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Journal Articles

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Minke A. E. Rab, Jennifer Bos, Brigitte A. van Oirschot, Stephanie van Straaten, Penelope A. Kosinski, Victor Chubukov, Hyeryun Kim, Heidi Mangus, Roger E. G. Schutgens, Gerard Pasterkamp, Lenny Dang, Charles Kung, Eduard J. van Beers, Richard van Wijk

Blood (2021) 137 (21): 2997–3001.

https://doi.org/10.1182/blood.2020008635

Published: 2021

Includes: Supplemental data

Journal Articles

Characterization of Bypassing Kinases Inferred By Phosphoproteomics in a Midostaurin Resistant Myeloid Cell Line Model

Mahmoud Hallal, BSc, MSc, Sophie Braga-Lagache, MSc, Jovana Jankovic, Rémy Bruggmann, PhD, Ramanjaneyulu Allam, PhD MSc, BSc, Mario P. Tschan, PhD, Cédric Simillion, PhD, Manfred Heller, PhD, Nicolas Bonadies, MD

Blood (2019) 134 (Supplement_1): 2079.

https://doi.org/10.1182/blood-2019-122337

Published: 2019

Journal Articles

Incidence and Outcomes of Cardiovascular Disease in Hemophilia Patients: An Analysis of National Inpatient Sample Database

Rohit Kumar, MD, Shruti Bhandari, MD, Sunny R K Singh, MD, Sindhu Malapati, MD, Sharad Khurana, MDMSc, Kamila I. Cisak, MD

Blood (2019) 134 (Supplement_1): 2176.

https://doi.org/10.1182/blood-2019-127628

Published: 2019

Journal Articles

Decreased Activity and Stability of Pyruvate Kinase in Hereditary Hemolytic Anemia: A Potential Target for Therapy By AG-348 (Mitapivat), an Allosteric Activator of Red Blood Cell Pyruvate Kinase

Minke A.E. Rab, MD, Brigitte A. van Oirschot, Stephanie van Straaten, MD PhD, Bart J. Biemond, MD PhD, Jennifer Bos, Penelope A. Kosinski, MS, Charles Kung, PhD, Eduard J. van Beers, MD PhD, Richard van Wijk, PhD

Blood (2019) 134 (Supplement_1): 3506.

https://doi.org/10.1182/blood-2019-129996

Published: 2019

Journal Articles

Faster Diagnosis of TTP Using New Technoscreen Adamts-13 Activity Assay

Annica Braf, Henrik von Horn, Niklas Bark, Eva-Marie Norberg, Asa Truedsson, Nikolaus B Binder, MD PhD, Jovan P Antovic, MD PhD

Blood (2019) 134 (Supplement_1): 2354.

https://doi.org/10.1182/blood-2019-128131

Published: 2019

Journal Articles

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Michiel Coppens, MD, Lizhen Xu, PhD, Roisin Bavalia, MD, Saskia Middeldorp, MD PhD, Peter Verhamme, MD PhD, John W. Eikelboom, MBBS, MSc, FRACP, FRCPA, Mark Crowther, MD, Genmin Lu, Patrick Yue, MD, Pamela B. Conley, PhD, Stuart J. Connolly, MD MSc, FRCPC

Blood (2019) 134 (Supplement_1): 711.

https://doi.org/10.1182/blood-2019-124596

Published: 2019

Journal Articles

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

Scott R Best, BS, Vi Lam, Nur Bruss, BS, Taylor Hashiguchi Rowland, BS, Adam S. Kittai, MD, Tingting Liu, Allison J Berger, PhD, Alexey Danilov, MD PhD

Blood (2019) 134 (Supplement_1): 4313.

https://doi.org/10.1182/blood-2019-123600

Published: 2019

Journal Articles

ADAMTS13 Immunohistochemical Expression in Normal and Diseased Equine Tissues

Sherri Flax, MD

Blood (2019) 134 (Supplement_1): 4925.

https://doi.org/10.1182/blood-2019-127407

Published: 2019

Journal Articles

DOCK2 Expression Affects Leukemogenesis and Disease Progression in a Murine Model of FLT3/ITD Acute Myeloid Leukemia

Min Wu, PhD, Li Li, MD PhD, Donald Small, MD PhD, Amy S. Duffield, MD PhD

Blood (2019) 134 (Supplement_1): 2534.

https://doi.org/10.1182/blood-2019-129157

Published: 2019

Journal Articles

Development of Exosome-Capturing Antibody-Conjugated Nucleic Acid Medicines Targeting Multiple Myeloma Cells

Emi Soma, Yuki Toda, PhD, Shigekuni Hosogi, MD PhD, Asako Yamayoshi, PhD, Eishi Ashihara, MD PhD

Blood (2019) 134 (Supplement_1): 3365.

https://doi.org/10.1182/blood-2019-121995

Published: 2019

Journal Articles

Identification of Genotype-Specific Therapeutic Vulnerabilities By Comparative Dynamic BH3 Profiling Analysis of Human and Murine CLL

