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Journal Articles

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Naoya Uchida, MD, Linhong Li, PhD, Tina Nassehi, Morgan Yapundich, Jackson Gamer, Claire Drysdale, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Cornell Allen, MS, Suk See De Ravin, MD, PhD, Robert E. Donahue, VMD, Harry L. Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 609.

https://doi.org/10.1182/blood-2019-122727

Published: 2019

Journal Articles

A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates

Blood (2019) 134 (Supplement_1): 610.

https://doi.org/10.1182/blood-2019-125968

Published: 2019

Journal Articles

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Naoya Uchida, MD, Claire Drysdale, Morgan Yapundich, Jackson Gamer, Tina Nassehi, Matthew Wielgosz, Francesca Ferrara, PhD, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Byoung Y. Ryu, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 2063.

https://doi.org/10.1182/blood-2019-122770

Published: 2019

Journal Articles

Evaluation of the Human Factor IX Gene Therapy Vector TAK-748 in Hemophilia: Results from Non-Clinical Studies in Factor IX Knockout Mice and Rhesus Monkeys

Markus Weiller, Helen Wang, Sogué Coulibaly, Maria Schuster, Hanspeter Rottensteiner, Kefeng Sun, Marinee K Chuah, Thierry Vandendriessche, Friedrich Scheiflinger, Werner Höllriegl

Blood (2019) 134 (Supplement_1): 4633.

https://doi.org/10.1182/blood-2019-124734

Published: 2019

Journal Articles

Is There a Role for Titre Monitoring in Kell Alloimmunized Pregnancies?

Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, Maciej W Garbowski, MD PhD, Gareth Seaward, MD, Rory Windrim, MD, Johannes Keunen, Edmond Kelly, MB, BCh, BAO, DCH, FRCPC, FAAP, Tim VanMieghem, MD PhD, Nadine Shehata, MDFRCPC,MSc, Greg Ryan, MD

Blood (2019) 134 (Supplement_1): 1174.

https://doi.org/10.1182/blood-2019-125144

Published: 2019

Journal Articles

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Kristopher D Marjon, PhD, James Y Chen, MD PhD, Jiaqi Duan, MS, Timothy S Choi, BS, Kavitha Sompalli, MS, Dongdong Feng, PhD, Ofelia Mata, Sharline Chen, B.S., Leslie Kean, MD PhD, Mwe Mwe Chao, MD, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Cynthia E. Dunbar, MD, Ravi Majeti, MD PhD, Irving L Weissman, MD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2019) 134 (Supplement_1): 4428.

https://doi.org/10.1182/blood-2019-131490

Published: 2019

Journal Articles

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Blood (2019) 134 (Supplement_1): 4632.

https://doi.org/10.1182/blood-2019-129394

Published: 2019

Journal Articles

Red Blood Cell Allo-Antibodies after Allogeneic Hematopoietic Stem Cell Transplantation

Astrid Beerlage, MD, Joerg Halter, MD, Sabine Gerull, MD, Michael Medinger, MD, Tanja Ruefli, Georg Stussi, MD, Dominik Heim, MD, Beatrice Drexler, MD, Laura Infanti, MD, Andreas Holbro, MD, Jakob R. Passweg, MDMS, Andreas S. Buser, MD

Blood (2018) 132 (Supplement 1): 2551.

https://doi.org/10.1182/blood-2018-99-116237

Published: 2018

Journal Articles

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

Hillard M Lazarus, MD, Leland Metheny, MD, Tsila Zuckerman, MD, Carolina Escobar, MD, Joseph P. McGuirk, DO, Yael Rosen, MD, Jacob M. Rowe, MD

Blood (2018) 132 (Supplement 1): 3379.

https://doi.org/10.1182/blood-2018-99-116239

Published: 2018

Journal Articles

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

Sanggu Kim, PhD, Robert E. Donahue, VMD, Aylin Bonifacino, MS, Mark Metzger, Cynthia E. Dunbar, MD, Irvin Chen, PhD

Blood (2018) 132 (Supplement 1): 4524.

https://doi.org/10.1182/blood-2018-99-117047

Published: 2018

Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2018) 132 (Supplement 1): 1418.

https://doi.org/10.1182/blood-2018-99-118572

Published: 2018

Journal Articles

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Taehoon Shin, PhD, Eun Jung Baek, MD, Marcus A.F. Corat, PhD, Shirley Chen, BS, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2018-99-111984

Published: 2018

Journal Articles

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Blood (2018) 132 (Supplement 1): 5677.

