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Journal Articles

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells

Blood (2021) 137 (19): 2598–2608.

https://doi.org/10.1182/blood.2020008503

Published: 2021

Includes: Supplemental data

Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Tamar Aprahamian, PhD, ED Keniston, Jane Branca, Muneer G Hasham, PhD, Melinda Day, PhD, Kevin Mills, PhD

Blood (2019) 134 (Supplement_1): 2330.

https://doi.org/10.1182/blood-2019-131311

Published: 2019

Journal Articles

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Blood (2019) 134 (Supplement_1): 393.

https://doi.org/10.1182/blood-2019-131270

Published: 2019

Journal Articles

Effects of Actr2 gene Variants on Mouse Viability, Gene Expression, and Cytoskeletal Dynamics

Linzi M Hobbs, BS, Amy E Siebert, PhD, Alexander J Johnston, BS, Marisa A Brake, BSc, Vakharia Paras, PharmD, MD, Cleuren Audrey, PhD, Guojing Zhu, MD, Randal J Westrick, PhD

Blood (2019) 134 (Supplement_1): 2340.

https://doi.org/10.1182/blood-2019-131004

Published: 2019

Journal Articles

Efficient Correction of ELANE mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/Cas9 and rAVV6 HDR Repair Templates

Malte U Ritter, Benjamin Secker, Maksim Klimiankou, Masoud Nasri, MSc, Narges Aghaallaei, Benjamin Dannenmann, Regine Bernhard, Ingeborg Steiert, Karin Haehnel, Baubak Bajoghli, Cornelia Zeidler, Karl Welte, Julia Skokowa, MD PhD

Blood (2019) 134 (Supplement_1): 1036.

https://doi.org/10.1182/blood-2019-131708

Published: 2019

Journal Articles

CYT01B, a Novel RAD51 Inhibitor, Act Synergistically with Both Targeted and Chemotherapeutic Anti-Cancer Agents

Tyler Maclay, Joseph Vacca, Casey McComas, Alfredo Castro, Melinda Day, PhD, Kevin Mills, PhD

Blood (2018) 132 (Supplement 1): 3963.

https://doi.org/10.1182/blood-2018-99-119373

Published: 2018

Journal Articles

Conversion of T-Effector Cells to Immunosuppressive T-Regulatory-like Cells By CRISPR/Cas9-Mediated Integration of a FOXP3 Transgene

Yuchi Honaker, PhD, Yufei Xiang, MD, PhD, Logan Fisher, B.S., Karen Sommer, PhD, Troy R. Torgerson, MD PhD, Andrew M. Scharenberg, MD, David J. Rawlings, MD

Blood (2018) 132 (Supplement 1): 3490.

https://doi.org/10.1182/blood-2018-99-117456

Published: 2018

Journal Articles

A Precise Tool to Edit Human Hematopoietic Stem Cells at High Efficiency and Decipher and Optimize the Different Double Strand Break Repair Outcomes

Rajeswari Jayavaradhan, MS, Devin Pillis, MS, Sarah McGraw, Loberg Anastacia, Paul R. Andreassen, PhD, Punam Malik, MD

Blood (2017) 130 (Supplement 1): 2067.

https://doi.org/10.1182/blood.V130.Suppl_1.2067.2067

Published: 2017

Journal Articles

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

Blood (2017) 130 (2): 156–166.

https://doi.org/10.1182/blood-2016-12-758219

Published: 2017

Includes: Supplemental data

Journal Articles

Differential Expression of the Homologous Recombination DNA Repair Genes in Early and Advanced Stages of Myelodysplastic Syndrome

Jan Valka, MD, Jitka Vesela, Hana Votavova, PhD, Anna Jonasova, MD PhD, Jaroslav Cermak, MD PhD, Monika Belickova

Blood (2016) 128 (22): 5513.

https://doi.org/10.1182/blood.V128.22.5513.5513

Published: 2016

Journal Articles

A Novel Role of PALB2 in Lymphoid Tumour Development

Tatjana Stankovic, MD PhD, Philip J Byrd, PhD, Grant S Stewart, PhD, Alexander J Taylor, Anna Smith, Peggy Fooks, Robert Horsley, James I Last, PhD, Dragana Janic, MD PhD, Lidija Dokmanovic, MD PhD, Antony W Oliver, PhD, A.Malcolm R Taylor, PhD

Blood (2016) 128 (22): 5113.

https://doi.org/10.1182/blood.V128.22.5113.5113

Published: 2016

Journal Articles

Customizing the genome as therapy for the β-hemoglobinopathies

Matthew C. Canver, Stuart H. Orkin

Blood (2016) 127 (21): 2536–2545.

