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Journal Articles

Combination of Gatekeeper Mutations and Cysteine 481 Replacement Causes Super Resistance to the Irreversible BTK Inhibitors Ibrutinib, Acalabrutinib and Zanubrutinib

Hernando Yesid Estupiñan Velasquez, Yuye Shi, MD PhD, Dara K. Mohammad, PhD, Qing Wang, Mauno Vihinen, PhD, Rula Zain, PhD, Anna Berglöf, PhD VMD, Edvard CI Smith, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5759.
https://doi.org/10.1182/blood-2019-123398
Published: 2019
Journal Articles

Generation of a Lenalidomide-Sensitive Mouse Model for Multiple Myeloma By Expression of the Crbn I391V Mutant in Mopc-315.BM Cells

Dilan Serdar, Simon Köpff, Annika Scheffold, Jan Kronke
Journal: Blood
Blood (2017) 130 (Supplement 1): 3071.
https://doi.org/10.1182/blood.V130.Suppl_1.3071.3071
Published: 2017
Journal Articles

TCIRG1 Mutations As a Cause for Chronic Neutropenia

Vahagn Makaryan, MD, Breanna Fletcher, BSc, Merideth L. Kelley, MS, Audrey Anna Bolyard, RN, BS, Daniel C. Link, MD, Eric J. Duncavage, MD, David Augustus Qualls, MD, David C. Dale, MD
Journal: Blood
Blood (2016) 128 (22): 2511.
https://doi.org/10.1182/blood.V128.22.2511.2511
Published: 2016
Journal Articles

A Meta-Analysis and Meta-Regression of the Efficacy of Front-Line Treatment Combinations with Ponatinib Versus 1st- and 2nd-Generation Tyrosine Kinase Inhibitors for Ph+ Acute Lymphoblastic Leukemia

Elias J. Jabbour, MD, Maral DerSarkissian, PhD, Mei Sheng Duh, Nora McCormick, MSc, Wendy Y. Cheng, MPH, MPhil, Lisa J. McGarry, MPH, Ariadne Souroutzidis, BA, Hui Huang, PhD MBA, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2016) 128 (22): 5189.
https://doi.org/10.1182/blood.V128.22.5189.5189
Published: 2016
Journal Articles

Alu-Element Insertion in Pklr Gene As a Novel Cause of Severe Hereditary Nonspherocytic Hemolytic Anemia

Harry Lesmana, MD, Lisa Dyer, PhD, Ping Zhou, Xia Li, PhD, James Denton, MS, Satheesh Chonat, MD, Kejian Zhang, MD MBA, Robert J. Hopkin, MD, Theodosia A. Kalfa, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3349.
https://doi.org/10.1182/blood.V126.23.3349.3349
Published: 2015
Journal Articles

A Nationwide Observational Study of the Israeli Experience with Ponatinib Outside Clinical Trials in Chronic Myeloid Leukemia

Adi Shacham Abulafia, MD, Pia Raanani, MD, David Lavie, MD, Yulia Volchek, MD, Ron Ram, MD, Ilana Hellmann, MD, Liat Shargian, MD, Anna Gourevietch, MD, Evgeni Chubar, MD, Roy Ratzon, BSC, Uri Rozovski, MD
Journal: Blood
Blood (2015) 126 (23): 5155.
https://doi.org/10.1182/blood.V126.23.5155.5155
Published: 2015
Journal Articles

Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells

Polina Matre, PhD, Marina Protopopova, Ningping Feng, Jason Gay, Jennifer Greer, Juliana Velez, Hong Mu, MD PhD, Alessia Lodi, Surendar Tadi, Shannon Sweeney, Michael Andreeff, MD PhD, Stefano Tiziani, M. Emilia DiFrancesco, Joseph Marszalek, Marina Konopleva, MD PhD
Journal: Blood
Blood (2014) 124 (21): 622.
https://doi.org/10.1182/blood.V124.21.622.622
Published: 2014
Journal Articles

A Zymogen-like Factor Xa Improves Hemostasis in a Murine Bleeding Model

Jasuja Reema, PhD, Sunita Patel-Hett, PhD, Rodney M. Camire, PhD, Joachim Fruebis, PhD, Debra Pittman
Journal: Blood
Blood (2014) 124 (21): 1476.
https://doi.org/10.1182/blood.V124.21.1476.1476
Published: 2014
Journal Articles

Specific Leucine, Isoleucine and Threonine Residues In The TFPIα C-Terminal Region Are Necessary For Inhibition Of Prothrombinase

Jeremy P Wood, PhD, Alan E. Mast, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3562.
https://doi.org/10.1182/blood.V122.21.3562.3562
Published: 2013
Journal Articles

Mutations In UBA3 Confer Resistance To The NEDD8-Activating Enzyme Inhibitor MLN4924 In Human Leukemic Cells

G. Wei Xu, MD, PhD, Julia I. Toth, PhD, Sara R. da Silva, BSc, Stacey-Lynn Paiva, BSc, Julie L. Lukkarila, PhD, Rose Hurren, Neil Maclean, BSc, Mahadeo A. Sukhai, PhD, Rabindra N. Bhattacharjee, PhD, Carolyn A. Goard, PhD, Bruno C Medeiros, MD, Patrick T. Gunning, PhD, Sirano Dhe-Paganon, PhD, Matthew D. Petroski, PhD, Aaron Schimmer, PhD, MD
Journal: Blood
Blood (2013) 122 (21): 2527.
https://doi.org/10.1182/blood.V122.21.2527.2527
Published: 2013
Journal Articles

