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Journal Articles

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Erica B. Esrick, MD, Maureen Achebe, MD MPH, Myriam Armant, PhD, Pablo Bartolucci, MD PhD, Marioara Felicia Ciuculescu, MD, Heather Daley, Colleen Dansereau, MSN, RN, CPN, Giuseppe Di Caprio, PhD, Bronner Goncalves, MD PhD, Nicolas Hebert, Matthew M Heeney, MD, John M. Higgins, MD PhD, Leslie E. Lehmann, MD, John P Manis, MD, Olivier Negre, PhD, Sarah Nikiforow, MD PhD, Ethan Schonbrun, PhD, David K. Wood, PhD, David A. Williams, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-5.
https://doi.org/10.1182/blood-2019-132745
Published: 2019
Journal Articles

CD19 CAR T-Cell Therapy in Patients with Relapse/Refractory DLBCL: Retrospective Analysis of the Eligibility Criteria

Jérôme Paillassa, MD, Roberta Di Blasi, Sylvie Chevret, Sophie Bernard, Michael Darmon, MD PhD, Veronique Meignin, Bénédicte Deau-Fischer, Vincent Camus, Rene-Olivier Casasnovas, MD, Guillaume Cartron, Driss Chaoui, Vincent Delwail, MD, Pierre Feugier, MD PhD, Luc Mathieu Fornecker, MD PhD, Emmanuel Gyan, MD PhD, Corinne Haioun, MD PhD, Frederique Kuhnowski, MD, Jean Valère Malfuson, MD, Jean-Pierre Marolleau, MD PhD, Veronique Morel, Gandhi Damaj, MD PhD, Anne Quinquenel, MD, Sophie Rigaudeau, MD, Celia Salanoubat, Géraldine Salmeron, David Sibon, MD PhD, Elie Azoulay, MD PhD, Maxime Berquier, Catherine Thieblemont, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2887.
https://doi.org/10.1182/blood-2019-129532
Published: 2019
Journal Articles

Transcranial Doppler Screening in Children with Sickle Cell Anemia Is Feasible in Central India and Reveals High Risk of Stroke

Dipty Jain, MD, Kavitha Ganesan, MBBS, Sati Sahota, Deepika S. Darbari, MD, Lakshmanan Krishnamurti, MD, Fenella Jane Kirkham, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2279.
https://doi.org/10.1182/blood-2019-131416
Published: 2019
Journal Articles

Cerebral and Skeletal Muscle Tissue Oxygenation during Exercise in Children with Sickle Cell Anemia

Christina M Barriteau, MD, Abraham Chiu, PhD, Mark Rodeghier, PhD, Robert I Liem, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2280.
https://doi.org/10.1182/blood-2019-124262
Published: 2019
Journal Articles

MetAP2 Inhibition Modifies Hemoglobin S (HbS) to Delay Polymerization and Improve Blood Flow in Sickle Cell Disease

Melanie Demers, PhD, Sarah Sturtevant, BSc, Kevin Guertin, PhD, Dipti Gupta, Kunal Desai, MS, Benjamin Vieira, BS, Alexandra Hicks, PhD, Ayman Ismail, PhD, Yukio Nakamura, MD PhD, Bronner Goncalves, MD PhD, Giuseppe Di Caprio, PhD, Ethan Schonbrun, PhD, Scott Hansen, BS, Martin K. Safo, PhD, David K. Wood, PhD, John M. Higgins, MD PhD, David R. Light, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2260.
https://doi.org/10.1182/blood-2019-128727
Published: 2019
Journal Articles

Double-Blind, Randomized Study of Canakinumab Treatment in Pediatric and Young Adult Patients with Sickle Cell Anemia

David C Rees, Yurdanur Kilinc, MD, Selma Unal, Carlton Dampier, MD, Betty S. Pace, MD, Banu Kaya, MD, Sara Trompeter, MBChB BSc MRCPCH FRCPath MSc, Isaac Odame, Johnny N Mahlangu, MBBCH, MMed, FCPath, Sule Unal, MD, Julie Brent, MD, Regine Grosse, MD, Beng R. Fuh, MD, Baba PD Inusa, MD, Ariel Koren, MD, Carina Levin, MD PhD, Steven Mortier, Elizabeth McNamara, Yue Li, Stephen John Oliver, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 615.
https://doi.org/10.1182/blood-2019-123355
Published: 2019
Journal Articles

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

Rimi Hazra, Samit Ghosh, Bethany Flage, Matthew Crouthamel, Clark Pan, Xiuxia Sun, Bohong Zhang, Joseph Sypek, Solomon Fiifi Ofori-Acquah
Journal: Blood
Blood (2019) 134 (Supplement_1): 74.
https://doi.org/10.1182/blood-2019-127198
Published: 2019
Journal Articles

Veno-Occlusive Disease (VOD) after Hematopoietic Stem Cell Transplant (HSCR): Always a Catastrophic Illness?