https://doi.org/10.1182/blood-2018-99-114730

Published: 2018

Journal Articles

Preclinical Evaluation of an Engineered AAV Capsid in Non-Human Primates for the Treatment of Haemophilia B

Allison Dane, PhD, Jenny McIntosh, Doyoung Lee, PhD, Rose Sheridan, Mark Maginn, Romuald Corbau, PhD, Andrew M. Davidoff, MD, Amit C Nathwani, MD PhD

Blood (2018) 132 (Supplement 1): 2197.

https://doi.org/10.1182/blood-2018-99-117969

Published: 2018

Journal Articles

Persistence of CRISPR/Cas9-Edited Hematopoietic Stem and Progenitor Cells and Reactivation of Fetal Hemoglobin in Nonhuman Primates

Olivier Humbert, PhD, Stefan Radtke, PhD, Ray R Carillo, Anai M Perez, Sowmya Somashekar Reddy, Lauren E Schefter, Christopher Lux, MDPhD, Sowmya Pattabhi, PhD, Olivier Negre, PhD, Ciaran M Lee, PhD, Jennifer Adair, PhD, Christopher Peterson, PhD, Gang Bao, PhD, David J. Rawlings, MD, Andrew M. Scharenberg, MD, Hans-Peter Kiem, MD PhD

Blood (2018) 132 (Supplement 1): 806.

https://doi.org/10.1182/blood-2018-99-112996

Published: 2018

Journal Articles

Rhesus pieces: genotype matching of RBCs

Jeanne E. Hendrickson, Christopher A. Tormey

Blood (2018) 132 (11): 1091–1093.

https://doi.org/10.1182/blood-2018-07-865634

Published: 2018

Journal Articles

Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques

Anandani Nellan, Cynthia M. Lester McCully, Rafael Cruz Garcia, Nalini Jayaprakash, Brigitte C. Widemann, Daniel W. Lee, Katherine E. Warren

Blood (2018) 132 (6): 662–666.

https://doi.org/10.1182/blood-2018-05-846428

Published: 2018

Journal Articles

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Xing Fan, MD, Chuanfeng Wu, MD, Diego Espinoza, Stephanie Sellers, Aylin Bonifacino, MS, Robert E Donahue, VMD, Luca Schifanella, Genoveffa Franchini, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 932.

https://doi.org/10.1182/blood.V130.Suppl_1.932.932

Published: 2017

Journal Articles

Modeling and Understanding the Biology of Transplant-Mediated HIV Cure in a Non-Human Primate Model

Blood (2017) 130 (Supplement 1): 694.

https://doi.org/10.1182/blood.V130.Suppl_1.694.694

Published: 2017

Journal Articles

Skewed HSC Clonal Output of T-Cells in an Aged Rhesus Macaque after CD3e-Immunotoxin Treatment

Sanggu Kim, PhD, Gajendra Suryavanshi, PhD, Aylin Bonifacino, MS, Chuanfeng Wu, MD, Cynthia E Dunbar, MD, Robert E Donahue, VMD, Irvin Chen, PhD

Blood (2017) 130 (Supplement 1): 3758.

https://doi.org/10.1182/blood.V130.Suppl_1.3758.3758

Published: 2017

NARROW

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

A Single Dose of CD117 Antibody Drug Conjugate Enables Autologous Gene-Modified Hematopoietic Stem Cell Transplant (Gene Therapy) in Nonhuman Primates

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Evaluation of the Human Factor IX Gene Therapy Vector TAK-748 in Hemophilia: Results from Non-Clinical Studies in Factor IX Knockout Mice and Rhesus Monkeys

Is There a Role for Titre Monitoring in Kell Alloimmunized Pregnancies?

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Red Blood Cell Allo-Antibodies after Allogeneic Hematopoietic Stem Cell Transplantation

Prospective, Multi-Center, Phase I Clinical Trial of PLX-R18 Placental Expanded Adherent Stromal Cells in Subjects with Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation

Preclinical Evaluation of an Engineered AAV Capsid in Non-Human Primates for the Treatment of Haemophilia B

Persistence of CRISPR/Cas9-Edited Hematopoietic Stem and Progenitor Cells and Reactivation of Fetal Hemoglobin in Nonhuman Primates

Rhesus pieces: genotype matching of RBCs

Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Modeling and Understanding the Biology of Transplant-Mediated HIV Cure in a Non-Human Primate Model

Skewed HSC Clonal Output of T-Cells in an Aged Rhesus Macaque after CD3e-Immunotoxin Treatment

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American Society of Hematology

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ASH Publications

American Society of Hematology

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