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Journal Articles

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Blood (2020) 136 (4): 387–400.

https://doi.org/10.1182/blood.2019003267

Published: 2020

Includes: Supplemental data

Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD

Blood (2019) 134 (Supplement_1): 4395.

https://doi.org/10.1182/blood-2019-129699

Published: 2019

Journal Articles

The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice

Waitman K. Aumann, MDMS, Sei-Gyung K. Sze, MD, Veerain Gupta, Katelyn Ripple, Sarah Port, Ralph Kehlenbach, PhD, Daniel S. Wechsler, MD PhD, Catherine P. Lavau, DVM, PhD

Blood (2019) 134 (Supplement_1): 1434.

https://doi.org/10.1182/blood-2019-130530

Published: 2019

Journal Articles

HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients

Ana Rio-Machin, BSc, MSc, PhD, Gonzalo Gomez-Lopez, BSc, PhD, Alba Maiques-Diaz, BSc, MSc, PhD, Sara Alvarez, MD PhD, Maria Jose Calasanz, BSc, PhD, Jude Fitzgibbon, Juan C Cigudosa, BSc, PhD

Blood (2016) 128 (22): 2685.

https://doi.org/10.1182/blood.V128.22.2685.2685

Published: 2016

Journal Articles

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Jason E Farrar, MD, Hamid Bolouri, PhD, Rhonda E. Ries, MA, Timothy Junius Triche, Jr., PhD, Emilia L. Lim, PhD, Todd A. Alonzo, PhD, Yussanne Ma, PhD, Richard Moore, PhD, Andrew J. Mungall, Marco A. Marra, PhD, Jaime Guidry Auvil, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Soheil Meshinchi

Blood (2016) 128 (22): 595.

https://doi.org/10.1182/blood.V128.22.595.595

Published: 2016

Journal Articles

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Virginia Mara De Deus Wagatsuma, PhD, Luisa C A Koury, MD, Silvia Elena Sánchez, MSc, Lorena Lobo Figueiredo Pontes, MD; PhD, Fernanda Borges da Silva, MSc, Adriana Ines Dore, Biologist, Ana Silvia Gouvêa de Lima, PhD, Antonio R. Lucena-Araujo, PhD, Luciana Yamamoto Almeida, PhD, Fabiola Traina, MD, PhD, Felipe Saldanha-Araújo, PhD, Fabio Pittella-Silva, PhD, Eduardo Magalhães Rego, MD, PhD

Blood (2016) 128 (22): 5097.

https://doi.org/10.1182/blood.V128.22.5097.5097

Published: 2016

Journal Articles

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Jarno Kivioja, MSc, Angeliki Thanasopoulou, PhD, Mika Kontro, MD, Bhagwan Yadav, MSc, Muntasir Mamun Majumder, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Kimmo Porkka, MD PhD, Juerg Schwaller, MD, Caroline A Heckman, PhD

Blood (2016) 128 (22): 4711.

https://doi.org/10.1182/blood.V128.22.4711.4711

Published: 2016

Journal Articles

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Sophie Cardin, PhD, Louise Laramee, Tara MacRae, M.Sc., Jalila Chagraoui, PhD, Guy Sauvageau, MD PhD, R. Keith Humphries, MD PhD, Josée Hébert, MD, Brian T. Wilhelm, PhD, Sonia Cellot, MD PhD

Blood (2016) 128 (22): 1535.

https://doi.org/10.1182/blood.V128.22.1535.1535

Published: 2016

Journal Articles

Clinical and Laboratory Studies of 23 Patients with Acute Myeloid Leukemia Harboring t(7; 11) (p15; p15) Translocation

Shuning Wei, Siping Wang, Shaowei Qiu, Junyuan QI, Yingchang Mi, MD PhD, Dong Lin, MDPhD, Chunlin Zhou, MDPhD, Bingcheng Liu, MD, Ying Wang, MD, Min Wang, MD PhD, Jianxiang Wang, MD PhD

Blood (2015) 126 (23): 2519.

https://doi.org/10.1182/blood.V126.23.2519.2519

Published: 2015

Journal Articles

Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative

Blood (2015) 126 (23): 169.

