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Journal Articles

IPO11 Is Upregulated in Relapsed AML and Supports Survival of Leukemic Stem Cells

Boaz Nachmias, MD PhD, Veronique Voisin, PhD, Rose Hurren, BSc, Xioaming Wang, Neil Maclean, G. Wei Xu, Ayesh K Seneviratne, BSc, MSc, Changjiang Xu, Gary D Bader, Liran I. Shlush, MD, Aaron D Schimmer, MD PhD

Blood (2019) 134 (Supplement_1): 2530.

https://doi.org/10.1182/blood-2019-122284

Published: 2019

Journal Articles

Decitabine-Induced Early Platelet Response, a Predictor of Favorable Outcome during Hypomethylating Treatment of MDS, Is Associated with In Vivo Megakaryocytic Differentiation

Julia Stomper, Annette M. May, Tina E. Joeckel, Peter Bronsert, Martin Werner, Michael Lübbert

Blood (2019) 134 (Supplement_1): 4265.

https://doi.org/10.1182/blood-2019-128141

Published: 2019

Journal Articles

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Steven de Maat, Wariya Sanrattana, Reiner K. Mailer, Naomi M. J. Parr, Martin Hessing, Robert M. Koetsier, Joost C. M. Meijers, Gerard Pasterkamp, Thomas Renné, Coen Maas

Blood (2019) 134 (19): 1658–1669.

https://doi.org/10.1182/blood.2019000481

Published: 2019

Includes: Supplemental data

Journal Articles

Statins Potentiate Aminopeptidase Inhibitor (pro)Drug Activity in Acute Myeloid Leukemia Cells

Jacqueline Cloos, PhD, Godefridus J Peters, PhD, Marjon Al, BSc, Yehuda G Assaraf, PhD, Lixia Wang, PhD, Jack W. Singer, MD, Jorge E. Cortes, MD, Gert J. Ossenkoppele, MD PhD, Gerrit Jansen, PhD

Blood (2018) 132 (Supplement 1): 3945.

https://doi.org/10.1182/blood-2018-99-114447

Published: 2018

Journal Articles

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Blood (2018) 132 (Supplement 1): 1339.

https://doi.org/10.1182/blood-2018-99-111015

Published: 2018

Journal Articles

Diagnostic Utility of Flow Cytometric Immunophenotyping in Chronic Myelomonocytic Leukemia

Leonor Arenillas, MD PhD, Ivonne Parraga, Fellow, Lourdes Florensa, MD PhD, Sara Montesdeoca Romero, MD, Anna Puiggros, PhD, Marta Salido, PhD, Blanca Espinet, PhD, Anna Angona, MD PhD, Ana Ferrer, MD PhD, Carme Pedro, MD, Xavier Calvo, MD

Blood (2018) 132 (Supplement 1): 5526.

https://doi.org/10.1182/blood-2018-99-119689

Published: 2018

Journal Articles

Poor Responsiveness to Low-Dose Aspirin Contributes to Persistent In Vivo Platelet Activation in Polycythemia Vera

Paola Ranalli, MD, Giovanna Petrucci, PhD, Alfredo Dragani, MD, Mauro Di Ianni, MD PhD, Paolo Di Bartolomeo, MD, Viviana Cavalca, BSc, Benedetta Porro, PhD, Elena Tremoli, PhD, Carlo Patrono, MD, Bianca Rocca, MD

Blood (2017) 130 (Supplement 1): 2379.

https://doi.org/10.1182/blood.V130.Suppl_1.2379.2379

Published: 2017

Journal Articles

The Thymidine Dideoxynucleoside Analogue, Alovudine, Inhibits the Mitochondrial DNA Polyermase, POLG, Impairs Oxidative Phosphorylation and Promotes Monocytic Differentiation in AML

Dana Yehudai-Ofir, MD, Sanduni U. Liyanage, Hon. B. Sc, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Danny V. Jeyaraju, PhD, Xiaoming Wang, Thirushi Siriwardena, Yulia Jitkova, PhD, Aaron D. Schimmer, MDPhD, Biljana Rizoska, PhD, Paul Targett-Adams, PhD, Mark Albertella, PhD

Blood (2017) 130 (Supplement 1): 2524.

https://doi.org/10.1182/blood.V130.Suppl_1.2524.2524

Published: 2017

Journal Articles

Tafazzin (TAZ) Regulates the Differentiation of AML Cells By Reducing Levels of the Phospholipid Phosphatidylethanolamine

Blood (2017) 130 (Supplement 1): 788.

https://doi.org/10.1182/blood.V130.Suppl_1.788.788

Published: 2017

Journal Articles

Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Controlling Pyruvate Entry into the Mitochondria, Nuclear Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Dilshad H. Khan, Michael Mullokandov, Yan Wu, Marcela Gronda, MSc, Rose Hurren, BSc, Xiaoming Wang, Neil MacLean, Danny V. Jeyaraju, PhD, G. Wei Xu, Rob C. Laister, PhD, Zachary Blatman, Troy Ketela, Mark D. Minden, MD PhD, Atan Gross, PhD, Aaron D. Schimmer, MDPhD

