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Journal Articles

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

Ravi Dashnamoorthy, PhD, Afshin Beheshti, PhD, Xiaoyang Su, PhD, Ying Chen, PhD, Maisarah Mokhtar, B.S, Gregory Dolnikowski, Frederick Lansigan, MD, William B Kinlaw, III, MD, Sandeep Dave, MD, Andrew M. Evens, DO, MSc

Blood (2019) 134 (Supplement_1): 1573.

https://doi.org/10.1182/blood-2019-126382

Published: 2019

Journal Articles

High Glycine Promotes Proliferation and Progression Though Increase of Glutathione Synthesis in Multiple Myeloma

Jiliang Xia, PhD, Jingyu Zhang, Bin Meng, Xuan Wu, Qian Lei, Yinghong Zhu, Yanjuan He, MD, Lugui Qiu, MD PhD, Wei Jia, PhD, Wen Zhou, PhD

Blood (2019) 134 (Supplement_1): 1791.

https://doi.org/10.1182/blood-2019-125452

Published: 2019

Journal Articles

Decitabine Induces Ferroptosis in Myelodysplastic Syndrome

Qi Lv, Master of MDcine, Huaquan Wang, MD, Zonghong Shao, MD, Limin Xing, Lanzhu Yue, MD, Jiaxi Liu

Blood (2019) 134 (Supplement_1): 2995.

https://doi.org/10.1182/blood-2019-122000

Published: 2019

Journal Articles

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Jonathan Rink, PhD, Adam Yuh Lin, MD PhD, Shuo Yang, PhD, Amir Behdad, MD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD

Blood (2019) 134 (Supplement_1): 2857.

https://doi.org/10.1182/blood-2019-127805

Published: 2019

Journal Articles

Linking Stored Red Blood Cell Metabolism to Transfusion Recipient Iron Homeostasis Pathophysiology in Critically-Ill Children

Ryan M. Fredericks, MD, Travis Nemkov, PhD, Camilla L'Acqua, MD, Steven L. Spitalnik, MD, Eldad A. Hod, MD, Angelo D'Alessandro, PhD

Blood (2019) 134 (Supplement_1): 1175.

https://doi.org/10.1182/blood-2019-125854

Published: 2019

Journal Articles

Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model

John D Belcher, PhD, Margaret Biddle, PhD, Domi Stickens, PhD, Lyndsay Olson, Eric Bell, Chunsheng Chen, Fuad Abdulla, Julia Nguyen, Zachary Monroe Kiser, BS, PhD, Jacob Lloyd, MD, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 983.

https://doi.org/10.1182/blood-2019-127300

Published: 2019

Journal Articles

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Blood (2019) 134 (Supplement_1): 806.

https://doi.org/10.1182/blood-2019-128930

Published: 2019

Journal Articles

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Dipti Gupta, Samuel Lessard, PhD, Nancy Moore, Jicheng Duan, PhD, Yukio Nakamura, MD PhD, Feng-Chun Yang, MD PhD, Alexandra Hicks, PhD, David R. Light, PhD, Sriram Krishnamoorthy, PhD

Blood (2019) 134 (Supplement_1): 210.

https://doi.org/10.1182/blood-2019-129479

Published: 2019

Journal Articles

Glutathione Metabolism Contributes to the Pathobiology of Waldenstrom's Macroglobulinemia

Shahrzad Jalali, PhD, Jie Shi, MD PhD, Hyojin Kim, PhD, Zhi-Zhang Yang, MD, Stephen M Ansell, MD

Blood (2019) 134 (Supplement_1): 3971.

https://doi.org/10.1182/blood-2019-124558

Published: 2019

Journal Articles

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Mileidys Perez-Alea, Sr., PhD, Julien Colle, Jr., MD, Muhube Yazir, Jr., MSc, Céline Baier, Jr., PhD, Yasmine Labiad, PhD, Isabelle Arnoux, Sr., Hematologist, Geoffroy Venton, Jr., PhD MD, Guillaume Guillaume, MSc, Ismail Ceylan, MSc, Regis T. Costello, Sr., MD PhD

Blood (2019) 134 (Supplement_1): 3364.

https://doi.org/10.1182/blood-2019-126484

Published: 2019

Journal Articles

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Wenqing Wang, PhD, Avni Awani, PhD, Andrew Devilbiss, PhD, Thomas Mathews, PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Sean Morrison, PhD, Katja G Weinacht, MD PhD

Blood (2019) 134 (Supplement_1): 3705.

https://doi.org/10.1182/blood-2019-129424

Published: 2019

Journal Articles

Identification of Novel Variants Associated with Fetal Hemoglobin Levels in Healthy Donors (the INTERVAL study)

Emily Kawabata, Samuel Lessard, PhD, Dirk Paul, Paola G Bronson, Robert Peters, Sriram Krishnamoorthy, PhD, William Astle, Adam Butterworth

Blood (2019) 134 (Supplement_1): 2243.

https://doi.org/10.1182/blood-2019-123977

Published: 2019

Journal Articles

Untargeted Metabolomics on Dried Blood Spots for the Diagnosis and Clinical Follow up of Rare Hereditary Anemias

