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Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Blood (2020) 135 (1): 28–40.

https://doi.org/10.1182/blood.2019000032

Published: 2020

Includes: Supplemental data

Journal Articles

A Multi-Center Dose-Finding Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Fimepinostat (CUDC-907) in Combination with Venetoclax in Patients with Relapsed/Refractory (R/R) Lymphoma

Anas Younes, MD, Connie Lee Batlevi, MD PhD, Jonathon B. Cohen, MDMS, Sven de Vos, MD PhD, Daniel J. Landsburg, MD, Zaw Win Myint, MD, Krish Patel, MD, Tycel J. Phillips, MD, Sonali M. Smith, MD, Jason R. Westin, MD, Anna W Ma, MS, Dena Grayson, MD PhD, Reinhard von Roemeling, MD, Stefan K. Barta, MD MRCP, MS

Blood (2019) 134 (Supplement_1): 4104.

https://doi.org/10.1182/blood-2019-128857

Published: 2019

Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2019) 134 (Supplement_1): 3972.

https://doi.org/10.1182/blood-2019-121847

Published: 2019

Journal Articles

The Ire of IRE1α: Overexpression of IRE1α at Myeloma Diagnosis Is Associated with Decreased Survival While Downregulation of IRE1α Expression Is Predictive of Therapy Resistance

Scott R. Goldsmith, MD, Mark A. Fiala, BS, Mark A. Schroeder, MD, Tanya M. Wildes, MD, Armin Ghobadi, MD, Ravi Vij, MBBS, Keith E. Stockerl-Goldstein, MD

Blood (2019) 134 (Supplement_1): 4351.

https://doi.org/10.1182/blood-2019-131135

Published: 2019

Journal Articles

Leukemia-Associated HSC Vascular Niche Is Negatively Regulated By PERK of Unfolded Protein Response (UPR)

Lan Zhou, MD, Cui Liu, MBBS, PhD, Stanley A Adoro, PhD BSc, MSc, Lechuang Chen, PhD, Diana Ramirez, PhD, Ge Jin, PhD

Blood (2019) 134 (Supplement_1): 2486.

https://doi.org/10.1182/blood-2019-127607

Published: 2019

Journal Articles

Evaluation of Clinical Usefulness of Monocyte Gating Using CD14 and CD64 for Detecting PNH Clone By Flow Cytometry

Woo Jae Kwoun, MD, Jeong-Yeal Ahn, MD, Ja Young Seo, MD, Jae Hoon Lee, MD PhD, Hawk Kim, MD PhD, Jinny Park, MD PhD, Kwai Han Yoo, MD, Sung-Ran Cho, MD, Hye Ryoun Kim, MD

Blood (2018) 132 (Supplement 1): 4947.

https://doi.org/10.1182/blood-2018-99-111468

Published: 2018

Journal Articles

Selective Pharmacologic Inhibition of Paroxysmal Nocturnal Hemoglobinuria Clones

Amy C Graham, BS, MS, Alexey Efanov, PhD, Bartlomiej P. Przychodzen, Cassandra M. Hirsch, Vera Adema, PhD, Valeria Visconte, PhD, Jaroslaw P. Maciejewski

Blood (2018) 132 (Supplement 1): 1303.

https://doi.org/10.1182/blood-2018-99-114973

Published: 2018

Journal Articles

Phosphatidylinositol-3,4-Bisphosphate-Akt Signaling Pathway Promotes Platelet Activation

Jasna Marjanovic, Brad Rumancik, Luke Weber, Felix Wangmang, Dane Fickes, Dmitri Postnov, Dung Nguyen, Yoon Lee, Richard Ngo-Lam, Monita Wilson

Blood (2018) 132 (Supplement 1): 1131.

https://doi.org/10.1182/blood-2018-99-115066

Published: 2018

Journal Articles

Manufacture of Clinical-Grade Universal Antigen Presenting Cells (UAPC) for the Ex Vivo Expansion and Activation of Natural Killer (NK) Cells

Enli Liu, MD, Sonny Ang, PhD, Yijiu Tong, Li Li, MD, Rafet Basar, MD, Lucila Kerbauy, MD, May Daher, Pinaki P Banerjee, PhD, Francesca Lorraine Wei Inng Lim, MD, Indreshpal Kaur, PhD, Richard E Champlin, MD, Elizabeth J. Shpall, MD, Katy Rezvani, MD PhD

Blood (2018) 132 (Supplement 1): 2061.

https://doi.org/10.1182/blood-2018-99-118804

Published: 2018

Journal Articles

SHIP1 Inhibition As Novel Therapeutic Approach in Chronic Lymphocytic Leukemia

Veronika Ecker, MSc, Martina Braun, Tanja Neumayer, Markus Muschen, MD, Jürgen Ruland, Maike Buchner, Dr.