Blood (2017) 130 (Supplement 1): 299.

https://doi.org/10.1182/blood.V130.Suppl_1.299.299

Published: 2017

Journal Articles

Revisiting Cytochemical Myeloperoxidase (MPO) Stain for Early Diagnosis of Acute Promyelocytic Leukemia (APML) in Areas with Limited Resources: An Experience from a Tertiary Care Center in India

Annapurna Saksena, MD MBBS, Parth Desai, MD MBBS, Vishal Chauhan, MD, Naresh Gupta, MD, Tejinder Singh

Blood (2017) 130 (Supplement 1): 5096.

https://doi.org/10.1182/blood.V130.Suppl_1.5096.5096

Published: 2017

Journal Articles

Inhibiting the Mitochondrial Sulfhydryl Oxidase Alr Reduces Cox17 and Alters Mitochondrial Cristae Structure Leading to the Differentiation of AML and Stem Cells

Danny V. Jeyaraju, PhD, Veronique Voisin, Changjiang Xu, Samir H. Barghout, BSPharm, MSc, Dilshad H. Khan, Rose Hurren, BSc, Marcela Gronda, MSc, Xiaoming Wang, Yulia Jitkova, PhD, David Sharon, PhD, Sanduni U. Liyanage, Hon. B. Sc, PhD, Joelle Soriano, Eric R. Lechman, PhD, Neil MacLean, Mark D. Minden, MD PhD, Steven M. Chan, MDPhD, John E. Dick, PhD, Gary D Bader, Aaron D. Schimmer, MDPhD

Blood (2017) 130 (Supplement 1): 881.

https://doi.org/10.1182/blood.V130.Suppl_1.881.881

Published: 2017

Journal Articles

The Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Influencing the Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Dilshad H. Khan, PhD, Michael Mullokandov, Yan Wu, Marcela Gronda, Rose Hurren, Xiaoming Wang, Neil MacLean, Rob C. Laister, PhD, Atan Gross, Aaron D. Schimmer, MD PhD

Blood (2016) 128 (22): 1562.

https://doi.org/10.1182/blood.V128.22.1562.1562

Published: 2016

Journal Articles

Biological Description of 109 Cases of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) from the French Network of BPDCN

Eve Poret, Fanny Angelot Delettre, Sabeha Biichle, Anne Roogy, Louis Benazet, Maider Pagadoy, Chrystelle Vidal, Franck Leroux, Véronique Harrivel, Christophe Ferrand, PhD, Veronique Salaun, Zehaira Benseddik, Julien Guy, Marie Christine Jacob, Christophe Roumier, Jean Feuillard, Liliana Vila, Lucile Baseggio, Adriana Plesa, Christine Arnoulet, B Benet, Bernard Drenou, MD, Veronique Latger Cannard, Marie-Christine Bene, MD, Michel Ticchioni, Daniel Lusina, Valerie Bardet, Magalie LE Garff Tavernier, Elizabeth Macintyre, MD PhD, Vahid Asnafi, MDPhD, Maria Elena Noguera, Sabrina Bouyer, Carine Lecoq Lafon, Mikael Roussel, MD PhD, Fabrice Jardin, Francoise Solly, MD, Lydia Campos, MD PhD, Anne Galoisy, Anne Arnaud, Sylvie Daliphard, Franck Genevieve, MD PhD, Romaric Lacroix, Françoise Schillinger, Estelle Seilles, Delphine Binda, Eric Deconinck, Philippe Saas, PhD, Francine Garnache Ottou, PhD

Blood (2015) 126 (23): 3812.

https://doi.org/10.1182/blood.V126.23.3812.3812

Published: 2015

Journal Articles

Genes Associated with Alloimmunization to Blood Group Antigens in Sickle Cell Disease

Jacqueline N. Milton, PhD, Allison E. Ashley-Koch, PhD, Melanie E. Garrett, MS, Karen L. Soldano, B.S., Eugene P. Orringer, MD, Paola Sebastiani, PhD, Daniel A. Dworkis, MD PhD, Karen Quillen, MD MPH, Martin H. Steinberg, MD, Marilyn J. Telen, MD

Blood (2014) 124 (21): 762.

https://doi.org/10.1182/blood.V124.21.762.762

Published: 2014

Journal Articles

The Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) Shows Selective In Vitro Efficacy In Monocytoid-Lineage Acute Myeloid Leukaemia (AML)

Joanna Zabkiewicz, PhD, Marie Gilmour, Robert K. Hills, Elizabeth Bone, Alan Davidson, Alan K. Burnett, MD, Steven Knapper, MD

Blood (2013) 122 (21): 1297.

https://doi.org/10.1182/blood.V122.21.1297.1297

Published: 2013

Journal Articles

A Specific Mechanism By Which NPM1 mutations Impede Myeloid Differentiation Also Explains The Link With DNMT3A Mutation

Xiaorong Gu, PhD, Reda Z Mahfouz, MD/PhD, Francis Enane, MS, Zhenbo Hu, MD, PhD, Michael J. Clemente, Bartlomiej P Przychodzen, PhD, Mikkael A. Sekeres, MD, MS, Anjali S. Advani, MD, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, MD, PhD, Yogen Saunthararajah, M.D.

