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Journal Articles

Efficacy and Safety of Luspatercept in Patients Enrolled in the BELIEVE Trial: Data from the Phase 3b Long-Term Rollover Study

Maria Domenica Cappellini, Ali T Taher, Vip Viprakasit, Pencho Georgiev, Kevin H.M. Kuo, Natalia Holot, Valérie Vilmont, Loyse Felber Medlin, Wen-Ling Kuo, Yinzhi Lai, Luciana Moro Bueno, Sujit Sheth
Journal: Blood
Blood (2023) 142 (Supplement 1): 3849.
https://doi.org/10.1182/blood-2023-174089
Published: 2023
Journal Articles

Efficacy and Safety of Luspatercept in Patients with HbE/β-Thalassemia from the BELIEVE Study: A Subgroup Analysis

Kevin H.M. Kuo, Pranee Sutcharitchan, Ping Chong Bee, Lee Ping Chew, Soo Min Lim, Ai Sim Goh, Sadanand Vodala, Wen-Ling Kuo, Yinzhi Lai, Loyse Felber Medlin, Martina Perin, Luciana Moro Bueno, Thomas D Coates, Vip Viprakasit
Journal: Blood
Blood (2023) 142 (Supplement 1): 3848.
https://doi.org/10.1182/blood-2023-174082
Published: 2023
Journal Articles

Luspatercept for the Treatment of Anemia in Non-Transfusion-Dependent β-Thalassemia: Final Safety and Efficacy Data from the BEYOND Trial

Ali T Taher, Vip Viprakasit, Antonis Kattamis, Silverio Perrotta, Paolo Ricchi, John B. Porter, Thomas D Coates, Gian Luca Forni, Khaled M. Musallam, Oriana Esposito, Ana Carolina Giuseppi, Wen-Ling Kuo, Marta Reverte, Richard Wei, Luciana Moro Bueno, Maria Domenica Cappellini
Journal: Blood
Blood (2023) 142 (Supplement 1): 3847.
https://doi.org/10.1182/blood-2023-174097
Published: 2023
Journal Articles

Effect of Luspatercept on Red Blood Cell (RBC) Transfusion Burden, Iron Chelation Therapy (ICT), and Iron Overload in Adults with Transfusion-Dependent β-Thalassemia (TDT) from the BELIEVE Trial: A Long-Term Analysis

Olivier Hermine, Maria Domenica Domenica Cappellini, Ali T. Taher, Thomas D. Coates, Vip Viprakasit, Antonis Kattamis, Jeevan K. Shetty, Marija Bosilkovska Weisskopf, Natalia Holot, Sadanand Vodala, Wen-Ling Kuo, John B. Porter
Journal: Blood
Blood (2022) 140 (Supplement 1): 8215–8217.
https://doi.org/10.1182/blood-2022-156985
Published: 2022
Journal Articles

Erythroid Response in Patients with Non-Transfusion-Dependent β-Thalassemia Treated with Luspatercept: Long-Term Data from the BEYOND Trial

Ali T. Taher, Vip Viprakasit, Maria Domenica Domenica Cappellini, Antonio Piga, John B. Porter, Thomas D. Coates, Khaled M. Musallam, Gian Luca Forni, Jeevan K. Shetty, Marija Bosilkovska Weisskopf, Richard Wei, Wen-Ling Kuo, Antonis Kattamis
Journal: Blood
Blood (2022) 140 (Supplement 1): 8210–8212.
https://doi.org/10.1182/blood-2022-157512
Published: 2022
Journal Articles

Effect of Luspatercept in β-Thalassemia Patients with β0/β0 Genotype: A Subgroup Analysis of the BELIEVE Study

Sujit Sheth, Olivier Hermine, Ali T. Taher, Kevin H.M. Kuo, John B. Porter, Antonio Piga, Thomas D. Coates, Antonis Kattamis, Loyse Felber Medlin, Wen-Ling Kuo, Natalia Holot, Maria Domenica Domenica Cappellini
Journal: Blood
Blood (2022) 140 (Supplement 1): 1946–1948.
https://doi.org/10.1182/blood-2022-157511
Published: 2022
Journal Articles

Luspatercept Improves Quality of Life and Reduces Red Blood Cell Transfusion Burden in Patients with Non-Transfusion-Dependent β-Thalassemia in the BEYOND Trial

