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Journal Articles

Heme-Mediated Tau Phosphorylation Is Critical for Neuroaxonal Damage and Cognitive Impairment in Sickle Cell Disease

Nandinii Sekar, Shane C Lenhart, Paritosh Mondal, Lesley Foley, Samit Ghosh, Enrico M Novelli, T Kevin Hitchens, Xiaoming Hu, Rimi Hazra
Journal: Blood
Blood (2024) 144 (Supplement 1): 624.
https://doi.org/10.1182/blood-2024-211179
Published: 2024
Journal Articles

Heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice

Qiyang Chen, Rimi Hazra, Danielle Crosby, Diane Lenhart, Shane C. Lenhart, Paritosh Mondal, Yingze Zhang, Seyed M. Nouraie, Roderick J. Tan, Charles T. Esmon, L. Vijay Mohan Rao, Kang Kim, Samit Ghosh
Journal: Blood
Blood (2024) 144 (5): 552–564.
https://doi.org/10.1182/blood.2023023528
Published: 2024
Includes: Supplemental data
Journal Articles

White Matter Injury in Sickle Cell Mice Is Associated with Reduced Neurocognitive Function and Activation of Astrocytes

Rimi Hazra, Hongjan Pu, Lesley M. Foley, T. Kevin Hitchens, Lynda Little-Ihrig, Samit Ghosh, Solomon Fiifi Ofori-Acquah, Xiaoming Hu, Enrico M. Novelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 441–442.
https://doi.org/10.1182/blood-2022-169094
Published: 2022
Journal Articles

Heme Induced Progressive Loss of Endothelial Protein C Receptor Promotes Development of Chronic Kidney Disease in Sickle Cell Disorders

Rimi Hazra, Qiyang Chen, Danielle Crosby, Diane Lenhart, Roderick Tan, Kang Kim, L. Vijaya Mohan Rao, Solomon Fiifi Ofori-Acquah, Samit Ghosh
Journal: Blood
Blood (2021) 138 (Supplement 1): 188.
https://doi.org/10.1182/blood-2021-154027
Published: 2021
Journal Articles

Hemopexin deficiency promotes acute kidney injury in sickle cell disease

Clinical Trials & Observations Brief Report
Solomon F. Ofori-Acquah, Rimi Hazra, Oluwaseun O. Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel B. Ackah, Diane Lenhart, Roderick J. Tan, Dario A. Vitturi, Vivian Paintsil, Ellis Owusu-Dabo, Samit Ghosh, in collaboration with the SickleGenAfrica Network
Journal: Blood
Blood (2020) 135 (13): 1044–1048.
https://doi.org/10.1182/blood.2019002653
Published: 2020
Includes: Supplemental data
Journal Articles

Hemopexin Replacement Therapy Protects Sickle Cell Disease Mice from Acute Kidney Injury

Samit Ghosh, Oluwaseun Orikogbo, Rimi Hazra, Bethany Flage, Danielle Crosby, Solomon Fiifi Ofori-Acquah
Journal: Blood
Blood (2019) 134 (Supplement_1): 78.
https://doi.org/10.1182/blood-2019-127161
Published: 2019
Journal Articles

Targeted Therapy of Acute Chest Syndrome with Recombinant Heme Oxygenase-1 Revealed By the Resistance of Young Transgenic Sickle Cell Mice to Heme-Induced Acute Lung Injury

Rimi Hazra, Samit Ghosh, Bethany Flage, Matthew Crouthamel, Clark Pan, Xiuxia Sun, Bohong Zhang, Joseph Sypek, Solomon Fiifi Ofori-Acquah
Journal: Blood
Blood (2019) 134 (Supplement_1): 74.
https://doi.org/10.1182/blood-2019-127198
Published: 2019
Journal Articles

Enhanced Renal Clearance of Heme Triggers Acute Kidney Injury in Sickle Cell Disease

Samit Ghosh, PhD, Vivian Paintsil, MD, Rimi Hazra, PhD, Oluowaseun O. Orikogbo, Bethany Flage, Ezekiel Bonwin Ackah, Ellis Owusu-Dabo, PhD, Solomon Fiifi Ofori-Acquah, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 441.
https://doi.org/10.1182/blood.V130.Suppl_1.441.441
Published: 2017
Journal Articles

Prophylactic Nrf2 Activation Halts Progression of the Severe Adult Phenotype of Sickle Cell Disease in Transgenic Mice

Samit Ghosh, PhD, Chibueze A. Ihunnah, PhD, Rimi Hazra, PhD, Amma T. Owusu-Ansah, MD, Jason M Hansen, PhD, David R. Archer, PhD, Solomon Fiifi Ofori-Acquah, PhD
Journal: Blood
Blood (2015) 126 (23): 3394.
https://doi.org/10.1182/blood.V126.23.3394.3394
Published: 2015
Journal Articles

Targeted Disruption of Nrf2 in Non-Hematopoietic Tissues Exacerbates Hemolysis and Accelerates Chronic Lung Disease in Transgenic Sickle Cell Anemia Mice

Samit Ghosh, PhD, Jason Hansen, PhD, Rimi Hazra, PhD, David R. Archer, PhD, Solomon F. Ofori-Acquah, PhD
Journal: Blood
Blood (2014) 124 (21): 456.
https://doi.org/10.1182/blood.V124.21.456.456
Published: 2014