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Journal Articles

Increased activation of PI3 kinase-δ predisposes to B-cell lymphoma

Anne Durandy, Sven Kracker

Blood (2020) 135 (9): 638–643.

https://doi.org/10.1182/blood.2019002072

Published: 2020

Journal Articles

Prophylactic Itacitinib (INCB039110) for the Prevention of Cytokine Release Syndrome Induced By Chimeric Antigen Receptor T-Cells (CAR-T-cells) Therapy

Eduardo Huarte, PhD, Roddy S O'Connor, PhD, Melissa Parker, Taisheng Huang, Michael C. Milone, Paul Smith

Blood (2019) 134 (Supplement_1): 1934.

https://doi.org/10.1182/blood-2019-128288

Published: 2019

Journal Articles

Antiretroviral Therapy Does Not Correct the Increased Thrombin Generation and Platelet Hyperactivity Associated with HIV

Meenakshi Banerjee, PhD, Martha Sim, Thein Myint, MD, Sidney W. Whiteheart, PhD, Jeremy P. Wood, PhD

Blood (2019) 134 (Supplement_1): 3659.

https://doi.org/10.1182/blood-2019-130070

Published: 2019

Journal Articles

Ixazomib Modulates Bone Remodeling and Actives Sonic Hedgehog Pathways

Daniele Tibullo, PhD, Anna Longo, PhD, Alessandra Romano, MD PhD, Alessandro Barbato, Cesarina Giallongo, PhD, Michelino Di Rosa, PhD, Carmelina Daniela Anfuso, Gabriella Lupo, Concetta Conticello, MD, Nunzio Vicario, PhD, Rosario Gulino, PhD, Rosalba Parenti, PhD, Giuseppe A. Palumbo, MD PhD, Giovanni Li Volti, MD PhD, Francesco Di Raimondo, MD

Blood (2019) 134 (Supplement_1): 4345.

https://doi.org/10.1182/blood-2019-129927

Published: 2019

Journal Articles

Evaluation of a Blood Coagulation Factor IX Variant That Functions Independently of Factor VIII As an Alternative Treatment for Hemophilia A

Viola J.F. Strijbis, MSc, Ka Lei Cheung, Pavlina Konstantinova, PhD, Ying Poi Liu, PhD, Sander J van Deventer, MD PhD, Mettine H.A. Bos, PhD

Blood (2019) 134 (Supplement_1): 1110.

https://doi.org/10.1182/blood-2019-124120

Published: 2019

Journal Articles

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Vinothini Govindarajah, PhD, Jung-Mi Lee, PhD, Michael Solomon, Bryan Goddard, Ramesh C. Nayak, PhD, Jose A Cancelas, MD, Damien Reynaud

Blood (2019) 134 (Supplement_1): 1201.

https://doi.org/10.1182/blood-2019-127222

Published: 2019

Journal Articles

Pyruvate Kinase Deficiency Cases Mimicking Congenital Dyserythropoietic Anemia

Sule Unal, MD, Tekin Aksu, MD, Cagrı Coskun, MD, Fatma Gumruk, MD

Blood (2019) 134 (Supplement_1): 4794.

https://doi.org/10.1182/blood-2019-124272

Published: 2019

Journal Articles

The Complete Dependence of Factor IX Padua (R338L) Hyperactivity on Factor VIIIa Cofactor Activity Supports Its Safety As a Transgene for Hemophilia B Gene Therapy

Benjamin J. Samelson-Jones, MD PhD, John D. Finn, PhD, Rodney M. Camire, PhD, Valder R Arruda, MD PhD

Blood (2018) 132 (Supplement 1): 3486.

https://doi.org/10.1182/blood-2018-99-119270

Published: 2018

Journal Articles

Potential IL6R-ADAR1-STAT3 Interplay Promotes Oncogenicity in 1q21(amp) Multiple Myeloma

Phaik Ju Teoh, PhD, Tae-Hoon Chung, Leilei Chen, PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS

Blood (2018) 132 (Supplement 1): 4513.

https://doi.org/10.1182/blood-2018-99-118895

Published: 2018

Journal Articles

Bleeding Events and Safety Outcomes in Pediatric Persons with Hemophilia A with Inhibitors: The First Non-Interventional Study (NIS) from a Real-World Setting

