Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 81

Sort by

Sort Order Select

Journal Articles

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Blood (2020) 136 (5): 553–571.

https://doi.org/10.1182/blood.2019003940

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Transcriptional Regulation of Coenzyme Q Biosynthesis By TIF1γ Drives Erythropoiesis

Marlies P. Rossmann, MD PhD, Karen Hoi, Victoria Chan, Julie R. Perlin, PhD, Elliott J. Hagedorn, PhD, Brian J. Abraham, PhD, Song Yang, PhD, Lucas B. Sullivan, PhD, Curtis R. Warren, PhD, Sejal Vyas, PhD, Eugenia Custo-Creig, Bilguujin Dorjsuren, Chad Cowan, PhD, Marcia C. Haigis, PhD, Richard A. Young, PhD, Leonard I Zon, MD

Blood (2019) 134 (Supplement_1): 152.

https://doi.org/10.1182/blood-2019-126833

Published: 2019

Journal Articles

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death

Frank Cichocki, PhD, Karrune Woan, MD PhD, Cheng-Ying Wu, Bruce R. Blazar, MD, Ryan Bjordahl, PhD, Bahram Valamehr, PhD, Jeffrey S. Miller, MD

Blood (2019) 134 (Supplement_1): 3215.

https://doi.org/10.1182/blood-2019-124490

Published: 2019

Journal Articles

Inhibition of TLR4 Signaling Affects Mitochondrial Fitness Overcoming Bortezomib Resistance in Myeloma Plasma Cells

Cesarina Giallongo, PhD, Daniele Tibullo, PhD, Giuseppina Camiolo, Fabrizio Puglisi, Daniela Cambria, Alessandro Barbato, Nunziatina Laura Parrinello, PhD, Alessandra Romano, MD PhD, Concetta Conticello, MD, Angela Amorini, PhD, Giovanni Li Volti, MD PhD, Giuseppe Lazzarino, Giuseppe A. Palumbo, MD PhD, Francesco Di Raimondo, MD

Blood (2019) 134 (Supplement_1): 3073.

https://doi.org/10.1182/blood-2019-129812

Published: 2019

Journal Articles

Targeting the Plasma Cell Specific Purine Metabolic Enzyme, AMPD1, Induces Multiple Myeloma Cell Death Accompanying NAD Depletion

Yawara Kawano, MD PhD, Takayuki Sasano, Saki Kushima, Yuki Inada, Nao Nishimura, MD, Hiroyuki Hata, MD PhD, Masao Matsuoka, MD PhD

Blood (2019) 134 (Supplement_1): 3097.

https://doi.org/10.1182/blood-2019-125756

Published: 2019

Journal Articles

Targeting Nicotinamide Adenine Dinucleotide (NAD) Glycohydrase Activity of CD38 Exerts Anti-Myeloma Effect Accompanying Intracellular NAD Elevation

Saki Kushima, Takayuki Sasano, Masao Matsuoka, MD PhD, Hiroyuki Hata, MD PhD, Yawara Kawano, MD PhD

Blood (2019) 134 (Supplement_1): 1810.

https://doi.org/10.1182/blood-2019-123624

Published: 2019

Journal Articles

Targeting NMNAT1 in Acute Myeloid Leukemia

Xiangguo Shi, PhD, Daisuke Nakada, PhD, Ayumi Kitano, Rebecca Murdaugh, BS, Yu-Jung Tseng, BS,MS, Kevin Hoegenauer, Tianyuan Hu, PhD, Yajian Jiang, BS

Blood (2019) 134 (Supplement_1): 879.

https://doi.org/10.1182/blood-2019-132139

Published: 2019

Journal Articles

Addition of the PARP Inhibitor, Talazoparib, to Gemtuzumab Ozogamicin Significantly Enhances Anti-Leukemic Activity in Human CD33+ Acute Myeloid Leukemia

Scott M. Portwood, MBA, MS, Marianna C Cantella, BE, Tara L. Cronin, BA, Eunice S. Wang, MD

Blood (2019) 134 (Supplement_1): 1371.

https://doi.org/10.1182/blood-2019-130427

Published: 2019

Journal Articles

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Olukemi Amodu, PhD, Binal N. Shah, Subulade Ademola, PhD, Bamidele Tayo, PhD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 942.

https://doi.org/10.1182/blood-2019-132190

Published: 2019

Journal Articles

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Blood (2019) 134 (Supplement_1): 806.

https://doi.org/10.1182/blood-2019-128930

Published: 2019

Journal Articles

Tryptophan Deprivation Promotes an Adaptive Response and Contributes to Bioenergetics in Multiple Myeloma

Alessandra Romano, MDPhD, Nunziatina Laura Parrinello, Katia Todoerti, PhD, Piera La Cava, Fabrizio Puglisi, Cesarina Giallongo, PhD, Daniele Tibullo, Giuseppina Camiolo, Giuseppe Sapienza, MD, Vittorio Del Fabro, MD, Concetta Conticello, Francesco Piazza, Marilena Carrino, PhD, Giuseppe A. Palumbo, MD, Simone Cenci, MD, Antonino Neri, MD, Francesco Di Raimondo, MD

Blood (2018) 132 (Supplement 1): 4511.

https://doi.org/10.1182/blood-2018-99-116447

Published: 2018

Journal Articles

Targeting NAD + Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure

Phillip J Maciejewski, Yihong Guan, Metis Hasipek, PhD, Anand D. Tiwari, PhD, Dale Grabowski, BS, James G Phillips, PhD, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2018) 132 (Supplement 1): 3840.

