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Journal Articles

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Jun Zhu, MD PhD, Grzegorz Nowakowski, MD, Qingyuan Zhang, Joshua Brody, MD, Xiuhua Sun, MD, Joseph Maly, MD, Yuqin Song, MD PhD, Yongping Song, MD PhD, Jennifer Kimberly Lue, MD, Wen Luo, PhD, Lei Zhang, MD, Isabel Han, Manoj Jivani, Young Liu, Ling Li, MD, Joan Sun, MBA, Stephen D. Smith, MD

Blood (2019) 134 (Supplement_1): 5330.

https://doi.org/10.1182/blood-2019-124930

Published: 2019

Journal Articles

MiR-340 Expression As a Prognostic Marker to Guide Clinical Decision-Making in Acute Myeloid Leukemia

Tingting Shao, Yuan Feng, Ninghan Zhang, Rong Wang, Ting Pan, Jianlin Qiao, PhD, Mingshan Niu, PhD, Kailin Xu, MD

Blood (2019) 134 (Supplement_1): 2728.

https://doi.org/10.1182/blood-2019-126522

Published: 2019

Journal Articles

Postnatally Acquired Mutations Underlie the Progression of Transient Leukemia to Myeloid Leukemia of Down Syndrome

Jian Chen, PhD, Yue Li, MD MSC, Fouad Yousif, Sagi Abelson, PhD, Sanaz Manteghi, PhD, John D. McPherson, PhD, Johann K. Hitzler, MD

Blood (2018) 132 (Supplement 1): 442.

https://doi.org/10.1182/blood-2018-99-117198

Published: 2018

Journal Articles

Crispri-Based Screening of Clustered Regulatory Elements Reveals Novel Leukemia Dependencies

Salima Benbarche, PhD, Cécile K Lopez, Thomas Mercher, PhD, Camille Lobry, PhD MSc

Blood (2018) 132 (Supplement 1): 654.

https://doi.org/10.1182/blood-2018-99-111865

Published: 2018

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

Journal Articles

Screening for Immunosuppressive Genes Responsible for Resistance Towards CAR-T Cell Therapy in Cancer Cells

Aygul Valiullina, Alexey Petukhov, Regina Sayarova, Margarita Zhuravleva, MD, Sevindzh Kletukhina, Sergey Malanin, PhD, Emil Bulatov, PhD, Albert Rizvanov, DSc, PhD

Blood (2018) 132 (Supplement 1): 4965.

https://doi.org/10.1182/blood-2018-99-118241

Published: 2018

Journal Articles

Comprehensive Immunophenotyping Panel in Japan Enables to Detect Rare Subtypes in Childhood Leukemia

Takao Deguchi, MD PhD, Nobutaka Kiyokawa, MD PhD, Kentaro Ohki, MD PhD, Yoshiko Hashii, MD, PhD, Atsushi Manabe, Souichi Adachi, MD PhD, Akiko Moriya Saito, MD PhD, Keizo Horibe

Blood (2017) 130 (Supplement 1): 5112.

https://doi.org/10.1182/blood.V130.Suppl_1.5112.5112

Published: 2017

Journal Articles

Extensive RAG-Mediated Rearrangements and Mutations in BCR-ABL1 and BCR - ABL1 -like Adult Acute Lymphoblastic Leukemia

Mathijs A. Sanders, PhD, Anikó Szabó, MD, Carla Exalto, Remco Hoogenboezem, Annelieke Zeilemaker, Jasper E. Koenders, Peter van Geel, Anita Schelen, H. Berna Beverloo, PhD, Jan J. Cornelissen, MD PhD, Anita W. Rijneveld, MD PhD, Peter J.M. Valk, PhD

Blood (2016) 128 (22): 4067.

https://doi.org/10.1182/blood.V128.22.4067.4067

Published: 2016

Journal Articles

A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy

Diana Azzam, PhD, Claude-Henry Volmar, PhD, Al-Ali Hassan, PhD, Aymee Perez, PhD, Justin M. Watts, MD, Fernando Vargas, MD, Roy Elias, Francisco Vega, MD PhD, Arthur Zelent, PhD, Christopher R. Cogle, MD, Claes Wahlestedt, PhD, Ronan T. Swords, MDPhDFRCPI FRCPath

Blood (2015) 126 (23): 1352.