https://doi.org/10.1182/blood-2016-01-678128

Published: 2016

Journal Articles

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Nanyan Zhang, MD PhD, Jamie Foeckler, Shawn Kalloway, PhD, Sridhar Rao, MD PhD, Brian R Curtis, PhD D(ABMLI), Hartmut Weiler, PhD, Peter J. Newman, PhD

Blood (2015) 126 (23): 2341.

https://doi.org/10.1182/blood.V126.23.2341.2341

Published: 2015

Journal Articles

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

Tzung-Huei Lai, PhD, Alma Zecevic, Brett Ewald, PhD, Liu Chaomei, Lara Rizzotto, PhD, Melanie Sulda, Dimitrios Papaioannou, MD, Ramiro Garzon, MD, William Plunkett, PhD, Deepa Sampath, PhD

Blood (2015) 126 (23): 3639.

https://doi.org/10.1182/blood.V126.23.3639.3639

Published: 2015

Journal Articles

Epigenetic Silencing of BRCA1 Is Linked to Homologous Recombination Repair Defects and Elevated Mir-155 Expression in Myeloid Neoplasms

Weijie Poh, BS, Alison R Moliterno, MD, Keith W. Pratz, MD, Ivana Gojo, MD, Michael A McDevitt, MD PhD, James G. Herman, MD

Blood (2014) 124 (21): 3525.

https://doi.org/10.1182/blood.V124.21.3525.3525

Published: 2014

Journal Articles

Generation of Cell Lines Harboring SETBP1 Mutations By the Crispr/Cas9 System

Nozomu Kawashima, MD, Yusuke Okuno, MD PhD, Yuko Sekiya, MD, Xinan Wang, Yinyan Xu, PhD, Atsushi Narita, MD, Sayoko Doisaki, MD, Michi Kamei, MD, Hideki Muramatsu, MD PhD, Masahiro Irie, MD PhD, Asahito Hama, MD PhD, Yoshiyuki Takahashi, MD, PhD, Seiji Kojima, MD PhD

Blood (2014) 124 (21): 4622.

https://doi.org/10.1182/blood.V124.21.4622.4622

Published: 2014

Journal Articles

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

Nanyan Zhang, MD PhD, Huiying Zhi, MD PhD, Sridhar Rao, Peter J. Newman, PhD

Blood (2014) 124 (21): 573.

https://doi.org/10.1182/blood.V124.21.573.573

Published: 2014

Journal Articles

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Subodh Kumar, PhD, Jagannath Pal, PhD, Jialan Shi, PhD, Puru Nanjappa, MS, Maria Gkotzamanidou, MD, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1248.

https://doi.org/10.1182/blood.V122.21.1248.1248

Published: 2013

Journal Articles

Internal Tandem Duplication Mutation Of FLT3 (FLT3/ITD) Induces Increased Homologous Recombination DNA Repair Activity, Drug Resistance and Sister Chromatid Exchanges In Acute Myeloid Leukaemia (AML)

Terry J Gaymes, DPhil, David C Darling, PhD, Ghulam J. Mufti, MD, PhD

Blood (2013) 122 (21): 1244.

https://doi.org/10.1182/blood.V122.21.1244.1244

Published: 2013

NARROW

Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Effects of Actr2 gene Variants on Mouse Viability, Gene Expression, and Cytoskeletal Dynamics

Efficient Correction of ELANE mutations in Primary HSPCs of Severe Congenital Neutropenia Patients Using CRISPR/Cas9 and rAVV6 HDR Repair Templates

CYT01B, a Novel RAD51 Inhibitor, Act Synergistically with Both Targeted and Chemotherapeutic Anti-Cancer Agents

Conversion of T-Effector Cells to Immunosuppressive T-Regulatory-like Cells By CRISPR/Cas9-Mediated Integration of a FOXP3 Transgene

A Precise Tool to Edit Human Hematopoietic Stem Cells at High Efficiency and Decipher and Optimize the Different Double Strand Break Repair Outcomes

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status

Differential Expression of the Homologous Recombination DNA Repair Genes in Early and Advanced Stages of Myelodysplastic Syndrome

A Novel Role of PALB2 in Lymphoid Tumour Development

Customizing the genome as therapy for the β-hemoglobinopathies

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

HDAC Inhibition Induces microRNA-182 Which Targets Rad51 Protein and Impairs Homologous Recombination Repair to Sensitize Cells to the Double Strand Break Inducing Nucleoside Analog, Sapacitabine in AML

Epigenetic Silencing of BRCA1 Is Linked to Homologous Recombination Repair Defects and Elevated Mir-155 Expression in Myeloid Neoplasms

Generation of Cell Lines Harboring SETBP1 Mutations By the Crispr/Cas9 System

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Internal Tandem Duplication Mutation Of FLT3 (FLT3/ITD) Induces Increased Homologous Recombination DNA Repair Activity, Drug Resistance and Sister Chromatid Exchanges In Acute Myeloid Leukaemia (AML)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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