Blood (2018) 132 (Supplement 1): 894.

https://doi.org/10.1182/blood-2018-99-117053

Published: 2018

Journal Articles

CRISPR/Cas9 Unsettle PIP4K2A and α, β, and γ Globin Genes Expression

Danaê Malimpensa, BSc, Eliel Faber, MD, Marcus A.F. Corat, PhD, Marlous V.G. Lana, MSc, Bryan E. Strauss, PhD, Fernando F. Costa, MD, PhD, Susan Elisabeth Jorge, MMSc, PhD, Maria de Fátima Sonati, MSc, PhD

Blood (2018) 132 (Supplement 1): 2317.

https://doi.org/10.1182/blood-2018-99-117384

Published: 2018

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

A Phase II Clinical Trial of the Pan PI3K Inhibitor, Buparlisib, for the Treatment of Relapsed and Refractory Chronic Lymphocytic Leukemia: Canadian Cancer Trials Group IND.216

Sarit Assouline, MD, Lilian Amrein, PhD, Versha Banerji, MD FRCP, Stephen Caplan, MD, Carolyn Jane Owen, MD FRCPC, Wanda Hasegawa, MD, Sue Robinson, MD, Sudeep Shavikumar, MD, Anca Prica, MD FRCP(C), Anthea Peters, MSc, MD FRCPC, Linda Hagerman, Laura Rodriguez, Tanya Skamene, MD, Lawrence Panasci, MD, Bingshu E. Chen, Annette E Hay

Blood (2017) 130 (Supplement 1): 4319.

https://doi.org/10.1182/blood.V130.Suppl_1.4319.4319

Published: 2017

Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD

Blood (2017) 130 (Supplement 1): 4290.

https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290

Published: 2017

Journal Articles

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

Daniel N Darlington, PhD, Xiaowu Wu, MD MSc, Andrew P. Cap, MD PhD

Blood (2017) 130 (Supplement 1): 2318.

https://doi.org/10.1182/blood.V130.Suppl_1.2318.2318

Published: 2017

Journal Articles

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Kristy Stengel, PhD, Srividya Bhaskara, PhD, Jing Wang, PhD, Qi Liu, PhD, Scott Hiebert, PhD

Blood (2017) 130 (Supplement 1): 311.

https://doi.org/10.1182/blood.V130.Suppl_1.311.311

Published: 2017

Journal Articles

Overexpression of Phospholipase C Beta 2 Is Associated with Favorable Prognosis in Normal Karyotype Acute Myeloid Leukemia

Jun Hyung Lee, MD MS, Hyun-Jung Choi, MD PhD, Soo-Hyun Kim, MD PhD, Jong-Hee Shin, MD PhD, Soon-Pal Suh, MD PhD, Myung-Geun Shin, MD PhD

Blood (2017) 130 (Supplement 1): 2677.

https://doi.org/10.1182/blood.V130.Suppl_1.2677.2677

Published: 2017

Journal Articles

Elucidation of Autoinflammatory Mechanism in Pigt-PNH

Makiko Osato, MS, Yoshiko Murakami, MD PhD, Shogo Murata, MD PhD, Jun-Ichi Nishimura, MD PhD, Yasutaka Ueda, MD PhD, Taroh Kinoshita, PhD, Yuzuru Kanakura, MD PhD

Blood (2017) 130 (Supplement 1): 2201.

https://doi.org/10.1182/blood.V130.Suppl_1.2201.2201

Published: 2017

Journal Articles

Optimization of Ex Vivo Activation and Expansion of T Cells for Therapy of Lymphoma Via Antagonism of PI3K δ and Vasoactive Intestinal Peptide Signaling

Edmund K. Waller, MD, Mojitabe Hassan, BS, Anna B. Morris, Jasmin Jeffery, Kunhee Lee, Neera Jagirdar, MD, Ashley D. Staton, MD, Christopher Flowers, MD, Cynthia Gaylor, RN, Todd A. Sulchek, PhD, Christopher Thomas Petersen, BS

Blood (2017) 130 (Supplement 1): 3195.

https://doi.org/10.1182/blood.V130.Suppl_1.3195.3195

Published: 2017

Journal Articles

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1679.

https://doi.org/10.1182/blood.V128.22.1679.1679

Published: 2016

NARROW

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

A Multi-Center Dose-Finding Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Fimepinostat (CUDC-907) in Combination with Venetoclax in Patients with Relapsed/Refractory (R/R) Lymphoma

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

The Ire of IRE1α: Overexpression of IRE1α at Myeloma Diagnosis Is Associated with Decreased Survival While Downregulation of IRE1α Expression Is Predictive of Therapy Resistance

Leukemia-Associated HSC Vascular Niche Is Negatively Regulated By PERK of Unfolded Protein Response (UPR)

Evaluation of Clinical Usefulness of Monocyte Gating Using CD14 and CD64 for Detecting PNH Clone By Flow Cytometry

Selective Pharmacologic Inhibition of Paroxysmal Nocturnal Hemoglobinuria Clones

Phosphatidylinositol-3,4-Bisphosphate-Akt Signaling Pathway Promotes Platelet Activation

Manufacture of Clinical-Grade Universal Antigen Presenting Cells (UAPC) for the Ex Vivo Expansion and Activation of Natural Killer (NK) Cells

SHIP1 Inhibition As Novel Therapeutic Approach in Chronic Lymphocytic Leukemia

CRISPR/Cas9 Unsettle PIP4K2A and α, β, and γ Globin Genes Expression

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

A Phase II Clinical Trial of the Pan PI3K Inhibitor, Buparlisib, for the Treatment of Relapsed and Refractory Chronic Lymphocytic Leukemia: Canadian Cancer Trials Group IND.216

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Severe Trauma Leads to a Fall in Intracellular Triphosphates and a Rise in cAMP in Platelets

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Overexpression of Phospholipase C Beta 2 Is Associated with Favorable Prognosis in Normal Karyotype Acute Myeloid Leukemia

Elucidation of Autoinflammatory Mechanism in Pigt-PNH

Optimization of Ex Vivo Activation and Expansion of T Cells for Therapy of Lymphoma Via Antagonism of PI3K δ and Vasoactive Intestinal Peptide Signaling

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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