https://doi.org/10.1182/blood.V126.23.1352.1352

Published: 2015

Journal Articles

Methylation of DNMT3B Strongly Associates with the Methylome, Cytogenetic Risk Groups, and Prognosis of Pediatric Acute Myeloid Leukemia

Jatinder K Lamba, PhD, Stanley Pounds, Xueyuan Cao, Susana C. Raimondi, PhD, James R. Downing, MD, Raul C Ribeiro, Jeffrey Rubnitz

Blood (2015) 126 (23): 2434.

https://doi.org/10.1182/blood.V126.23.2434.2434

Published: 2015

Journal Articles

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

Courtney L Jones, PhD, Christy M Gearheart, PhD, Susan Fosmire, Cristina Delgado-Martin, PhD, Faye Pais, MD, Jinhua Wang, PhD, Teena Bhatla, MD, Danielle S Bitterman, Simone R de Rijk, Wallace Bourgeois, Smita C. Dandekar, MD, Elizabeth A. Raetz, MD, Michelle L. Hermiston, MD PhD, Michael J Garabedian, PhD, Christopher C. Porter, MD, William L. Carroll, MD

Blood (2014) 124 (21): 789.

https://doi.org/10.1182/blood.V124.21.789.789

Published: 2014

Journal Articles

UNC-GRK4-1: An Allele Specific Cancer Testis Antigen Identified Through Genomic Screening

Udara Dharamsiri, PhD, Sally A. Hunsucker, PhD, Benjamin G. Vincent, MD, Michael Wu, PhD, Edward J. Collins, PhD, Shoudan Liang, PhD, Jeffrey J. Molldrem, MD, Paul M. Armistead, MD, PhD

Blood (2013) 122 (21): 3246.

https://doi.org/10.1182/blood.V122.21.3246.3246

Published: 2013

Journal Articles

Molecular Characterization Of Myelofibrosis Patients With Cytopenia Treated With Pomalidomide: Results From The Mpnsg 01-09 Study

Frank Stegelmann, MD, Maximilian Laaths, MD, Andreas Reiter, MD, Edgar Jost, Martin Griesshammer, MD, PhD, Norbert Gattermann, MD, Holger Hebart, Cornelius F. Waller, MD, Philippe Schafhausen, MD, Uwe Platzbecker, MD, PhD, Andreas Hochhaus, MD, Walter Verbeek, MD, Igor W. Blau, MD, Carmen Blersch, Susanne Kuhn, Hartmut Döhner, MD, Richard F. Schlenk, MD, Konstanze Döhner, MD

Blood (2013) 122 (21): 4064.

https://doi.org/10.1182/blood.V122.21.4064.4064

Published: 2013

Journal Articles

Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML)

Maximilian Schmutz, Manuela Zucknick, PhD, Richard F. Schlenk, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Christoph Plass, PhD, Lars Bullinger, MD, PhD, Rainer Claus, MD

Blood (2013) 122 (21): 2539.

https://doi.org/10.1182/blood.V122.21.2539.2539

Published: 2013

Journal Articles

Transcriptional Repression Of CDKN2D by PML/RARα Contributes To The Altered Proliferation and Differentiation Block Of Acute Promyelocytic Leukemia Cells

Xiaohong Jia, Yun Tan, Yewei Wang, Xuehua Zhu, Xianwen Yang, Wen Jin, Ji Zhang, Kankan Wang

Blood (2013) 122 (21): 3743.

https://doi.org/10.1182/blood.V122.21.3743.3743

Published: 2013

Journal Articles

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

Akihide Yoshimi, MD, PhD, Takashi Toya, MD, Masahiro Nakagawa, MD, PhD, Masahito Kawazu, MD, PhD, Yasuhito Nannya, MD, PhD, Motoshi Ichikawa, MD, PhD, Shunya Arai, MD, PhD, Hironori Harada, MD, PhD, Kensuke Usuki, MD, PhD, Yasuhide Hayashi, MD, PhD, Etsuro Ito, MD, PhD, Keita Kirito, MD, PhD, Hideaki Nakajima, MD, PhD, Hiroyuki Mano, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 739.

https://doi.org/10.1182/blood.V122.21.739.739

Published: 2013

Journal Articles

Preclinical Assessment of a Novel CDC7 Inhibitor: Genomewide RNAi Screening Identifies Unique Synergetic and Resistance Genes,

Nancy Liu-Sullivan, Bhavneet Bhinder, David Shum, Christina Ramirez, Constantin Radu, Hakim Djaballah, PhD, Mark G. Frattini, MD, PhD