Shanye Yin, PhD, Salma Parvin, PhD, Elisa Ten Hacken, PhD, Rebecca Valentin, MD, Heather Joyal, Laura Z. Rassenti, PhD, Emanuela M. Ghia, PhD, Thomas J. Kipps, MD PhD, Donna S Neuberg, ScD, Lili Wang, MD PhD, Matthew S. Davids, MD, Ruben D. Carrasco, MD PhD, Anthony G. Letai, MD PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 4281.

https://doi.org/10.1182/blood-2019-127293

Published: 2019

Journal Articles

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies

Blood (2019) 134 (Supplement_1): 877.

https://doi.org/10.1182/blood-2019-131255

Published: 2019

Journal Articles

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Olukemi Amodu, PhD, Binal N. Shah, Subulade Ademola, PhD, Bamidele Tayo, PhD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 942.

https://doi.org/10.1182/blood-2019-132190

Published: 2019

Journal Articles

Myeloma bone disease: from biology findings to treatment approaches

Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Meletios A. Dimopoulos

Blood (2019) 133 (14): 1534–1539.

https://doi.org/10.1182/blood-2018-11-852459

Published: 2019

Journal Articles

Changes in Factor VIII:C Activity over 24 Hours Depending on Diluent and Storage Conditions after Dilution

Shin Young Hyun, MD, Kun soo Lee, MD PhD, Yu Ri Kim, MD

Blood (2018) 132 (Supplement 1): 2488.

https://doi.org/10.1182/blood-2018-99-120288

Published: 2018

Journal Articles

Macrophage Polarization Is Impaired in Hemophilia

Lynn M Knowles, PhD, Daniela Lessig, Martin Bernard, Eva C Schwarz, PhD, Hermann Eichler, MD, Jan Pilch, MD

Blood (2018) 132 (Supplement 1): 2499.

https://doi.org/10.1182/blood-2018-99-117111

Published: 2018

Journal Articles

Leukemia Stem Cells in Relapsed AML Patients Are Uniquely Dependent on Nicotinamide Metabolism

Courtney L Jones, PhD, Brett M Stevens, PhD, Rachel Culp-Hill, BS, Travis Nemkov, Angelo D'Alessandro, PhD, Shanshan Pei, PhD, Daniel A Pollyea, MD, Craig T Jordan, PhD

Blood (2018) 132 (Supplement 1): 429.

https://doi.org/10.1182/blood-2018-99-111366

Published: 2018

Journal Articles

Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 428.

https://doi.org/10.1182/blood-2018-99-118745

Published: 2018

Journal Articles

Tibetan Enriched PKLR Variant Is Beneficial to High Altitude Adaption By Improving Oxygen Delivery

Jihyun Song, PhD, Virginia Abello, MD, Ricardo Amaru, MD, Adelina Sergueeva, MD, Jainagul Isakova, Penelope A. Kosinski, MS, Brigitte A. van Oirschot, Victor R. Gordeuk, MD, Charles Kung, PhD, Richard van Wijk, PhD, Josef T. Prchal, MD

Blood (2018) 132 (Supplement 1): 1027.

https://doi.org/10.1182/blood-2018-99-117389

Published: 2018

Journal Articles

Novel Small Molecule Stimulants of Hematopoietic Stem Cells and Their Mode of Action

Sergei Vatolin, PhD, Jaroslaw P. Maciejewski

Blood (2018) 132 (Supplement 1): 1302.

https://doi.org/10.1182/blood-2018-99-114838

Published: 2018

NARROW

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Characterization of Bypassing Kinases Inferred By Phosphoproteomics in a Midostaurin Resistant Myeloid Cell Line Model

Incidence and Outcomes of Cardiovascular Disease in Hemophilia Patients: An Analysis of National Inpatient Sample Database

Decreased Activity and Stability of Pyruvate Kinase in Hereditary Hemolytic Anemia: A Potential Target for Therapy By AG-348 (Mitapivat), an Allosteric Activator of Red Blood Cell Pyruvate Kinase

Faster Diagnosis of TTP Using New Technoscreen Adamts-13 Activity Assay

Effects of Andexanet Alfa on Thrombin Generation in Bleeding Associated with Factor Xa Inhibitors

Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies

ADAMTS13 Immunohistochemical Expression in Normal and Diseased Equine Tissues

DOCK2 Expression Affects Leukemogenesis and Disease Progression in a Murine Model of FLT3/ITD Acute Myeloid Leukemia

Development of Exosome-Capturing Antibody-Conjugated Nucleic Acid Medicines Targeting Multiple Myeloma Cells

Identification of Genotype-Specific Therapeutic Vulnerabilities By Comparative Dynamic BH3 Profiling Analysis of Human and Murine CLL

The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies

Relationship of Host Genetic Factors with Severe Malaria in Nigerian Children

Myeloma bone disease: from biology findings to treatment approaches

Changes in Factor VIII:C Activity over 24 Hours Depending on Diluent and Storage Conditions after Dilution

Macrophage Polarization Is Impaired in Hemophilia

Leukemia Stem Cells in Relapsed AML Patients Are Uniquely Dependent on Nicotinamide Metabolism

Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia

Tibetan Enriched PKLR Variant Is Beneficial to High Altitude Adaption By Improving Oxygen Delivery

Novel Small Molecule Stimulants of Hematopoietic Stem Cells and Their Mode of Action

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American Society of Hematology

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ASH Publications

American Society of Hematology

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