https://doi.org/10.1182/blood.V126.23.169.169

Published: 2015

Journal Articles

NUP98 Fusion Proteins Are Recurrent Aberrancies in Childhood Acute Myeloid Leukemia: A Report from the AIEOP AML-2001-02 Study Group

Valeria Bisio, BS, Martina Pigazzi, PhD, Elena Manara, PhD, Riccardo Masetti, MD, Marco Togni, BS, Annalisa Astolfi, PhD, Cristina Mecucci, MD PhD, Vincenzo Zappavigna, PhD, Valentina Salsi, PhD, Pietro Merli, MD, Carmelo Rizzari, Franca Fagioli, MD, Franco Locatelli, Giuseppe Basso, MD

Blood (2014) 124 (21): 1025.

https://doi.org/10.1182/blood.V124.21.1025.1025

Published: 2014

Journal Articles

Identification of Novel Therapeutic Strategies for NUP98-NSD1-Positive AML By Drug Sensitivity Profiling

Jarno Kivioja, MSc, Mika Kontro, MD, Angeliki Thanasopoulou, PhD, Muntasir Mamun Majumder, MSc,BPharm, Bhagwan Yadav, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Juerg Schwaller, MD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD

Blood (2014) 124 (21): 2160.

https://doi.org/10.1182/blood.V124.21.2160.2160

Published: 2014

Journal Articles

Human NUP98/Iqcg Fusion Gene Induced An Acute Myelomonocytic Leukemia In Mice

Qi-Yao Zhang, Ping Liu, M.D. /Ph.D, Mengmeng Pan, Sai-Juan Chen

Blood (2013) 122 (21): 3725.

https://doi.org/10.1182/blood.V122.21.3725.3725

Published: 2013

Journal Articles

NUP98/NSD1 Translocation Further Risk-Stratifies Patients With FLT3/ITD In Acute Myeloid Leukemia: A Report From Children’s Oncology Group and SWOG

Fabiana Ostronoff, MD, Megan Othus, PhD, Robert B. Gerbing, MA, Michael R. Loken, PhD, Susana C Raimondi, PhD, Betsy A. Hirsch, PhD, Beverly J. Lange, MD, Stephen Petersdorf, MD, Jerald Radich, MD, Frederick R. Appelbaum, MD, Alan S. Gamis, MD, MPH, Todd A. Alonzo, PhD, Soheil Meshinchi, MD, PhD

Blood (2013) 122 (21): 488.

https://doi.org/10.1182/blood.V122.21.488.488

Published: 2013

Journal Articles

NUP98-NSD1 Related Gene Expression Signature Is Strongly Associated with a Poor Prognosis in Pediatric Acute Myeloid Leukemia

Norio Shiba, MD, Hitoshi Ichikawa, PhD, Tomohiko Taki, MD, PhD, Myoung-ja Park, MD, PhD, Aoi Jo, MD, Sachiyo Mitani, BSc, Tohru Kobayashi, MD, PhD, Akira Shimada, MD, PhD, Manabu Sotomatsu, MD, Hirokazu Arakawa, MD, PhD, Souichi Adachi, MD, PhD, Akio Tawa, MD, PhD, Keizo Horibe, MD, Masahiro Tsuchida, MD, PhD, Ryoji Hanada, MD, Ichiro Tsukimoto, MD., PhD, Yasuhide Hayashi, MD, PhD

Blood (2012) 120 (21): 1391.

https://doi.org/10.1182/blood.V120.21.1391.1391

Published: 2012

Journal Articles

Cryptic NUP98/NSD1 Translocations Are Highly Prevalent in FLT3/ITD-Positive Acute Myeloid Leukemia and Lead to High Rate of Induction Failure. Report From Children's Oncology Group

Fabiana Ostronoff, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Michael R. Loken, PhD, Laura Pardo, Richard Aplenc, MD, PhD, Lillian Sung, MD, PhD, Susana C. Raimondi, Betsy A. Hirsch, PhD, Samir Kahwash, MD, Amy Heerema-McKenney, MD, Laura Winter, PharmD, Kathleen Glick, CCRP, Patti Byron, MSN, RN, Robert S. Lavey, MD, Stella M. Davies, MBBS, PhD, Franklin O. Smith, MD, Alan S. Gamis, MD, MPH, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 529.