Birgit van Dooijeweert, MD, Melissa Broeks, Msc, Judith Jans, PhD, Eduard J. van Beers, MD PhD, Nanda Verhoeven, PhD, Richard van Wijk, PhD, Marije Bartels, MD PhD

Blood (2019) 134 (Supplement_1): 3376.

https://doi.org/10.1182/blood-2019-131693

Published: 2019

Journal Articles

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, Rachel Culp-Hill, Julie A. Reisz, Shanshan Pei, Annika Gustafson, Nabilah Khan, James DeGregori, Daniel A. Pollyea, Craig T. Jordan

Blood (2019) 134 (4): 389–394.

https://doi.org/10.1182/blood.2019898114

Published: 2019

Includes: Supplemental data

Journal Articles

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Blood (2018) 132 (Supplement 1): 4020.

https://doi.org/10.1182/blood-2018-99-117310

Published: 2018

Journal Articles

Targeting Autophagy Kinase ULK1 Can Reverse Bcl2 Inhibitor (ABT-199) Induced Autophagy to Overcome Acquired Resistance in Acute Myeloid Leukemia

Seemana Bhattacharya, PhD, Sujan Piya, PhD, Qi Zhang, PhD, Natalia Baran, PhD MD, Teresa McQueen, MS, R. Eric Davis, MD, Nicholas Cosford, PhD, Marina Y. Konopleva, MD PhD, Michael Andreeff, MD PhD, Gautam Borthakur, MD

Blood (2018) 132 (Supplement 1): 3934.

https://doi.org/10.1182/blood-2018-99-114817

Published: 2018

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Blood (2018) 132 (Supplement 1): 2543.

https://doi.org/10.1182/blood-2018-99-119262

Published: 2018

Journal Articles

Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation

Giorgia Simonetti, PhD, Samantha Bruno, Carmine Onofrillo, PhD, Cristina Papayannidis, Giovanni Marconi, Michele Cavo, MD, Lorenzo Montanaro, MD PhD, Giovanni Martinelli

Blood (2018) 132 (Supplement 1): 2639.

https://doi.org/10.1182/blood-2018-99-117429

Published: 2018

Journal Articles

Hydroxyurea Exhibits Antioxidant Activity Via the Nrf2 Pathway- Antioxidant/Electrophile Response Element Regulated By p62/ SQSTM1

Sanzio Santana, MSc, Thassila Nogueira Pitanga, PhD, Jeanne Machado de Santana, Graduation student, Dalila Lucíola Zanette, PhD, Corynne Stephanie A. Adanho, MSc, Nívea Farias Luz, PhD, Valéria Matos Borges, PhD, Marilda Souza Goncalves

Blood (2018) 132 (Supplement 1): 3648.

https://doi.org/10.1182/blood-2018-99-117220

Published: 2018

NARROW

Identification of FASN-Dependent Onco-Metabolic Regulation of the Pentose Phosphate Pathway (PPP) and Nucleotide Metabolism in Non-Hodgkin Lymphoma (NHL)

High Glycine Promotes Proliferation and Progression Though Increase of Glutathione Synthesis in Multiple Myeloma

Decitabine Induces Ferroptosis in Myelodysplastic Syndrome

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Linking Stored Red Blood Cell Metabolism to Transfusion Recipient Iron Homeostasis Pathophysiology in Critically-Ill Children

Bach1 Inhibitors Reduce Stasis in Townes Sickle Cell Mouse Model

Glutaminase Inhibition Overcomes Acquired Resistance to Mitochondrial Complex I in NOTCH1-Driven T-Cell Acute Lymphoblastic Leukemias (T-ALL) Via Block of Glutamine Driven Reductive Metabolism

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Glutathione Metabolism Contributes to the Pathobiology of Waldenstrom's Macroglobulinemia

Dual Targeting of ALDH1 and ALDH3: A Promising Therapeutic Approach in Acute Myeloid Leukemia

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Identification of Novel Variants Associated with Fetal Hemoglobin Levels in Healthy Donors (the INTERVAL study)

Untargeted Metabolomics on Dried Blood Spots for the Diagnosis and Clinical Follow up of Rare Hereditary Anemias

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Targeting Autophagy Kinase ULK1 Can Reverse Bcl2 Inhibitor (ABT-199) Induced Autophagy to Overcome Acquired Resistance in Acute Myeloid Leukemia

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Increased Methylation of Deamidated Asparagines and Aspartates in Stored Red Blood Cells from Glucose 6-Phosphate Dehydrogenase-Deficient Blood Donors

Alternative Overexpression of NRF2 or MYC Defines a Subgroup of Poor Prognosis Acute Myeloid Leukemia and Suggests a Novel Therapeutic Strategy By Combined Bromodomain Inhibition and Forced NRF2 Pathway Activation

Hydroxyurea Exhibits Antioxidant Activity Via the Nrf2 Pathway- Antioxidant/Electrophile Response Element Regulated By p62/ SQSTM1

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American Society of Hematology

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ASH Publications

American Society of Hematology

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