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Stephanie van Straaten
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Journal Articles

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Minke A. E. Rab, Jennifer Bos, Brigitte A. van Oirschot, Stephanie van Straaten, Penelope A. Kosinski, Victor Chubukov, Hyeryun Kim, Heidi Mangus, Roger E. G. Schutgens, Gerard Pasterkamp, Lenny Dang, Charles Kung, Eduard J. van Beers, Richard van Wijk
Journal: Blood
Blood (2021) 137 (21): 2997–3001.
https://doi.org/10.1182/blood.2020008635
Published: 2021
Includes: Supplemental data
Journal Articles

Erythropoietin Is Associated with a Decline in the iFGF23/cFGF23 Ratio in Patients with Various Hereditary Hemolytic Anemias

Annelies J. Van Vuren, MD, Michele F. Eisenga, MD PhD, Stephanie van Straaten, MD PhD, Andreas Glenthøj, MD PhD, Carlo A.J.M. Gaillard, MD PhD, Stephan J.L. Bakker, MD PhD, Martin H. de Borst, MD PhD, Richard van Wijk, PhD, Eduard J. van Beers, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4793.
https://doi.org/10.1182/blood-2019-124074
Published: 2019
Journal Articles

A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease from Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling

Annelies J. Van Vuren, MD, Stephanie van Straaten, MD PhD, Michal Mokry, PhD, Richard van Wijk, PhD, Eduard J. van Beers, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 980.
https://doi.org/10.1182/blood-2019-124070
Published: 2019
Journal Articles

Decreased Activity and Stability of Pyruvate Kinase in Hereditary Hemolytic Anemia: A Potential Target for Therapy By AG-348 (Mitapivat), an Allosteric Activator of Red Blood Cell Pyruvate Kinase

Minke A.E. Rab, MD, Brigitte A. van Oirschot, Stephanie van Straaten, MD PhD, Bart J. Biemond, MD PhD, Jennifer Bos, Penelope A. Kosinski, MS, Charles Kung, PhD, Eduard J. van Beers, MD PhD, Richard van Wijk, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3506.
https://doi.org/10.1182/blood-2019-129996
Published: 2019
Journal Articles

Phosphatidylserine-Exposing Extracellular Vesicles after Splenectomy Are Associated with Increased D-Dimers and Fibrin Generation in Hereditary Hemolytic Anemia

Stephanie Van Straaten, MD, Chi Hau, Najat Hajji, Jill Verhoeven, Roger Schutgens, MD PhD MSc, Wouter van Solinge, PhD, Richard van Wijk, PhD, Rienk Nieuwland, PhD, Eduard J. van Beers, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 630.
https://doi.org/10.1182/blood-2018-99-110918
Published: 2018