Antonis Kattamis, Vip Viprakasit, Maria Domenica Cappellini, Ersi Voskaridou, Antonio Piga, John B. Porter, Thomas D. Coates, Gian Luca Forni, Jeevan K. Shetty, Dimana Miteva, Oriana Esposito, Wen-Ling Kuo, Shien Guo, Christopher Pelligra, Jennifer Lord-Bessen, Aylin Yucel, Ali T. Taher
Journal: Blood
Blood (2021) 138 (Supplement 1): 3081.
https://doi.org/10.1182/blood-2021-148535
Published: 2021
Journal Articles

The Role of PHF19 As a Promoter of Tumorigenicity and Therapeutic Target in Multiple Myeloma

Carolina D. Schinke, MD, Pingping Qu, Shmuel Yaccoby, PhD, Valeriy V Lyzogubov, MD PhD, Veronica MacLeod, Eileen M Boyle, Randal Shelton, Wen Ling, PhD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Bart Barlogie, MD PhD, Frits van Rhee, MD PhD, Brian A Walker, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 508.
https://doi.org/10.1182/blood-2019-130595
Published: 2019
Journal Articles

Evaluating Luspatercept Responders in the Phase 3, Randomized, Double-Blind, Placebo-Controlled BELIEVE Trial of Luspatercept in Adult Beta-Thalassemia Patients (Pts) Who Require Regular Red Blood Cell (RBC) Transfusions

Vip Viprakasit, Ali Taher, Olivier Hermine, John Porter, Antonio Piga, Kevin H. M. Kuo, MDMSc,FRCPC, Thomas Coates, MD, Ersi Voskaridou, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Abderrahmane Laadem, Jeevan K. Shetty, Wen-Ling Kuo, Dimana Miteva, Tatiana Zinger, Daniel Sinsimer, Peter G. Linde, Maria Domenica Cappellini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3545.
https://doi.org/10.1182/blood-2019-122685
Published: 2019
Journal Articles

Effects of Luspatercept on Iron Overload and Impact on Responders to Luspatercept: Results from the BELIEVE Trial

John Porter, Maria Domenica Cappellini, MD, Thomas Coates, MD, Olivier Hermine, Vip Viprakasit, MD DPhil, Ersi Voskaridou, Hong Keng Liew, Silverio Perrotta, Abderrahim Khelif, Antonis Kattamis, Abderrahmane Laadem, Jeevan K. Shetty, Wen-Ling Kuo, Dimana Miteva, Tatiana Zinger, Peter G. Linde, Daniel Sinsimer, Ali Taher
Journal: Blood
Blood (2019) 134 (Supplement_1): 2245.
https://doi.org/10.1182/blood-2019-122561
Published: 2019
Journal Articles

Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Sharmin Khan, Wen Ling, PhD, Randal Shelton, Joshua Epstein, DSc, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Brian A Walker, PhD, Cody Ashby, PhD, Faith E. Davies, MD, Gareth Morgan, MD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1929.
https://doi.org/10.1182/blood-2018-99-116455
Published: 2018
Journal Articles

Single-Cell Analysis of Mesenchymal Stem Cells Reveals Their Molecular and Functional Heterogeneity in Myeloma

Syed J. Mehdi, PhD, Sarah K Johnson, PhD, Joshua Epstein, DSc, Sharmin Khan, Wen Ling, PhD, Randal Shelton, Maurizio Zangari, MD, Pingping Qu, Antje Hoering, Frits van Rhee, MD PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Christopher P. Wardell, PhD, Faith E. Davies, MD, Gareth J. Morgan, MD PhD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1790.
https://doi.org/10.1182/blood.V130.Suppl_1.1790.1790
Published: 2017
Journal Articles

Mesenchymal Stem Cells Preconditioned with Myeloma Cells from High-Risk Patients Support the Growth of Myeloma Cells from Low-Risk Patients

Syed Mehdi, Sharmin Khan, Wen Ling, Randal S Shelton, Joshua Epstein, DSc, Ricky D Edmondson, PhD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Faith E Davies, MD, Bart Barlogie, MD PhD, Gareth J Morgan, MD PhD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2016) 128 (22): 3304.
https://doi.org/10.1182/blood.V128.22.3304.3304
Published: 2016
Journal Articles

ATRA Upregulates Cell Surface CD1D on Myeloma Cells and Sensitizes Them to iNKT Cell-Mediated Lysis