https://doi.org/10.1182/blood-2018-99-119300

Published: 2018

Journal Articles

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Blood (2018) 132 (Supplement 1): 4020.

https://doi.org/10.1182/blood-2018-99-117310

Published: 2018

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Saleh Ryan, BSc, Cheryl Peltier, BSc, Mandy Squires, CCRP, HIT, Donna Hewitt, R.N., Paul Fernyhough, PhD, Spencer Bruce Gibson, PhD, Versha Banerji, MD

Blood (2018) 132 (Supplement 1): 1368.

https://doi.org/10.1182/blood-2018-99-112210

Published: 2018

Journal Articles

High Glutathione and NAD(P)H Levels, and Increased Protein Folding Capacity Are Involved in Mediating Proteasome Inhibitor-Resistance in Multiple Myeloma

Lenka Besse, Andrej Besse, Marianne Kraus, Jürgen Bader, Christoph Driessen, MD

Blood (2017) 130 (Supplement 1): 1258.

https://doi.org/10.1182/blood.V130.Suppl_1.1258.1258

Published: 2017

Journal Articles

Use of Next Generation Sequencing Panel to Clarify Undiagnosed Cases of Hereditary Hemolytic Anemias

Elisa Fermo, PhD, Cristina Vercellati, PhD, Anna Paola Marcello, PhD, Ebru Yilmaz Keskin, MD, Aurora Feliu Torres, MD, Silverio Perrotta, Tekin Aksu, MD, Anna Zaninoni, BS, Valentina Brancaleoni, MSc, Richard van Wijk, PhD, Sultan Aydin Koker, MD, Alberto Zanella, MD, Agostino Cortelezzi, Prof, Wilma Barcellini, MD, Paola Bianchi, BSc, PhD

Blood (2017) 130 (Supplement 1): 3480.

https://doi.org/10.1182/blood.V130.Suppl_1.3480.3480

Published: 2017

Journal Articles

Enhanced In Vivo Persistence and Proliferation of NK Cells Expanded in Culture with the Small Molecule Nicotinamide: Development of a Clinical-Applicable Method for NK Expansion

Tony Peled, Guy Brachya, Nurit Persi, Chana Lador, Esti Olesinski, Efrat Landau, Einat Galamidi, Amnon Peled, Jeffrey S. Miller, MD, Veronika Bachanova, MD PhD

Blood (2017) 130 (Supplement 1): 657.

https://doi.org/10.1182/blood.V130.Suppl_1.657.657

Published: 2017

Journal Articles

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Kristy Stengel, PhD, Srividya Bhaskara, PhD, Jing Wang, PhD, Qi Liu, PhD, Scott Hiebert, PhD

Blood (2017) 130 (Supplement 1): 311.

https://doi.org/10.1182/blood.V130.Suppl_1.311.311

Published: 2017

Journal Articles

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Alessandra Romano, MDPhD, Laura Oliva, PhD, Jose Manuel Manteiga, Todoerti Katia, Lorenzo Canziani, Matteo Trudu, Francesca Fontana, Michela Ghizzinardi, Ugo Orfanelli, Magda Marcatti, MD, Fabio Ciceri, MD, Giovanni Tonon, MD PhD, Antonino Neri, MD, Claudio Cerichione, MD PhD, Francesco Di Raimondo, MD, Simone Cenci, MD

Blood (2017) 130 (Supplement 1): 3051.

https://doi.org/10.1182/blood.V130.Suppl_1.3051.3051

Published: 2017

NARROW

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

Transcriptional Regulation of Coenzyme Q Biosynthesis By TIF1γ Drives Erythropoiesis

NK Cells Lacking CD38 Are Resistant to Oxidative Stress-Induced Death

Inhibition of TLR4 Signaling Affects Mitochondrial Fitness Overcoming Bortezomib Resistance in Myeloma Plasma Cells

Targeting the Plasma Cell Specific Purine Metabolic Enzyme, AMPD1, Induces Multiple Myeloma Cell Death Accompanying NAD Depletion

Targeting Nicotinamide Adenine Dinucleotide (NAD) Glycohydrase Activity of CD38 Exerts Anti-Myeloma Effect Accompanying Intracellular NAD Elevation

Targeting NMNAT1 in Acute Myeloid Leukemia

Addition of the PARP Inhibitor, Talazoparib, to Gemtuzumab Ozogamicin Significantly Enhances Anti-Leukemic Activity in Human CD33+ Acute Myeloid Leukemia

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Tryptophan Deprivation Promotes an Adaptive Response and Contributes to Bioenergetics in Multiple Myeloma

Targeting NAD + Modulating Enzymes to Improve HSC Function in Aging and Bone Marrow Failure

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

High Glutathione and NAD(P)H Levels, and Increased Protein Folding Capacity Are Involved in Mediating Proteasome Inhibitor-Resistance in Multiple Myeloma

Use of Next Generation Sequencing Panel to Clarify Undiagnosed Cases of Hereditary Hemolytic Anemias

Enhanced In Vivo Persistence and Proliferation of NK Cells Expanded in Culture with the Small Molecule Nicotinamide: Development of a Clinical-Applicable Method for NK Expansion

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Arginine Deprivation and Autophagy Sustain Bioenergetics in Multiple Myeloma

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only