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Mette B. Hermit
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Journal Articles

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

Henrik Østergaard, Jacob Lund, Per J. Greisen, Stine Kjellev, Anette Henriksen, Nikolai Lorenzen, Eva Johansson, Gustav Røder, Morten G. Rasch, Laust B. Johnsen, Thomas Egebjerg, Søren Lund, Henrik Rahbek-Nielsen, Prafull S. Gandhi, Kasper Lamberth, Mette Loftager, Lisbeth M. Andersen, Amalie C. Bonde, Fabian Stavenuiter, Daniel E. Madsen, Xun Li, Thomas L. Holm, Carsten D. Ley, Peter Thygesen, Haisun Zhu, Rong Zhou, Karina Thorn, Zhiru Yang, Mette B. Hermit, Jais R. Bjelke, Bjarne G. Hansen, Ida Hilden
Journal: Blood
Blood (2021) 138 (14): 1258–1268.
https://doi.org/10.1182/blood.2020010331
Published: 2021
Includes: Supplemental data
Journal Articles

Next-Generation FVIII Mimetic Shows Superior Effect in a FIX- and Fx-Humanized Mouse Model In Vivo

Carsten Dan Ley, PhD, Thomas Lindebo Holm, PhD, Daniel Elenius, PhD, Heidi Lindgreen Holmberg, PhD, Jais Rose Bjelke, PhD, Mette Loftager, PhD, Mette B Hermit, PhD, Ida Hilden, Stine L Kjellev, PhDDVM
Journal: Blood
Blood (2019) 134 (Supplement_1): 3631.
https://doi.org/10.1182/blood-2019-128159
Published: 2019
Journal Articles

Evaluation of a Next-Generation FVIII Mimetic Antibody, Mim8, in Combination with Recombinant FVIIa, FVIII and Activated Prothrombin Complex Concentrate

Laurent Burnier, PhD, Mette B Hermit, PhD, Ida Hilden, Mirella Ezban, PhD, Stine L Kjellev, PhDDVM
Journal: Blood
Blood (2019) 134 (Supplement_1): 2388.
https://doi.org/10.1182/blood-2019-123340
Published: 2019
Journal Articles

Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo

Stine L Kjellev, PhDDVM, Henrik Østergaard, PhD, Per Jr Greisen, PhD, Mette B Hermit, PhD, Karina Thorn, PhD, Bjarne G Hansen, PhD, Rong Zhou, PhD, Jais Rose Bjelke, PhD, Marianne Kjalke, PhD, Jacob Lund, PhD, Thomas L Holm, PhD, Carsten Dan Ley, PhD, Daniel Elenius, PhD, Peter Thygesen, PhD, Mette Loftager, PhD, Morten G Rasch, PhD, Nikolai Lorenzen, PhD, Prafull S Gandhi, PhD, Kasper Lamberth, PhD, Thomas Egebjerg, Søren Lund, PhD, Anette Henriksen, PhD, Henrik Rahbek-Nielsen, PhD, Zhiru Yang, Ida Hilden
Journal: Blood
Blood (2019) 134 (Supplement_1): 96.
https://doi.org/10.1182/blood-2019-122817
Published: 2019
Journal Articles

Modulating the Antithrombin-Mediated in Vivo Clearance of Coagulation Factor VIIa

Henrik Østergaard, PhD, Lene Hansen, Hermann Pelzer, PhD, Henrik Agersø, Anette A. Pedersen, Tina H. Glue, Laust B. Johnsen, PhD, Gorm Andersen, Jais R. Bjelke, Jens Breinholt, Henning Stennicke, MSc, PhD, Prafull S. Gandhi, PhD, Ole H. Olsen, PhD, Mette B. Hermit
Journal: Blood
Blood (2014) 124 (21): 4233.
https://doi.org/10.1182/blood.V124.21.4233.4233
Published: 2014
Journal Articles

Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide

Henrik Østergaard, Jais R. Bjelke, Lene Hansen, Lars Christian Petersen, Anette A. Pedersen, Torben Elm, Flemming Møller, Mette B. Hermit, Pernille K. Holm, Thomas N. Krogh, Jørn M. Petersen, Mirella Ezban, Brit B. Sørensen, Mette D. Andersen, Henrik Agersø, Haleh Ahmadian, Kristoffer W. Balling, Marie Louise S. Christiansen, Karin Knobe, Timothy C. Nichols, Søren E. Bjørn, Mikael Tranholm
Journal: Blood
Blood (2011) 118 (8): 2333–2341.
https://doi.org/10.1182/blood-2011-02-336172
Published: 2011
Includes: Supplemental data