https://doi.org/10.1182/blood.V120.21.529.529

Published: 2012

Journal Articles

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

Sheryl M. Gough, Christopher I. Slape, Peter D. Aplan

Blood (2011) 118 (24): 6247–6257.

https://doi.org/10.1182/blood-2011-07-328880

Published: 2011

Journal Articles

A NUP98-PHF23 Transgenic Mouse Model Develops AML and T-ALL

Sheryl M Gough, PhD, Fan Lee, BSc, Yang Jo Chung, PhD, Robert L Walker, BSc, Fan Yang, PhD, Yuelin (Jack) Zhu, MD, MSc, Yi Ning, PhD, Paul S Meltzer, MD, PhD, Peter Aplan, MD

Blood (2011) 118 (21): 2467.

https://doi.org/10.1182/blood.V118.21.2467.2467

Published: 2011

Journal Articles

The Nup98-HoxA9 Leukemogenic Fusion Protein Blocks Xpo1 and Tap-Mediated Nuclear Export

Yildirim Dogan, PhD, Sutapa Sahay, PhD, David C Dorn, MD, Anna Franceschino, MD, Michael Xu, Malcolm A.S. Moore, D.Phil

Blood (2011) 118 (21): 5228.

https://doi.org/10.1182/blood.V118.21.5228.5228

Published: 2011

Journal Articles

Loss of p53 Accelerates the Complications of Myelodysplastic Syndromes (MDS) In the NUP98-HOXD13 Transgenic Mouse Model

Haiming Xu, PhD, Silvia Menendez, Tony R Deblasio, Peter Aplan, MD, Stephen Nimer, M.D.

Blood (2011) 118 (21): 2804.

https://doi.org/10.1182/blood.V118.21.2804.2804

Published: 2011

NARROW

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice

HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients

Marked Differences in the Genomic Landscape of Pediatric Compared to Adult Acute Myeloid Leukemia: A Report from the Children's Oncology Group and NCI/COG Therapeutically Applicable Research to Generate Effective Treatments (TARGET) Initiative

Nuclear SET Domain (NSD) Protein Lysine Methyltransferases (KMT) Family Members Expression in Acute Myeloid Leukemia

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells

Clinical and Laboratory Studies of 23 Patients with Acute Myeloid Leukemia Harboring t(7; 11) (p15; p15) Translocation

Rearrangements in Nucleoporin Family of Genes in Childhood Acute Myeloid Leukemia: A Report from Children Oncology Group and NCI/COG Target AML Initiative

NUP98 Fusion Proteins Are Recurrent Aberrancies in Childhood Acute Myeloid Leukemia: A Report from the AIEOP AML-2001-02 Study Group

Identification of Novel Therapeutic Strategies for NUP98-NSD1-Positive AML By Drug Sensitivity Profiling

Human NUP98/Iqcg Fusion Gene Induced An Acute Myelomonocytic Leukemia In Mice

NUP98/NSD1 Translocation Further Risk-Stratifies Patients With FLT3/ITD In Acute Myeloid Leukemia: A Report From Children’s Oncology Group and SWOG

NUP98-NSD1 Related Gene Expression Signature Is Strongly Associated with a Poor Prognosis in Pediatric Acute Myeloid Leukemia

Cryptic NUP98/NSD1 Translocations Are Highly Prevalent in FLT3/ITD-Positive Acute Myeloid Leukemia and Lead to High Rate of Induction Failure. Report From Children's Oncology Group

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

A NUP98-PHF23 Transgenic Mouse Model Develops AML and T-ALL

The Nup98-HoxA9 Leukemogenic Fusion Protein Blocks Xpo1 and Tap-Mediated Nuclear Export

Loss of p53 Accelerates the Complications of Myelodysplastic Syndromes (MDS) In the NUP98-HOXD13 Transgenic Mouse Model

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American Society of Hematology

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American Society of Hematology

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