Xin Li, PhD, Tarun K. Garg, PhD, Sarah K. Johnson, PhD, Susann Szmania, BS, Justin Stivers, BS, Wen Ling, MS, Sharmin Khan, MS, Priyangi Malaviarachchi, Bart Barlogie, MD PhD, Frits van Rhee, MD PhD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2014) 124 (21): 2102.
https://doi.org/10.1182/blood.V124.21.2102.2102
Published: 2014
Journal Articles

Sustained Growth of Primary Myeloma Cells in Coculture with Whole Donor Bone Marrow Is Associated with Induced Secretion of the Microenvironmental Mediator of Cytokinesis, Hemicentin-1

Rakesh Bam, PhD, Ricky D Edmondson, PhD, Caleb K Stein, MS, Xin Li, PhD, Wen Ling, MS, Sharmin Khan, MS, Randal S Shelton, B.S., Bart Barlogie, MD, PhD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2014) 124 (21): 3403.
https://doi.org/10.1182/blood.V124.21.3403.3403
Published: 2014
Journal Articles

Mitochondrial DNA copy number and future risk of B-cell lymphoma in a nested case-control study in the prospective EPIC cohort

Fatemeh Saberi Hosnijeh, Qing Lan, Nathaniel Rothman, Chin San Liu, Wen-Ling Cheng, Alexandra Nieters, Per Guldberg, Anne Tjønneland, Daniele Campa, Alessandro Martino, Heiner Boeing, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Vittorio Krogh, Rosario Tumino, Salvatore Panico, Giovanna Masala, Elisabete Weiderpass, José María Huerta Castaño, Eva Ardanaz, Núria Sala, Miren Dorronsoro, J. Ramón Quirós, María-José Sánchez, Beatrice Melin, Ann Sofie Johansson, Johan Malm, Signe Borgquist, Petra H. Peeters, H. Bas Bueno-de-Mesquita, Nick Wareham, Kay-Tee Khaw, Ruth C. Travis, Paul Brennan, Afshan Siddiq, Elio Riboli, Paolo Vineis, Roel Vermeulen
Journal: Blood
Blood (2014) 124 (4): 530–535.
https://doi.org/10.1182/blood-2013-10-532085
Published: 2014
Includes: Supplemental data
Journal Articles

Inhibition Of BTK Activity In Myeloma Cells Within a Supportive Microenvironment Promotes Their Growth But Suppresses Metastasis

Rakesh Bam, BS, Sathisha Upparahalli Venkateshaiah, Ph.D., Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Randal S Shelton, MS, Qing Zhang, PhD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2013) 122 (21): 4432.
https://doi.org/10.1182/blood.V122.21.4432.4432
Published: 2013
Journal Articles

GPRC5D Is a Cell Surface Plasma Cell Marker Whose Expression Is High In Myeloma Cells and Reduced Following Coculture With Osteoclasts

Sathisha Upparahalli venkateshaiah, PhD, Rakesh Bam, BS, Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Shelton Randal S, MS, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2013) 122 (21): 3099.
https://doi.org/10.1182/blood.V122.21.3099.3099
Published: 2013
Journal Articles

Healthy Donor Whole Bone Marrow Cells Preconditioned With Myeloma Patient Serum Support Long-Term Survival Of Primary Myeloma and Reveal Altered Microenvironmental Pathways

Rakesh Bam, BS, Sathisha Upparahalli Venkateshaiah, Ph.D., Xin Li, PhD, Sharmin Khan, MS, Wen Ling, MS, Randal S Shelton, MS, Joshua Epstein, DSc, Bart Barlogie, MD, PhD, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2013) 122 (21): 3118.
https://doi.org/10.1182/blood.V122.21.3118.3118
Published: 2013
Journal Articles

Reduced HMOX1 Expression in Myelomatous Bones Is Associated with Poor Survival and Its Induction Regulates Osteoclastogenesis and Osteoblastogenesis

Xin Li, PhD, Qing Zhang, PhD, Sarah K. Johnson, PhD, Wen Ling, MS, Sharmin Khan, MS, Frits van Rhee, MD, PhD, Saad Z Usmani, MD FACP, Sarah Waheed, MD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD
Journal: Blood
Blood (2012) 120 (21): 1815.
https://doi.org/10.1182/blood.V120.21.1815.1815
Published: 2012