Johannes Oldenburg, Midori Shima, MDPhD, Rebecca Kruse-Jarres, Elena Santagostino, Johnny Mahlangu, Nives Selak Bienz, Sammy Chebon, Elina Asikanius, Gallia G. Levy

Blood (2017) 130 (Supplement 1): 1089.

https://doi.org/10.1182/blood.V130.Suppl_1.1089.1089

Published: 2017

Journal Articles

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

Jianhong Lin, MD MSc, Chun Yang, MD PhD, Li Xue, MD PhD, Zhenkui Wang, MD PhD, Yan Xu, MD, Mehmet Kemal Samur, PhD, Jianjun Zhao, MD, Ariel Kwart, BS, Masood A. Shammas, PhD, Xiaofeng Jiang, MD PhD, Wong Kwok-Kin, MD PhD, Ruben D. Carrasco, MD PhD, Kenneth C Anderson, MD, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 4410.

https://doi.org/10.1182/blood.V130.Suppl_1.4410.4410

Published: 2017

Journal Articles

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Pavel Davizon-Castillo, MD, Ken L. Jones, PhD, Sonia Aguila, PhD, David Bark, PhD, Katrina J. Ashworth, MS, Kelly Higa, MS, Eric Martin Pietras, PhD, Robert A. Campbell, PhD, Lauren Christine Shih, BA, Natalie Saunders, MD, James DeGregori, Matthew T. Rondina, MD, Jorge Di Paola, MD

Blood (2017) 130 (Supplement 1): 292.

https://doi.org/10.1182/blood.V130.Suppl_1.292.292

Published: 2017

Journal Articles

Novel Combination Therapies with the RNA Polymerase I Inhibitor CX-5461 Significantly Improve Efficacy in Multiple Myeloma

Kylee H Maclachlan, FRACP,FRCPA, Andrew Cuddihy, PhD, Nadine Hein, PhD, Carleen Cullinane, PhD, Simon J. Harrison, MBBS,MRCP,FRCPath,FRACP,PhD, Ross Hannan, PhD, Gretchen Poortinga, PhD

Blood (2017) 130 (Supplement 1): 1805.

https://doi.org/10.1182/blood.V130.Suppl_1.1805.1805

Published: 2017

Journal Articles

Indoxyl sulfate induces platelet hyperactivity and contributes to chronic kidney disease–associated thrombosis in mice

Ke Yang, Changhong Du, Xinmiao Wang, Fengju Li, Yang Xu, Song Wang, Shilei Chen, Fang Chen, Mingqiang Shen, Mo Chen, Mengjia Hu, Ting He, Yongping Su, Junping Wang, Jinghong Zhao

Blood (2017) 129 (19): 2667–2679.

https://doi.org/10.1182/blood-2016-10-744060

Published: 2017

Includes: Supplemental data

Journal Articles

New Hyperactive Factor IX Variants Bioengineered Based upon Biochemical Studies of Factor IX Padua

Ben J. Samelson-Jones, MD PhD, Jonathan D Finn, PhD, Rodney M. Camire, PhD, Valder R Arruda, MD PhD

Blood (2016) 128 (22): 1384.

https://doi.org/10.1182/blood.V128.22.1384.1384

Published: 2016

Journal Articles

Molecular Mechanisms of Ibrutinib Resistance: Defining a Logical Approach to Improving Targeted Therapy in CLL

Sara MK Farag, MBBCh, MSc in MDcal sciences, Darren Newton, PhD, Gina Doody, Associate Professor, Molecular Immunology, Lotfy Abdelnaby Mahmoud, Professor of Haematology, Manal Ibrahim Fouda, Professor of Haematology, Doaa Mahmoud El Ghannam, Professor of Clinical Pathology, Peter Hillmen

Blood (2016) 128 (22): 2046.

https://doi.org/10.1182/blood.V128.22.2046.2046

Published: 2016

Journal Articles

Blood Clot Contraction (Retraction) Is Impaired in Acute Ischemic Stroke

Valerie Tutwiler, Alina Peshkova, Dina Khasanova, MD, John W. Weisel, Rustem I. Litvinov, PhD

Blood (2016) 128 (22): 4998.

