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Journal Articles

Candidemia-Induced Emergency Granulopoiesis Consists of Successive Dual Waves Triggered by the Shift From C/EBPalpha to C/EBPbeta Dependency.

Sakiko Satake, MD, Hideyo Hirai, MD, PhD, Nobuaki Shime, MD, PhD, Rina Nagao, Ruriko Tanaka, MMSc, Hisayuki Yao, MD, Yoshihiro Hayashi, MD, Eishi Ashihara, MD, PhD, Tohru Inaba, MD, PhD, Naohisa Fujita, MD, PhD, Jiro Imanishi, MD, PhD, Taira Maekawa, MD, DMSci

Blood (2010) 116 (21): 3778.

https://doi.org/10.1182/blood.V116.21.3778.3778

Published: 2010

Journal Articles

Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL–positive leukemic cells

Ruriko Tanaka, Matthew S. Squires, Shinya Kimura, Asumi Yokota, Rina Nagao, Takahiro Yamauchi, Miki Takeuchi, Hisayuki Yao, Matthias Reule, Tomoko Smyth, John F. Lyons, Neil T. Thompson, Eishi Ashihara, Oliver G. Ottmann, Taira Maekawa

Blood (2010) 116 (12): 2089–2095.

https://doi.org/10.1182/blood-2009-03-211466

Published: 2010

Includes: Supplemental data

Journal Articles

Hypoxia-Adapted CML Cells Are More Primitive Population and Are Eradicated by Glyoxalase-1 Inhibitors.

Miki Takeuchi, MD, Shinya Kimura, MD, PhD, Junya Kuroda, MD, PhD, Eishi Ashihara, MD, PhD, Makoto Kawatani, PhD, Hiroyuki Osada, PhD, Kazuo Umezawa, PhD, Eiko Yasui, PhD, Masaya Imoto, PhD, Takashi Tsuruo, MD, PhD, Asumi Yokota, MMSc, Ruriko Tanaka, MMSc, Rina Nagao, Tatsutoshi Nakahata, M.D., Ph.D., Yoshihide Fujiyama, MD, PhD, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 2166.

https://doi.org/10.1182/blood.V114.22.2166.2166

Published: 2009

Journal Articles

Inhibition of Wnt/β-Catenin Signaling by AV65 Treatment Caused Cell Cycle Arrest and Induced Caspase-Independent or -Dependent Apoptosis in CML Cells.

Rina Nagao, Eishi Ashihara, MD, PhD, Shinya Kimura, MD, PhD, Hisayuki Yao, MD, Miki Takeuchi, MD, Asumi Yokota, MMSc, Ruriko Tanaka, MMSc, Hideyo Hirai, MD, PhD, Jeffrey W Strovel, Janak Padia, Wieslaw M Cholody, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 2184.

https://doi.org/10.1182/blood.V114.22.2184.2184

Published: 2009

Journal Articles

Automated and Rapid Detection of BCR-ABL Kinase Domain Mutations in IM Resistant Patients with Ph+ Leukemias.

Ruriko Tanaka, MMSc, Shinya Kimura, MD, PhD, Toshiya Hosomi, Mitsuharu Hirai, Rina Nagao, Asumi Yokota, MMSc, Yuri Kamitsuji, MD, PhD, Eri Kawata, MD, PhD, Hisayuki Yao, MD, Kazuki Sakai, MD, Hideyo Hirai, MD, PhD, Eishi Ashihara, MD, PhD, Souichi Adachi, MD, PhD, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 2590.

https://doi.org/10.1182/blood.V114.22.2590.2590

Published: 2009

Journal Articles

AV-65, a Novel Inhibitor of the Wnt/β-Catenin Signaling Pathway, Inhibits the Proliferation of Myeloma Cells.