Paolo Bernasconi, MD, Anna Amelia Colombo, MD, Daniela Caldera, MD, Oscar Borsani, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5649.
https://doi.org/10.1182/blood-2019-125608
Published: 2019
Journal Articles

Biomarkers of Cardiopulmonary, Renal, and Liver Dysfunction in an Adult Sickle Cell Disease Cohort

Xu Zhang, PhD, Binal N. Shah, Roberto Machado, MD, Santosh L. Saraf, MD, Victor R Gordeuk, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3574.
https://doi.org/10.1182/blood-2019-131813
Published: 2019
Journal Articles

Use of Fluid and Oxygen Therapy in Normoaxaemic Paediatric Patients Presenting with Acute Sickle Vaso-Occlusive Episodes Requiring Hospital Admission and Analysis of Clinical Outcome

Zain Butt, BSc, Subarna Chakravorty, PhDFRCPath MRCP MRCPCH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4844.
https://doi.org/10.1182/blood-2019-125708
Published: 2019
Journal Articles

Identification of the Pitfalls in the Attempted Use of Extracorporeal Membrane Oxygenation in an Adult Patient with Sickle Cell Disease and Severe Acute Chest Syndrome

Mira T Tanenbaum, BA, Anna Shvygina, BS, Vaishnavi Sridhar, BS, Jennifer E. Vaughn, MD MSPH, Mark Joseph, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4854.
https://doi.org/10.1182/blood-2019-131561
Published: 2019
Journal Articles

A Novel Approach to Assess Capacities of Red Cells in Dissolving Oxygen and Carrying Oxygen Based on a Portable Near-Infrared Spectroscopy Device

Ting Li, PhD, Yue Zhao, Master, Yunlong Sun, Master, Kai Li, Master, Wenjie Li, Meixue Duan, PhD, Chenyang Gao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4792.
https://doi.org/10.1182/blood-2019-124003
Published: 2019
Journal Articles

Lower Oxygen Saturation in the Internal Cerebral Vein of Patients with Sickle Cell Disease Revealed By Qsm-MRI

Jian Shen, MSc, Thomas Coates, MD, John C Wood, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 984.
https://doi.org/10.1182/blood-2019-131968
Published: 2019
Journal Articles

Pulmonary Function Abnormalities in Adults with Sickle Cell Anemia

Adam Rock, MD, Binal N. Shah, PhD, Jin Han, PharmD, PhD, Rasha Raslan, MD, Michel Gowhari, DO, Shivi Jain, MD, Xu Zhang, PhD, Robert E. Molokie, MD, Victor R. Gordeuk, MD, Santosh L. Saraf, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3664.
https://doi.org/10.1182/blood-2018-99-114820
Published: 2018
Journal Articles

Hypofibrinogenemia in Patient with Extended Exposure to Argatroban Therapy

Mustafa Saudi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5035.
https://doi.org/10.1182/blood-2018-99-117765
Published: 2018
Journal Articles

Trends in Vital Signs in Relation to Patient Outcomes during Induction Phase in Treatment of Acute Leukemia

Katharine McLaughlin, Amanda Stojcevski, B.Sc, Abdulkadir Hussein, B.Sc. (Trieste), M.Sc., PhD (Alberta), Indryas L. Woldie, MD, Caroline Hamm, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5195.
https://doi.org/10.1182/blood-2018-99-116891
Published: 2018
Journal Articles

Reduced Cerebral Metabolic Rate of Oxygen in Adults with Sickle Cell Disease

Lena Vaclavu, Esben Thade Petersen, PhD, Ed T VanBavel, PhD, Charles BL Majoie, MD PhD, Aart J Nederveen, PhD, Bart J. Biemond, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 11.
https://doi.org/10.1182/blood-2018-99-116194
Published: 2018
Journal Articles

LC-MS Analysis of Anti-Sickling Compounds in Cord Blood Derived RBCs Demonstrates Modification of Fetal Hemoglobin and Globin Chain Binding Preferences

Benjamin Vieira, Vu P. Hong, Kunal Desai, Martin K. Safo, David R. Light
Journal: Blood
Blood (2018) 132 (Supplement 1): 1074.
https://doi.org/10.1182/blood-2018-99-116319
Published: 2018
Journal Articles

Predictors of Adverse Outcome in Sickle Cell Disease Patients from Oman

Salam Alkindi, FRCP, BA, MBBChir, Salma AlJadidi, Safa Al Adawi, Anil Pathare, MD PhD FCPS, MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4915.
https://doi.org/10.1182/blood-2018-99-118304
Published: 2018
Journal Articles

Hemolysis and Tricuspid Regurgitation Jet Velocity Predict Mortality in Patients with Sickle Cell Disease

Payal Shah, MS, Adam Bush, PhD, Silvie Suriany, MS, Honglei Liu, MS, Henry J Forman, PhD, Patjanaporn Chalacheva, PhD, Wanwara Thuptimdang, MS, John Sunwoo, MS, Saranya Veluswamy, MD, Christopher Clement Denton, MD, Maha Khaleel, MD, Roberta Miyeko Kato, MD, Ajay Perumbeti, MD, Richard Sposto, PhD, Michael Khoo, PhD, Thomas D. Coates, MD, John C Wood, MD PhD, Jon A Detterich, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1086.
https://doi.org/10.1182/blood-2018-99-119587
Published: 2018