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Journal Articles

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

Henrik Østergaard, Jacob Lund, Per J. Greisen, Stine Kjellev, Anette Henriksen, Nikolai Lorenzen, Eva Johansson, Gustav Røder, Morten G. Rasch, Laust B. Johnsen, Thomas Egebjerg, Søren Lund, Henrik Rahbek-Nielsen, Prafull S. Gandhi, Kasper Lamberth, Mette Loftager, Lisbeth M. Andersen, Amalie C. Bonde, Fabian Stavenuiter, Daniel E. Madsen, Xun Li, Thomas L. Holm, Carsten D. Ley, Peter Thygesen, Haisun Zhu, Rong Zhou, Karina Thorn, Zhiru Yang, Mette B. Hermit, Jais R. Bjelke, Bjarne G. Hansen, Ida Hilden
Journal: Blood
Blood (2021) 138 (14): 1258–1268.
https://doi.org/10.1182/blood.2020010331
Published: 2021
Includes: Supplemental data
Journal Articles

Characterization and Disease Management of Persons with Hemophilia A Treated with Emicizumab: A Survey Study of Hematologists in the US

Wendy E. Owens, MA, Anisha M. Patel, PhD, Kathleen Poulos, RN, Janet Bernard, BA, Janet Powers, MPH, MBA, Richard H. Ko, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4941.
https://doi.org/10.1182/blood-2019-123730
Published: 2019
Journal Articles

Aptamers as Rapid Onset and Rapidly Reversible Antithrombotic Agents

Bruce A. Sullenger, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-16.
https://doi.org/10.1182/blood-2019-121056
Published: 2019
Journal Articles

Cofactor and Cofactor Mimetics

Peter J. Lenting, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-17.
https://doi.org/10.1182/blood-2019-121059
Published: 2019
Journal Articles

Real-World Use of Emicizumab in Patients with Hemophilia with and without Inhibitors

Isabella McCary, BS, Christine Guelcher, PPCNP-BC, Jan Kuhn, BA, BSN, MSN, Regina Butler, RN-BC, Gita Massey, Michael F. Guerrera, MD, Lance Ballester, MS, Leslie J. Raffini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1137.
https://doi.org/10.1182/blood-2019-122569
Published: 2019
Journal Articles

Evaluation of a Blood Coagulation Factor IX Variant That Functions Independently of Factor VIII As an Alternative Treatment for Hemophilia A

Viola J.F. Strijbis, MSc, Ka Lei Cheung, Pavlina Konstantinova, PhD, Ying Poi Liu, PhD, Sander J van Deventer, MD PhD, Mettine H.A. Bos, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1110.
https://doi.org/10.1182/blood-2019-124120
Published: 2019
Journal Articles

Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo

Stine L Kjellev, PhDDVM, Henrik Østergaard, PhD, Per Jr Greisen, PhD, Mette B Hermit, PhD, Karina Thorn, PhD, Bjarne G Hansen, PhD, Rong Zhou, PhD, Jais Rose Bjelke, PhD, Marianne Kjalke, PhD, Jacob Lund, PhD, Thomas L Holm, PhD, Carsten Dan Ley, PhD, Daniel Elenius, PhD, Peter Thygesen, PhD, Mette Loftager, PhD, Morten G Rasch, PhD, Nikolai Lorenzen, PhD, Prafull S Gandhi, PhD, Kasper Lamberth, PhD, Thomas Egebjerg, Søren Lund, PhD, Anette Henriksen, PhD, Henrik Rahbek-Nielsen, PhD, Zhiru Yang, Ida Hilden
Journal: Blood
Blood (2019) 134 (Supplement_1): 96.
https://doi.org/10.1182/blood-2019-122817
Published: 2019
Journal Articles

Antithrombin- and Heparin-Binding Exosites Regulate Extravascular Binding and Clearance of Factor IXa

Pamela Westmark, PhD, John P. Sheehan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2392.
https://doi.org/10.1182/blood-2019-131580
Published: 2019
Journal Articles

Peri-Procedural Management and Outcomes of Patients with Hemophilia on Emicizumab Prophylaxis

Isabella McCary, BS, Christine Guelcher, PPCNP-BC, Jan Kuhn, BA, BSN, MSN, Regina Butler, RN-BC, Michael F. Guerrera, MD, Gita Massey, Leslie J. Raffini, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2396.
https://doi.org/10.1182/blood-2019-126944
Published: 2019
Journal Articles

Prospective Controlled Monitoring of Hemlibra Prophylaxis Initiation in a Large Cohort of Hemophilia a Patients- Real World Data

Assaf Arie Barg, Tami Livnat, PhD, Tami Brutman-Barazani, Nurit Rosenberg, Ivan Budnik, MD PhD, Gili Kenet
Journal: Blood
Blood (2019) 134 (Supplement_1): 2397.
https://doi.org/10.1182/blood-2019-122010
Published: 2019
Journal Articles