Hisayuki Yao, MD, Eishi Ashihara, MD, PhD, Rina Nagao, Shinya Kimura, MD, PhD, Hideyo Hirai, MD, PhD, Jeffrey W Strovel, PhD, Janak Padia, PhD, Wieslaw M Cholody, PhD, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 2866.

https://doi.org/10.1182/blood.V114.22.2866.2866

Published: 2009

Journal Articles

Osteoclasts Are Involved in the Maintenance of Dormant Leukemic Cells.

Asumi Yokota, MMSc, Shinya Kimura, MD, PhD, Ruriko Tanaka, MMSc, Miki Takeuchi, MD, Hisayuki Yao, MD, Kazuki Sakai, MD, Rina Nagao, Eishi Ashihara, MD, PhD, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 4245.

https://doi.org/10.1182/blood.V114.22.4245.4245

Published: 2009

Journal Articles

Roles of Osteoclasts in Leukemic Cells

Asumi Yokota, MMSc, Shinya Kimura, MD, PhD, Ruriko Tanaka, MMSc, Rina Nagao, Kazuki Sakai, MD, Hisayuki Yao, MD, Miki Takeuchi, MD, Makoto Kawatani, PhD, Hiroyuki Osada, PhD, Eishi Ashihara, MD, PhD, Taira Maekawa, MD, PhD

Blood (2008) 112 (11): 3184.

https://doi.org/10.1182/blood.V112.11.3184.3184

Published: 2008

Journal Articles

A Novel β-catenin Inhibitor, AV65 Suppresses the Growth of CML Cell Lines Which Acquire Imatinib-Resistance Because of Abl Kinase Domain Mutations Including T315I and Hypoxia-Adaptation.

Rina Nagao, Shinya Kimura, MD, PhD, Eishi Ashihara, MD, PhD, Miki Takeuchi, MD, Ruriko Tanaka, MMSc, Asumi Yokota, MMSc, Hisayuki Yao, MD, Jeffrey W Strovel, Wieslaw M Cholody, Taira Maekawa, MD, PhD

Blood (2008) 112 (11): 1081.

https://doi.org/10.1182/blood.V112.11.1081.1081

Published: 2008

Journal Articles

Activity of the Multi-Targeted Kinase Inhibitor, AT9283 on Imatinib-Resistant CML Models.

Ruriko Tanaka, MMSc, Matthew S Squires, PhD, Shinya Kimura, MD, PhD, Asumi Yokota, MMSc, Kirsty Mallett, PhD, Tomoko Smyth, PhD, Neil T Thompson, PhD, Rina Nagao, Takahiro Yamauchi, MD, Takashi Ushiki, MD, John F Lyons, PhD, Taira Maekawa, MD, PhD

Blood (2008) 112 (11): 1104.

https://doi.org/10.1182/blood.V112.11.1104.1104

Published: 2008

NARROW

Candidemia-Induced Emergency Granulopoiesis Consists of Successive Dual Waves Triggered by the Shift From C/EBPalpha to C/EBPbeta Dependency.

Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL–positive leukemic cells

Hypoxia-Adapted CML Cells Are More Primitive Population and Are Eradicated by Glyoxalase-1 Inhibitors.

Inhibition of Wnt/β-Catenin Signaling by AV65 Treatment Caused Cell Cycle Arrest and Induced Caspase-Independent or -Dependent Apoptosis in CML Cells.

Automated and Rapid Detection of BCR-ABL Kinase Domain Mutations in IM Resistant Patients with Ph+ Leukemias.

AV-65, a Novel Inhibitor of the Wnt/β-Catenin Signaling Pathway, Inhibits the Proliferation of Myeloma Cells.

Osteoclasts Are Involved in the Maintenance of Dormant Leukemic Cells.

Roles of Osteoclasts in Leukemic Cells

A Novel β-catenin Inhibitor, AV65 Suppresses the Growth of CML Cell Lines Which Acquire Imatinib-Resistance Because of Abl Kinase Domain Mutations Including T315I and Hypoxia-Adaptation.

Activity of the Multi-Targeted Kinase Inhibitor, AT9283 on Imatinib-Resistant CML Models.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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