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Journal Articles

Evaluation of the Human Factor IX Gene Therapy Vector TAK-748 in Hemophilia: Results from Non-Clinical Studies in Factor IX Knockout Mice and Rhesus Monkeys

Markus Weiller, Helen Wang, Sogué Coulibaly, Maria Schuster, Hanspeter Rottensteiner, Kefeng Sun, Marinee K Chuah, Thierry Vandendriessche, Friedrich Scheiflinger, Werner Höllriegl

Blood (2019) 134 (Supplement_1): 4633.

https://doi.org/10.1182/blood-2019-124734

Published: 2019

Journal Articles

Lethality of Mouse Tissue Factor Pathway Inhibitor Gene Disruption Is Rescued By Transgenic Human Tissue Factor Pathway Inhibitor Knock in

Robert Pachlinger, Rudolf Hartmann, Andrea Kolm, Erwin Panholzer, Nadja Ullrich, Fabian Knofl, Maria Schuster, Werner Hoellriegl, DVM, Friedrich Scheiflinger, PhD, Michael Dockal

Blood (2015) 126 (23): 3495.

https://doi.org/10.1182/blood.V126.23.3495.3495

Published: 2015

Journal Articles

CD4 + T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

Katharina N. Steinitz, Pauline M. van Helden, Brigitte Binder, David C. Wraith, Sabine Unterthurner, Corinna Hermann, Maria Schuster, Rafi U. Ahmad, Markus Weiller, Christian Lubich, Maurus de la Rosa, Hans Peter Schwarz, Birgit M. Reipert

Blood (2012) 119 (17): 4073–4082.

https://doi.org/10.1182/blood-2011-08-374645

Published: 2012

Includes: Supplemental data

Journal Articles

Preclinical Immunogenicity Assessment of Baxter‘s Recombinant Factor VIIa,

Frank M Horling, PhD, Christine Lenk, Rafi Uddin Ahmad, PhD, Markus Weiller, PhD, Maria Schuster, DVM, Hans Peter Schwarz, MD, Birgit M Reipert, PhD

Blood (2011) 118 (21): 3327.

https://doi.org/10.1182/blood.V118.21.3327.3327

Published: 2011

Journal Articles

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

Pauline M. van Helden, Sabine Unterthurner, Corinna Hermann, Maria Schuster, Rafi U. Ahmad, Alexandra N. Schiviz, Markus Weiller, Gerhard Antoine, Peter L. Turecek, Eva M. Muchitsch, Hans Peter Schwarz, Birgit M. Reipert

Blood (2011) 118 (13): 3698–3707.

https://doi.org/10.1182/blood-2010-11-316521

Published: 2011

Journal Articles

Immune Tolerance to Human Factor VIII Induced by Liver-Specific Expression of a Human Factor VIII Transgene in Hemophilic Mice.

Pauline van Helden, PhD, Maria Sasgary, PhD, Sabine Unterthurner, Mag, Maria Schuster, PhD, Gerhard Antoine, PhD, Klaus Zimmermann, PhD, Rafi Uddin Ahmad, PhD, Eva M Muchitsch, PhD, Hartmut J Ehrlich, MD, Hans Peter Schwarz, MD, Birgit M Reipert, PhD

Blood (2008) 112 (11): 3387.

https://doi.org/10.1182/blood.V112.11.3387.3387

Published: 2008

Journal Articles

Humanized E17 Hemophilic Mice Are a Major Breakthrough in the Design of New Preclinical Models for Developing Factor VIII Products with Reduced Immunogenicity.

Birgit M. Reipert, PhD, Christina Hausl, PhD, Maria Sasgary, PhD, Maria Schuster, Rafi U. Ahmad, PhD, Bernhard Baumgartner, PhD, Josenato Ilas, Natalie Bauer, Hartmut Ehrlich, MD, Hans Peter Schwarz, MD

Blood (2007) 110 (11): 782.

https://doi.org/10.1182/blood.V110.11.782.782

Published: 2007

NARROW

Evaluation of the Human Factor IX Gene Therapy Vector TAK-748 in Hemophilia: Results from Non-Clinical Studies in Factor IX Knockout Mice and Rhesus Monkeys

Lethality of Mouse Tissue Factor Pathway Inhibitor Gene Disruption Is Rescued By Transgenic Human Tissue Factor Pathway Inhibitor Knock in

CD4 + T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

Preclinical Immunogenicity Assessment of Baxter‘s Recombinant Factor VIIa,

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

Immune Tolerance to Human Factor VIII Induced by Liver-Specific Expression of a Human Factor VIII Transgene in Hemophilic Mice.

Humanized E17 Hemophilic Mice Are a Major Breakthrough in the Design of New Preclinical Models for Developing Factor VIII Products with Reduced Immunogenicity.

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ASH Publications

American Society of Hematology

Evaluation of the Human Factor IX Gene Therapy Vector TAK-748 in Hemophilia: Results from Non-Clinical Studies in Factor IX Knockout Mice and Rhesus Monkeys

Lethality of Mouse Tissue Factor Pathway Inhibitor Gene Disruption Is Rescued By Transgenic Human Tissue Factor Pathway Inhibitor Knock in

CD4 + T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

Preclinical Immunogenicity Assessment of Baxter‘s Recombinant Factor VIIa,

Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model

Immune Tolerance to Human Factor VIII Induced by Liver-Specific Expression of a Human Factor VIII Transgene in Hemophilic Mice.

Humanized E17 Hemophilic Mice Are a Major Breakthrough in the Design of New Preclinical Models for Developing Factor VIII Products with Reduced Immunogenicity.

Email alerts

ASH Publications

American Society of Hematology

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