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Journal Articles

Cytomegalovirus Infection in Bone Marrow-Derived Mesenchymal Stem Cells: Implications for Functions and Exploration of Relevant Mechanisms

Weiran Lv, Zhiping Fan, MD, Fen Huang, MD, Na Xu, MD, Li Xuan, MD, Ren Lin, MD, Ke Zhao, Qifa Liu, MD

Blood (2019) 134 (Supplement_1): 5005.

https://doi.org/10.1182/blood-2019-125318

Published: 2019

Journal Articles

Mechanical Loading Shows Anti-Myeloma Effects While Rescuing Bone Loss with Net Bone Formation in a Myeloma Bone Disease Murine Model

Fani Ziouti, Maximilian Rummler, Andreas Brandl, PhD, Andreas Beilhack, MD, Maureen Lynch, PhD, Bettina Willie, PhD, Franziska Jundt, MD

Blood (2018) 132 (Supplement 1): 3164.

https://doi.org/10.1182/blood-2018-99-116796

Published: 2018

Journal Articles

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Simon Haas, PhD, Chiara Baccin, Jude Al-Sabah, Lars Velten, PhD, Steinmetz Lars, PhD, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 876.

https://doi.org/10.1182/blood-2018-99-118479

Published: 2018

Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Blood (2018) 132 (Supplement 1): 4246.

https://doi.org/10.1182/blood-2018-99-119974

Published: 2018

Journal Articles

Runx2 Deficiency in Committed Osteoblasts Promotes Myeloma Cell Homing to and Progression in New Bone Sites

Xiaoxuan Xu, Juan Li, MD, Timothy Trotter, Pramod Gowda, Xiaoxiao Hao, Jacob Calahan, Racquel Innis-Shelton, MD, Amjad Javed, Yang Yang, MD

Blood (2017) 130 (Supplement 1): 126.

https://doi.org/10.1182/blood.V130.Suppl_1.126.126

Published: 2017

Journal Articles

AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche

Ben Doron, BS, Sherif Abdelhamed, PhD, Ryan M Mulqueen, B.S., Julja Burchard, M.S., Andrew Adey, PhD, Peter Kurre, MD

Blood (2017) 130 (Supplement 1): 1197.

https://doi.org/10.1182/blood.V130.Suppl_1.1197.1197

Published: 2017

Journal Articles

Adipocyte Induced Antagonism of ALL Growth Highlights a Novel Inhibitory Niche and Potential Therapeutic Opportunity

Nicholas Warrick, BSc, Farideh Miraki-Moud, PhD, A Aicher, Linda Ariza McNaughton, Pedro Casado-Izquierdo, Ai Nagano, PhD, Rebecca Carroll, Dominique Bonnet, PhD, John G. Gribben, MDDSc FMedSci, Bela Patel, MD

Blood (2017) 130 (Supplement 1): 371.

https://doi.org/10.1182/blood.V130.Suppl_1.371.371

Published: 2017

Journal Articles

Does Osteogenic Potential of Clonal Human Bone Marrow Mesenchymal Stem/Stromal Cells Correlate with Their Vascular Supportive Ability?

Suzanne M Watt, PhDFRCPath, Alison Merryweather-Clarke, PhD, David Cook, PhD, Barbara Joo Lara, BSc, MRes, Emmanouela Repapi, PhD, Neil Ashley, PhD, Peng Hua, PhD

Blood (2017) 130 (Supplement 1): 4948.

https://doi.org/10.1182/blood.V130.Suppl_1.4948.4948

Published: 2017

Journal Articles

p62-ZZ Domain Signaling Inhibition Rescues MM-Induced Epigenetic Repression at the Runx2 promoter and Allows Osteoblast Differentiation of MM Patient Pre-Osteoblasts In Vitro

Rebecca Silbermann, MD, Juraj Adamik, PhD, Dan Zhou, Xiang-Qun Xie, MD PhD EMBA, Noriyoshi Kurihara, DDS, PhD, G. David Roodman, MD PhD, Deborah Lynn Galson, PhD

