid Eligible Patients with Sickle Cell Disease in North Carolina

Nirmish Shah, Christian Douglas, DrPH, Nancy Crego, PhD RN, CCRN, CHSE, Emily Bonnabeau, BA, Marian Earls, MD, Kern Eason, MBA, Elizabeth Merwin, PhD RN, FAAN, Paula Tanabe, PhDRN
Journal: Blood
Blood (2019) 134 (Supplement_1): 3391.
https://doi.org/10.1182/blood-2019-124442
Published: 2019
Journal Articles

Overall Survival of Triple Class Refractory, Penta-Exposed Multiple Myeloma (MM) Patients Treated with Selinexor Plus Dexamethasone or Conventional Care: A Combined Analysis of the STORM and Mammoth Studies

Luciano J. Costa, MD PhD, Parameswaran Hari, MBBS, MD, Shaji K. Kumar, MD, Shijie Tang, Ujjawal H Gandhi, PhDMBBS, Jatin J. Shah, MD, Sundar Jagannath, MD, Ajai Chari, MD, Arjun Lakshman, MBBS, Sharon Shacham, PhD MBA, Xiwen Ma, David S. Siegel, Noa Biran, MD, Sagar Lonial, Paul G. Richardson, MD, Michael G. Kauffman, MD PhD, Ehsan Malek, MD, Kelly N. Godby, MD, Mark A. Fiala, BS, Saurabh Chhabra, MD, Saad Z. Usmani, MD, Natalie Scott Callander, MD, Yubin Kang, MD, Amarendra K. Neppalli, MD, Elvira Umyarova, MD, Robert F. Cornell, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3125.
https://doi.org/10.1182/blood-2019-124991
Published: 2019
Journal Articles

A Phase 1b/2 Study of Selinexor, Carfilzomib, and Dexamethasone (SKd) in Relapsed/ Refractory Multiple Myeloma (RRMM)

Cristina Gasparetto, MD, Gary J. Schiller, MD, Natalie Scott Callander, MD, Suzanne Lentzsch, MD PhD, Sascha A Tuchman, MD, Nizar Bahlis, MD, Darrell J White, MD, Christine I Chen, MD, Heather J. Sutherland, MD PhD, Muhamed Baljevic, MD, Rami Kotb, MD, Richard Leblanc, MDFRCPC, Michael Sebag, MD PhD, Christopher P Venner, MD, William I. Bensinger, Heidi Sheehan, Yi Chai, Kazuharu Kai, MD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD, Brea C. Lipe, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3157.
https://doi.org/10.1182/blood-2019-122902
Published: 2019
Journal Articles

Eltanexor (KPT-8602), a Second-Generation Selective Inhibitor of Nuclear Export (SINE) Compound, in Patients with Higher-Risk Myelodysplastic Syndrome

Sangmin Lee, MD, Bhavana Bhatnagar, DO, Sanjay R Mohan, MD MSCI, William T. Senapedis, Jr., Erkan Baloglu, PhD, Hongwei Wang, MD, Jatin J. Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2997.
https://doi.org/10.1182/blood-2019-124136
Published: 2019
Journal Articles

A Machine Learning Approach Identifies a 30-Gene Model That Predicts Sensitivity to Selinexor in Multiple Myeloma

Alessandro Lagana, PhD, Sherry Bhalla, Adolfo Aleman, Anna Huo-Chang Mei, MS, Violetta Leshchenko, PhD, Yosef Landesman, PhD, David Melnekoff, BS,MS, Itai Beno, PhD, Deepu Madduri, MD, Joshua R Richter, MD, Ajai Chari, MD, Hearn Jay Cho, MD PhD, Sundar Jagannath, MD, Joel Dudley, PhD, Samir Parekh, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3101.
https://doi.org/10.1182/blood-2019-130753
Published: 2019
Journal Articles

Safety and Efficacy of the Combination of Selinexor, Lenalidomide and Dexamethasone (SRd) in Patients with Newly Diagnosed Multiple Myeloma

Darrell J White, MD, Suzanne Lentzsch, MD PhD, Cristina Gasparetto, MD, Nizar Bahlis, MD, Christine I Chen, MD, Brea C. Lipe, MD, Gary J. Schiller, MD, Sascha A Tuchman, MD, Heather J. Sutherland, MD PhD, Rami Kotb, MD, Richard Leblanc, MDFRCPC, Michael Sebag, MD PhD, Christopher P Venner, MD, Natalie Scott Callander, MD, William I. Bensinger, Heidi Sheehan, Yi Chai, Kazuharu Kai, MD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD, Muhamed Baljevic, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3165.
https://doi.org/10.1182/blood-2019-124370
Published: 2019
Journal Articles