Blood (2013) 122 (21): 1254.

https://doi.org/10.1182/blood.V122.21.1254.1254

Published: 2013

Journal Articles

Extra-Nuclear Dislocation of PU.1 but Not CEBPA by Mutated NPM1 in AML Explains Lineage-Associations, ATRA Therapeutic Potential and DNMT3A Secondary Mutation.

Xiaorong Gu, PhD, Reda Z Mahfouz, MD/PhD, Zhenbo Hu, MD, PhD, Yogenthiran Saunthararajah, MD

Blood (2012) 120 (21): 2427.

https://doi.org/10.1182/blood.V120.21.2427.2427

Published: 2012

Journal Articles

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Jhas Bozhena, BSc, Shrivani Sriskanthadevan, PhD, Marko Skrtic, PhD, Mahadeo A. Sukhai, PhD, Veronique Voisin, PhD, Yulia Jitkova, PhD, Marcela Gronda, MSc, Rose Hurren, BSc, Xiaoming Wang, Rob C. Laister, PhD, Gary D. Bader, Ph.D., Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD

Blood (2012) 120 (21): 1364.

https://doi.org/10.1182/blood.V120.21.1364.1364

Published: 2012

Journal Articles

Assessment of Cross-Reactivity in Three Different Fecal Occult Blood Test Systems with Dabigatran and Dabigatran Etexilate: Identification of Useful Test Methods

Ashley M Goss, PhD, Joanne van Ryn, PhD, Johanna Schurer, Andreas Clemens, MD

Blood (2012) 120 (21): 4360.

https://doi.org/10.1182/blood.V120.21.4360.4360

Published: 2012

NARROW

IPO11 Is Upregulated in Relapsed AML and Supports Survival of Leukemic Stem Cells

Decitabine-Induced Early Platelet Response, a Predictor of Favorable Outcome during Hypomethylating Treatment of MDS, Is Associated with In Vivo Megakaryocytic Differentiation

Design and characterization of α1-antitrypsin variants for treatment of contact system–driven thromboinflammation

Statins Potentiate Aminopeptidase Inhibitor (pro)Drug Activity in Acute Myeloid Leukemia Cells

Targeting the Mitochondrial Metallochaperone Cox17 Reduces DNA Methylation and Promotes AML Differentiation through a Copper Dependent Mechanism

Diagnostic Utility of Flow Cytometric Immunophenotyping in Chronic Myelomonocytic Leukemia

Poor Responsiveness to Low-Dose Aspirin Contributes to Persistent In Vivo Platelet Activation in Polycythemia Vera

The Thymidine Dideoxynucleoside Analogue, Alovudine, Inhibits the Mitochondrial DNA Polyermase, POLG, Impairs Oxidative Phosphorylation and Promotes Monocytic Differentiation in AML

Tafazzin (TAZ) Regulates the Differentiation of AML Cells By Reducing Levels of the Phospholipid Phosphatidylethanolamine

Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Controlling Pyruvate Entry into the Mitochondria, Nuclear Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Revisiting Cytochemical Myeloperoxidase (MPO) Stain for Early Diagnosis of Acute Promyelocytic Leukemia (APML) in Areas with Limited Resources: An Experience from a Tertiary Care Center in India

Inhibiting the Mitochondrial Sulfhydryl Oxidase Alr Reduces Cox17 and Alters Mitochondrial Cristae Structure Leading to the Differentiation of AML and Stem Cells

The Mitochondrial Carrier Homolog 2 (MTCH2) Regulates the Differentiation of AML Cells By Influencing the Localization of Pyruvate Dehydrogenase Complex and H3 and H4 Histone Acetylation

Biological Description of 109 Cases of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) from the French Network of BPDCN

Genes Associated with Alloimmunization to Blood Group Antigens in Sickle Cell Disease

The Targeted Histone Deacetylase Inhibitor Tefinostat (CHR-2845) Shows Selective In Vitro Efficacy In Monocytoid-Lineage Acute Myeloid Leukaemia (AML)

A Specific Mechanism By Which NPM1 mutations Impede Myeloid Differentiation Also Explains The Link With DNMT3A Mutation

Extra-Nuclear Dislocation of PU.1 but Not CEBPA by Mutated NPM1 in AML Explains Lineage-Associations, ATRA Therapeutic Potential and DNMT3A Secondary Mutation.

Chronic Inhibition of Mitochondrial Translation Alters Metabolism and Stemness in AML

Assessment of Cross-Reactivity in Three Different Fecal Occult Blood Test Systems with Dabigatran and Dabigatran Etexilate: Identification of Useful Test Methods

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American Society of Hematology

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American Society of Hematology

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