Blood (2016) 128 (22): 4410.

https://doi.org/10.1182/blood.V128.22.4410.4410

Published: 2016

Journal Articles

LIGHT (TNFSF14) Increases Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells Via LTβR

Hawk Kim, Sook-Kyoung Heo, PhD, Eui-Kyu Noh, PhD, Gi-Dong Gwon, Jae-Cheol Jo, MD PhD, Yunsuk Choi, MD PhD, Jinny Park

Blood (2016) 128 (22): 4546.

https://doi.org/10.1182/blood.V128.22.4546.4546

Published: 2016

Journal Articles

Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients

Syed Mehdi, Sharmin Khan, Wen Ling, Randal S Shelton, Joshua Epstein, DSc, Ricky D Edmondson, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Faith E Davies, MD, Bart Barlogie, MD PhD, Gareth J Morgan, MD PhD, Shmuel Yaccoby, PhD

Blood (2016) 128 (22): 3304.

https://doi.org/10.1182/blood.V128.22.3304.3304

Published: 2016

Journal Articles

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

Renata Scopim-Ribeiro, M.Sc., João Agostinho Machado-Neto, PhD, Paula de Melo Campos, PhD, Adriana da Silva Santos Duarte, PhD, Priscila Santos Scheucher, PhD, Amélia Góes, PhD, Sara Teresinha Olalla Saad, MD, PhD, Belinda Pinto Simoes, MD, PhD, Eduardo Magalhães Rego, MD, PhD, Fabiola Traina, MD, PhD

Blood (2015) 126 (23): 2772.

https://doi.org/10.1182/blood.V126.23.2772.2772

Published: 2015

Journal Articles

p62-ZZ Domain Inhibition Prevents MM Cell-Induced Epigenetic Changes at the Runx2 and C/EBPb Promoters

Rebecca Silbermann, MD, Juraj Adamik, PhD, Dan Zhou, Xiang-Qun Xie, MD PhD EMBA, G. David Roodman, MD PhD, Noriyoshi Kurihara, DDS, PhD, Deborah Lynn Galson, PhD

Blood (2015) 126 (23): 1796.

https://doi.org/10.1182/blood.V126.23.1796.1796

Published: 2015

Journal Articles

The Clinical Utility of Bone Resorption and Bone Formation Markers in Multiple Myeloma

Shahdabul Faraz, B.S., Roger N Pearse, MD PhD, Sujitha Yadlapati, MBBS, David Jayabalan, BSMS, MSc, Adriana C Rossi, MD MHS, Tomer M Mark, MD MSc, Ruben Niesvizky, MD, Joseph Lane, MD

Blood (2015) 126 (23): 5373.

https://doi.org/10.1182/blood.V126.23.5373.5373

Published: 2015

Journal Articles

Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

Blood (2015) 125 (2): 249–260.

https://doi.org/10.1182/blood-2014-04-572255

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Emerging Roles of Wisp-1 and SFRP4 in Proliferation and Differentiation Potential of Wharton's Jelly Mesenchymal Stem/Stromal Cells

Aristea Batsali, Charalampos Pontikoglou, Emmanuel Agrafiotis, Elisavet Kouvidi, Irene Mavroudi, Athina Damianaki, Maria-Christina Kastrinaki, Helen Papadaki

Blood (2014) 124 (21): 4375.

https://doi.org/10.1182/blood.V124.21.4375.4375

Published: 2014

Journal Articles

Myeloma Cells Switch Osteoblastogenesis to Adipogenesis and Suppress Bone Formation

Jing Yang, PhD, Zhiqiang Liu, PhD, Huan Liu, Jin He, Pei Lin, MD, Robert Z Orlowski, MD, PhD, Larry W Kwak, MD PhD, Qiang Tong, PhD, Robert Gagel, MD