Influence of Cytogenetics in Patients with Relapsed Refractory Multiple Myeloma Treated with Oral Selinexor and Dexamethasone: A Post-Hoc Analysis of the STORM Study

Ajay K Nooka, MDMPH, Andrew J. Yee, MD, Carol Ann Huff, MD, Dan T. Vogl, MD, Maria Gavriatopoulou, MD, Ajai Chari, MD, Philippe Moreau, MD, David Dingli, MD PhD, Craig E. Cole, MD, Sagar Lonial, Meletios A. Dimopoulos, MD, Joshua R Richter, MD, Ravi Vij, MBBS, Sascha A Tuchman, MD, Marc S Raab, MD PhD, Noa Biran, MD, David S. Siegel, Paul G. Richardson, MD, Jianjun Liu, Anita Joshi, PhD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G. Kauffman, MD PhD, Sundar Jagannath, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1872.
https://doi.org/10.1182/blood-2019-122908
Published: 2019
Journal Articles

Beliefs and Practices Among Adults with Sickle Cell Disease Regarding Reproductive Health Decisions and Family Planning

Laura Ibidunni, Kristin Paulyson Nunez, MS, CGC, Jude C Jonassaint, RN, Laura De Castro, MD MHSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2101.
https://doi.org/10.1182/blood-2019-122255
Published: 2019
Journal Articles

Selinexor-Containing Regimens for the Treatment of Patients with Multiple Myeloma Refractory to Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

Ajai Chari, MD, Dan T. Vogl, MD, Sundar Jagannath, MD, Jagoda K. Jasielec, MD, Andrew DeCastro, PhD, TJ Unger, PhD, Jatin Shah, MD, Andrzej Jakubowiak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1854.
https://doi.org/10.1182/blood-2019-128887
Published: 2019
Journal Articles

A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma

Karen L Burger, PhD, Mark B. Meads, PhD, Anders Berglund, Paula S. Oliveira, Allison Distler, Praneeth Reddy Sudalagunta, PhD, Timothy Jacobson, Jamie Teer, PhD, Eric A. Welsh, PhD, Hongyue Dai, PhD, John M. Koomen, PhD, Alugubelli Raghunandan Reddy, Gabriel De Avila, Alexandre Tungesvik, MD, William Roush, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD, John Cleveland, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5537.
https://doi.org/10.1182/blood-2019-130830
Published: 2019
Journal Articles

Infection-Related Morbidity Reduced Overall Survival in a Large Real-World Cohort of Transplant Ineligible Newly Diagnosed Myeloma Patients Treated with UK Standard of Care

Faouzi Djebbari, Fotios Panitsas, Catherine Prodger, Fearn Davies, Kieran Burton, Akhil Khera, Grant Vallance, B.Sc., PhD, Sally Moore, Jaimal Kothari, Andy Peniket, MD, Karthik Ramasamy, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4768.
https://doi.org/10.1182/blood-2019-128139
Published: 2019
Journal Articles

Response to Therapy and the Effectiveness of Treatment with Selinexor and Dexamethasone in Patients with Penta-Exposed Triple-Class Refractory Myeloma Who Had Plasmacytomas

Andrew J. Yee, MD, Carol Ann Huff, MD, Ajai Chari, MD, Dan T. Vogl, MD, Maria Gavriatopoulou, MD, Ajay K Nooka, MDMPH, Philippe Moreau, MD, David Dingli, MD PhD, Craig E. Cole, MD, Sagar Lonial, Meletios A. Dimopoulos, MD, Joshua R Richter, MD, Ravi Vij, MBBS, Sascha A Tuchman, MD, James E. Hoffman, MD, Luciano J. Costa, MD PhD, Terri L Parker, MD, Philip Vlummens, MD, Chantal Doyen, MD, Noa Biran, MD, David S. Siegel, Jatin Shah, MD, Carla Picklesimer, Jean-Richard Saint-Martin, Lingling Li, Michael G. Kauffman, MD PhD, Sharon Shacham, PhD MBA, Paul G. Richardson, MD, Sundar Jagannath, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3140.
https://doi.org/10.1182/blood-2019-129038
Published: 2019
Journal Articles

Programmed Cell Death Receptor (PD-1), PD-1 Ligand (PD-L1) Expression in Philadelphia Chromosome Negative Myeloid Neoplasms

Chi Chen, MD PhD, Anita Pandey, MBBS, MD, Ajay Kundra, MD, Sreenath Kodali, MBBS, MD, Ching Wong, MD, Tony W. Cheung, MD, Vladimir K. Gotlieb, MD, Gardith Joseph, MD, Sophia Tribie, Jen-Chin Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4302.
https://doi.org/10.1182/blood-2018-99-112393
Published: 2018