https://doi.org/10.1182/blood.V128.22.4998.4998

Published: 2016

Journal Articles

Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging

Pavel Davizon-Castillo, Katrina Ashworth, MS, Kelly Higa, MS, Giovanny Hernandez, Sumitra Acharya, Robert A. Campbell, PhD, Matthew Rondina, MD, Colm B. Collins, PhD, Anthony Donato, MD, Lisa Lesniewski, James DeGregori, Michael Holer, Nirmal Banda, Jorge Di Paola, MD, Eric Martin Pietras, PhD

Blood (2016) 128 (22): 3747.

https://doi.org/10.1182/blood.V128.22.3747.3747

Published: 2016

Journal Articles

Parent-Reported and Self-Perceived Behavioral and Psychiatric Symptoms in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia

Wei Liu, PhD, Yin Ting Cheung, PhD, Tara M. Brinkman, PhD, Pia Banerjee, PhD, Deokumar Srivastava, PhD, Vikki G Nolan, DSc, MPH, Hongmei Zhang, PhD, James G Gurney, PhD, Ching-Hon Pui, MD, Leslie L. Robison, PhD, Melissa M. Hudson, MD, Kevin R. Krull, PhD

Blood (2016) 128 (22): 3594.

https://doi.org/10.1182/blood.V128.22.3594.3594

Published: 2016

Journal Articles

Pure Red Cell Aplasia - a New Manifestation of CTLA4 Mutation

Ingunn Dybedal, MDPhD, Anna Mari Lone, PhD, Hanne Sørmo Sorte, MSc, Lorant Farkas, MD PhD, Jürgen Rolke, MD, Robert Brudevold, MD, Asbjørg Stray-Pedersen, MD PhD, Kjetil Tasken, MD PhD

Blood (2015) 126 (23): 2225.

https://doi.org/10.1182/blood.V126.23.2225.2225

Published: 2015

NARROW

Increased activation of PI3 kinase-δ predisposes to B-cell lymphoma

Prophylactic Itacitinib (INCB039110) for the Prevention of Cytokine Release Syndrome Induced By Chimeric Antigen Receptor T-Cells (CAR-T-cells) Therapy

Antiretroviral Therapy Does Not Correct the Increased Thrombin Generation and Platelet Hyperactivity Associated with HIV

Ixazomib Modulates Bone Remodeling and Actives Sonic Hedgehog Pathways

Evaluation of a Blood Coagulation Factor IX Variant That Functions Independently of Factor VIII As an Alternative Treatment for Hemophilia A

Disruption of the Akt-FoxO Axis As a Safeguard Mechanism for the Hematopoietic Stem Cell Compartment during Chronic Metabolic Stress

Pyruvate Kinase Deficiency Cases Mimicking Congenital Dyserythropoietic Anemia

The Complete Dependence of Factor IX Padua (R338L) Hyperactivity on Factor VIIIa Cofactor Activity Supports Its Safety As a Transgene for Hemophilia B Gene Therapy

Potential IL6R-ADAR1-STAT3 Interplay Promotes Oncogenicity in 1q21(amp) Multiple Myeloma

Bleeding Events and Safety Outcomes in Pediatric Persons with Hemophilia A with Inhibitors: The First Non-Interventional Study (NIS) from a Real-World Setting

A Single Gene-Mediated Perturbation of the Human Genome Leads to Malignant Transformation in a Murine Transgenic Model

Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets

Novel Combination Therapies with the RNA Polymerase I Inhibitor CX-5461 Significantly Improve Efficacy in Multiple Myeloma

Indoxyl sulfate induces platelet hyperactivity and contributes to chronic kidney disease–associated thrombosis in mice

New Hyperactive Factor IX Variants Bioengineered Based upon Biochemical Studies of Factor IX Padua

Molecular Mechanisms of Ibrutinib Resistance: Defining a Logical Approach to Improving Targeted Therapy in CLL

Blood Clot Contraction (Retraction) Is Impaired in Acute Ischemic Stroke

Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging

Parent-Reported and Self-Perceived Behavioral and Psychiatric Symptoms in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia

Pure Red Cell Aplasia - a New Manifestation of CTLA4 Mutation

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American Society of Hematology

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American Society of Hematology

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