Blood (2014) 124 (21): 3386.

https://doi.org/10.1182/blood.V124.21.3386.3386

Published: 2014

Journal Articles

Sqstm1 Is Required to Retain Hematopoietic Stem Cell/ Progenitors As a Negative Regulator of Macrophage-Dependent Inflammatory Signaling in the Bone Marrow Osteoblastic Niche

Kyung-Hee Chang, PhD, Amitava Sengupta, PhD, Ramesh C Nayak, Angeles Duran, Sang Jun Lee, Ronald Pratt, Ashley Wellendorf, Sarah Hill, Marcus Watkins, Roberto Civitelli, Daniel T Starczynowski, PhD, Maria T Diaz-Meco, Jorge Moscat, Jose A Cancelas, MD PhD

Blood (2014) 124 (21): 350.

https://doi.org/10.1182/blood.V124.21.350.350

Published: 2014

Journal Articles

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

Michaela R. Reagan, Yuji Mishima, Siobhan V. Glavey, Yong Zhang, Salomon Manier, Zhi Ning Lu, Masoumeh Memarzadeh, Yu Zhang, Antonio Sacco, Yosra Aljawai, Jiantao Shi, Yu-Tzu Tai, John E. Ready, David L. Kaplan, Aldo M. Roccaro, Irene M. Ghobrial

Blood (2014) 124 (22): 3250–3259.

https://doi.org/10.1182/blood-2014-02-558007

Published: 2014

Includes: Supplemental data

Journal Articles

Lessons from the Mouse Model

Johanna M. Rommens, PhD, Marina E. Tourlakis, MSc, Holly Liu, BSc, Rikesh Gandhi, MSc, Peter R. Durie, MD

Blood (2013) 122 (21): SCI-35.

https://doi.org/10.1182/blood.V122.21.SCI-35.SCI-35

Published: 2013

NARROW

Cytomegalovirus Infection in Bone Marrow-Derived Mesenchymal Stem Cells: Implications for Functions and Exploration of Relevant Mechanisms

Mechanical Loading Shows Anti-Myeloma Effects While Rescuing Bone Loss with Net Bone Formation in a Myeloma Bone Disease Murine Model

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Runx2 Deficiency in Committed Osteoblasts Promotes Myeloma Cell Homing to and Progression in New Bone Sites

AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche

Adipocyte Induced Antagonism of ALL Growth Highlights a Novel Inhibitory Niche and Potential Therapeutic Opportunity

Does Osteogenic Potential of Clonal Human Bone Marrow Mesenchymal Stem/Stromal Cells Correlate with Their Vascular Supportive Ability?

p62-ZZ Domain Signaling Inhibition Rescues MM-Induced Epigenetic Repression at the Runx2 promoter and Allows Osteoblast Differentiation of MM Patient Pre-Osteoblasts In Vitro

LIGHT (TNFSF14) Increases Survival and Proliferation of Human Bone Marrow-Derived Mesenchymal Stem Cells Via LTβR

Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients

Pharmacological IRS1/2 Inhibition Reduces Cell Viability in BCR-ABL1 Positive Cells

p62-ZZ Domain Inhibition Prevents MM Cell-Induced Epigenetic Changes at the Runx2 and C/EBPb Promoters

The Clinical Utility of Bone Resorption and Bone Formation Markers in Multiple Myeloma

Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

Emerging Roles of Wisp-1 and SFRP4 in Proliferation and Differentiation Potential of Wharton's Jelly Mesenchymal Stem/Stromal Cells

Myeloma Cells Switch Osteoblastogenesis to Adipogenesis and Suppress Bone Formation

Sqstm1 Is Required to Retain Hematopoietic Stem Cell/ Progenitors As a Negative Regulator of Macrophage-Dependent Inflammatory Signaling in the Bone Marrow Osteoblastic Niche

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

Lessons from the Mouse Model

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American Society of Hematology

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American Society of Hematology

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