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Prafull S. Gandhi
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Journal Articles

A Phase 1/2, First-in-Human, Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Participants with Glanzmann Thrombasthenia

Suthesh Sivapalaratnam, Steve Austin, Ulrike Lorch, Thomas York, Andrew Want, Ashley Gosnell, Prafull S. Gandhi, Henrik Østergaard, Erik Bjornson, Tara O'Meara, Benny Sorensen, Roger E.G. Schutgens, Catherine Rea
Journal: Blood
Blood (2023) 142 (Supplement 1): 1225.
https://doi.org/10.1182/blood-2023-187279
Published: 2023
Journal Articles

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

Henrik Østergaard, Jacob Lund, Per J. Greisen, Stine Kjellev, Anette Henriksen, Nikolai Lorenzen, Eva Johansson, Gustav Røder, Morten G. Rasch, Laust B. Johnsen, Thomas Egebjerg, Søren Lund, Henrik Rahbek-Nielsen, Prafull S. Gandhi, Kasper Lamberth, Mette Loftager, Lisbeth M. Andersen, Amalie C. Bonde, Fabian Stavenuiter, Daniel E. Madsen, Xun Li, Thomas L. Holm, Carsten D. Ley, Peter Thygesen, Haisun Zhu, Rong Zhou, Karina Thorn, Zhiru Yang, Mette B. Hermit, Jais R. Bjelke, Bjarne G. Hansen, Ida Hilden
Journal: Blood
Blood (2021) 138 (14): 1258–1268.
https://doi.org/10.1182/blood.2020010331
Published: 2021
Includes: Supplemental data
Journal Articles

Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo

Stine L Kjellev, PhDDVM, Henrik Østergaard, PhD, Per Jr Greisen, PhD, Mette B Hermit, PhD, Karina Thorn, PhD, Bjarne G Hansen, PhD, Rong Zhou, PhD, Jais Rose Bjelke, PhD, Marianne Kjalke, PhD, Jacob Lund, PhD, Thomas L Holm, PhD, Carsten Dan Ley, PhD, Daniel Elenius, PhD, Peter Thygesen, PhD, Mette Loftager, PhD, Morten G Rasch, PhD, Nikolai Lorenzen, PhD, Prafull S Gandhi, PhD, Kasper Lamberth, PhD, Thomas Egebjerg, Søren Lund, PhD, Anette Henriksen, PhD, Henrik Rahbek-Nielsen, PhD, Zhiru Yang, Ida Hilden
Journal: Blood
Blood (2019) 134 (Supplement_1): 96.
https://doi.org/10.1182/blood-2019-122817
Published: 2019
Journal Articles

Protein Engineering and in Vitro Characterization of a Factor VIIa Analog with Selective Abrogation of Tissue Factor Binding

Prafull S. Gandhi, PhD, Hanne Grøn, PhD, Helle H Petersen, PhD, Stine L Reedtz-Runge, DVM, PhD, Ole H. Olsen, PhD, Henrik Østergaard, PhD
Journal: Blood
Blood (2014) 124 (21): 4230.
https://doi.org/10.1182/blood.V124.21.4230.4230
Published: 2014
Journal Articles

Modulating the Antithrombin-Mediated in Vivo Clearance of Coagulation Factor VIIa

Henrik Østergaard, PhD, Lene Hansen, Hermann Pelzer, PhD, Henrik Agersø, Anette A. Pedersen, Tina H. Glue, Laust B. Johnsen, PhD, Gorm Andersen, Jais R. Bjelke, Jens Breinholt, Henning Stennicke, MSc, PhD, Prafull S. Gandhi, PhD, Ole H. Olsen, PhD, Mette B. Hermit
Journal: Blood
Blood (2014) 124 (21): 4233.
https://doi.org/10.1182/blood.V124.21.4233.4233
Published: 2014