A Novel Variant of Factor VIII Yields Cofactor Activity without Proteolysis between the A1 and A2 Domains

Manjunath Goolyam Basavaraj, PhD, Sriram Krishnaswamy, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3771.
https://doi.org/10.1182/blood-2018-99-116267
Published: 2018
Journal Articles

A Novel Point-of-Care Whole Blood Coagulation Assay to Monitor Emicizumab Therapy in Patients with Hemophilia

Michael A Suster, PhD, Debnath Maji, M.Tech, Lalitha V. Nayak, MD, Christina Jenkins, MSN-PNP, RN, Susan Hunter, BSN, RN-BC, Alvin H. Schmaier, MD, Pedram Mohseni, PhD, Sanjay Ahuja
Journal: Blood
Blood (2018) 132 (Supplement 1): 2475.
https://doi.org/10.1182/blood-2018-99-113623
Published: 2018
Journal Articles

Biochemical Characteristics of Emicizumab Activity with Factors IXa, X, and VIIa

Dougald Monroe, PhD, Maureane Hoffman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1167.
https://doi.org/10.1182/blood-2018-99-116888
Published: 2018
Journal Articles

Individually Tailored By-Passing Therapy for the Management of Breakthrough Bleeds in Hemophilia Patients with Inhibitors Receiving Prophylaxis with Emicizumab

Yesim Dargaud, MD PhD, Anne Lienhart, MD, Nathalie Enjolras, PhD, Claude Negrier, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3675.
https://doi.org/10.1182/blood.V130.Suppl_1.3675.3675
Published: 2017
Journal Articles

Regulation of Factor VIII By Activated Protein C: Assessment In Vitro and In Vivo

Nicole A. Parsons, B.S., Michelle D. Ho, BS, Robert J. Davidson, BS, Nabil K. Thalji, PhDMD, Ben J. Samelson-Jones, MD PhD, Rodney M Camire, PhD, Lindsey A. George, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3650.
https://doi.org/10.1182/blood.V130.Suppl_1.3650.3650
Published: 2017
Journal Articles

Inhibition of Factor IXa By Protein S: Critical Function of the Protein S SHBG-like Domain

Rima Chattopadhyay, PhD, A'drianne Dorsey, Satish Pilli, PhD, Sumita Choudhury, PhD, Rinku Majumder, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2343.
https://doi.org/10.1182/blood.V130.Suppl_1.2343.2343
Published: 2017
Journal Articles

Activated Factor IX As a Candidate for the Initial Protease in the Coagulation Cascade

Tina M Misenheimer, PhD, Kraig T Kumfer, MD PhD, Barbara E Bates, MS, Brad S Schwartz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 235.
https://doi.org/10.1182/blood.V130.Suppl_1.235.235
Published: 2017
Journal Articles

Targeting Factor Xa Expression in Platelets As a Potential Gene Therapy Strategy for Hemophilia with Inhibitors

Dawei Wang, Xiaohu Shao, Guowei Zhang, PhD, Shuxian Yao, Xielai Zhou, Jianhua Mao, PhD, Zhugang Wang, Zhu Chen, Saijuan Chen
Journal: Blood
Blood (2016) 128 (22): 1171.
https://doi.org/10.1182/blood.V128.22.1171.1171
Published: 2016
Journal Articles

Recombinant Porcine Factor VIII, Obi-1, Successfully Controlled Gastrointestinal Bleeding in a Patient with Acquired Hemophilia A

Muhammad Kashif Riaz, MD, Saulius Girnius, MD, Joseph Edward Palascak, MD FACP
Journal: Blood
Blood (2015) 126 (23): 4676.
https://doi.org/10.1182/blood.V126.23.4676.4676
Published: 2015
Journal Articles

Recombinant Thrombomodulin for the Treatment of Transplantation-Associated Coagulopathy after Allogeneic Hematopoietic Stem Cell Transplantation: A Multi-Center Study in Japan

Kazuyoshi Ishii, MD MPH, PhD, Shosaku Nomura, MD PhD, Shinya Fujita, MD PhD, Atushi Satake, MD PhD, Tomoki Ito, MDPhD, Yuta Katayama, MD PhD, Taiichi Kyo, MD PhD, Shuichi Ota, MD PhD, Masanori Seki, MD PhD, Shigeru Chiba, MD PhD, Yoshinobu Maeda, MD PhD, Mitsune Tanimoto, MD PhD, Takayuki Ikezoe, MD PhD, Hideo Yagi, MD PhD, Kunio Hayashi, MD PhD, Yoji Ishida, MD, PhD, Naohito Fujishima, MD PhD, Kenichi Sawada, MD, PhD, Masaya Okada, MD PhD, Hiroyasu Ogawa, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4341.
https://doi.org/10.1182/blood.V126.23.4341.4341
Published: 2015