KIR3DL1 and HLA-Bw4 Allotypes Predict The Extent Of NK Cell Licensing

Jeanette E Boudreau, BSc, PhD, Jean-Benoit Le Luduec, BSc, MSc, PhD, Katharine C. Hsu, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1043.
https://doi.org/10.1182/blood.V122.21.1043.1043
Published: 2013
Journal Articles

Functional Enrichment Analysis by David in Transgenic MYCN Zebrafish Model

Li-Jing Shen, Fang-Yuan Chen, Lan-Fang Cao, Yong Zhang, Hua Zhong
Journal: Blood
Blood (2012) 120 (21): 5114.
https://doi.org/10.1182/blood.V120.21.5114.5114
Published: 2012
Journal Articles

Analysis of in Vitro Activity of the Clinically-Active ABL/FLT3 Inhibitor Ponatinib (AP24534) Against AC220-Resistant FLT3-ITD Mutants

Catherine C. Smith, MD, Lauren E. Damon, Xiaotian Zhu, PhD, Sara Salerno, BS, Neil Shah, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 930.
https://doi.org/10.1182/blood.V118.21.930.930
Published: 2011
Journal Articles

Functional Characterization of a Recombinant FVIIa Drug Candidate

Peter L Turecek, PhD, Katalin Varadi, PhD, Susanne Vejda, PhD, Ernst Boehm, PhD, Hanspeter Rottensteiner, PhD, Hans Peter Schwarz, PhD, Artur Mitterer, PhD, Wolfgang Mundt, PhD, Hartmut J. Ehrlich, MD, Friedrich Scheiflinger, PhD
Journal: Blood
Blood (2010) 116 (21): 4653.
https://doi.org/10.1182/blood.V116.21.4653.4653
Published: 2010
Journal Articles

Single Base Pair Mutation Detection by PNA Direct PCR Clamping: Application to Bcr-Abl T315I Mutation

Enrico Bracco, PhD, Roberto Pedrola, Marco Lo Iacono, Francesca Arruga, PhD, Valentina Rosso, Erika Deklic, Stefano Mussino, PhD, Sonia Carturan, PhD, Francesca Messa, PhD, Ilaria Defilippi, PhD, Cristina Panuzzo, PhD, Paolo Nicoli, MD, Emanuela Messa, MD, Antonia Rotolo, Alessandro Morotti, MD, Alessandra Balbo, PhD, Margherita Valente, Roberto Sapio, Daniela Cilloni, Giuseppe Saglio, MD
Journal: Blood
Blood (2008) 112 (11): 4224.
https://doi.org/10.1182/blood.V112.11.4224.4224
Published: 2008
Journal Articles

Activity of the Multi-Targeted Kinase Inhibitor, AT9283 on Imatinib-Resistant CML Models.

Ruriko Tanaka, MMSc, Matthew S Squires, PhD, Shinya Kimura, MD, PhD, Asumi Yokota, MMSc, Kirsty Mallett, PhD, Tomoko Smyth, PhD, Neil T Thompson, PhD, Rina Nagao, Takahiro Yamauchi, MD, Takashi Ushiki, MD, John F Lyons, PhD, Taira Maekawa, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1104.
https://doi.org/10.1182/blood.V112.11.1104.1104
Published: 2008
Journal Articles

Transfusion Independence Achieved in a Case of Diamond Blackfan Anaemia by Essential Amino Acid Supplementation

Diana Wright, Sarah Ball, Josu de la Fuente
Journal: Blood
Blood (2008) 112 (11): 4119.
https://doi.org/10.1182/blood.V112.11.4119.4119
Published: 2008
Journal Articles

Intermediaries of Branched-Chain Amino Acid Metabolism Can Increase Fetal Hemoglobin In Vitro and In Vivo .

Himanshu Bhatia, MD, Jaimie Higgs, BA, Sonja Hess, PhD, Cynthia Tifft, MD, PhD, Jane Little, MD
Journal: Blood
Blood (2007) 110 (11): 3834.
https://doi.org/10.1182/blood.V110.11.3834.3834
Published: 2007
Journal Articles

C1GALT1C1 ( COSMC ) Mutations in Four Individuals with Tn+ Phenotype.

Vanja Karamatic Crew, PhD, Carole Green, FIBMS, Stephen Parsons, PhD, Belinda K. Singleton, PhD, Geoff Daniels, PhD, David J. Anstee, PhD
Journal: Blood
Blood (2007) 110 (11): 1727.
https://doi.org/10.1182/blood.V110.11.1727.1727
Published: 2007
Journal Articles

Polymorphisms in the MGMT Gene as Predictors of Leukemia Risk and Response to Therapy in Children with AML.

Alex George, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, MS, Soheil Meshinchi, MD, Julie A. Ross, PhD, John P. Perentesis, MD, Stella M. Davies, MD PhD
Journal: Blood
Blood (2007) 110 (11): 1444.
https://doi.org/10.1182/blood.V110.11.1444.1444
Published: 2007