Blood (2011) 118 (21): 3570.

https://doi.org/10.1182/blood.V118.21.3570.3570

Published: 2011

Journal Articles

Genome-Wide Aberrant Splicing in Patients with Acute Myeloid Leukemia (AML) Indetifies Potential Novel Targets

Sophia Adamia, Ph.D, Michal Bar-Natan, M.D, Benjamin Haibe-Kains, Ph.D, Hervé Avet-Loiseau, MD, PhD, Laurence Lode, Ph.D, Samuel Pevzner, Sigitas Verselis, PhD, Edward Fox, PhD, Ilene Galinsky, ANP, John Quackenbush, Ph.D, Richard M. Stone, MD, James D Griffin, MD

Blood (2011) 118 (21): 761.

https://doi.org/10.1182/blood.V118.21.761.761

Published: 2011

Journal Articles

Genome-Wide Association Study for Determinants of Acute Graft Vs Host Disease (aGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation: Development of 7 SNP Model Predicting aGVHD

Eunkyung Park, Song Joo Yang, Inho Kim, Eun Hyung Jeon, Seonyang Park, MD

Blood (2011) 118 (21): 1010.

https://doi.org/10.1182/blood.V118.21.1010.1010

Published: 2011

Journal Articles

Epigenetic Silencing of the Receptor Tyrosine Phosphatase, PTPRK , Located At the Frequently Deleted 6q22.33-q23.2 Region, Leads to Tumor Growth Via the Constitutive Activation of STAT3 in Nasal-Type NK/T-Cell Lymphoma

Yun-Wen Chen, Tianhuan Guo, Lijun Shen, Kai-Yau Wong, Wing-Yan Au, MD, Qian Tao, Lok-Yi Wong, Cheuk-On Tang, Wai Lap Choi, Wei-Ping Liu, Gan-Di Li, Norio Shimizu, Junjiro Tsuchiyama, Florence Loong, Raymond Liang, MD, FRCP, Yok Lam Kwong, MD, Gopesh Srivastava, Ph.D

Blood (2011) 118 (21): 1378.

https://doi.org/10.1182/blood.V118.21.1378.1378

Published: 2011

NARROW

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

MiR-340 Expression As a Prognostic Marker to Guide Clinical Decision-Making in Acute Myeloid Leukemia

Postnatally Acquired Mutations Underlie the Progression of Transient Leukemia to Myeloid Leukemia of Down Syndrome

Crispri-Based Screening of Clustered Regulatory Elements Reveals Novel Leukemia Dependencies

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Screening for Immunosuppressive Genes Responsible for Resistance Towards CAR-T Cell Therapy in Cancer Cells

Comprehensive Immunophenotyping Panel in Japan Enables to Detect Rare Subtypes in Childhood Leukemia

Extensive RAG-Mediated Rearrangements and Mutations in BCR-ABL1 and BCR - ABL1 -like Adult Acute Lymphoblastic Leukemia

A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy

Methylation of DNMT3B Strongly Associates with the Methylome, Cytogenetic Risk Groups, and Prognosis of Pediatric Acute Myeloid Leukemia

MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL

UNC-GRK4-1: An Allele Specific Cancer Testis Antigen Identified Through Genomic Screening

Molecular Characterization Of Myelofibrosis Patients With Cytopenia Treated With Pomalidomide: Results From The Mpnsg 01-09 Study

Differential DNA Methylation Predicts Response To Combined Treatment Regimens With a DNA Methyltransferase Inhibitor In Acute Myeloid Leukemia (AML)

Transcriptional Repression Of CDKN2D by PML/RARα Contributes To The Altered Proliferation and Differentiation Block Of Acute Promyelocytic Leukemia Cells

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

Preclinical Assessment of a Novel CDC7 Inhibitor: Genomewide RNAi Screening Identifies Unique Synergetic and Resistance Genes,

Genome-Wide Aberrant Splicing in Patients with Acute Myeloid Leukemia (AML) Indetifies Potential Novel Targets

Genome-Wide Association Study for Determinants of Acute Graft Vs Host Disease (aGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation: Development of 7 SNP Model Predicting aGVHD

Epigenetic Silencing of the Receptor Tyrosine Phosphatase, PTPRK , Located At the Frequently Deleted 6q22.33-q23.2 Region, Leads to Tumor Growth Via the Constitutive Activation of STAT3 in Nasal-Type NK/T-Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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